SHIP2 and its involvement in various diseases

The Akt kinases: Isoform specificity in metabolism and cancer

(2011) Eva Gonzalez et al.   CELL CYCLE

Enteropathogenic Escherichia coli Recruits the Cellular Inositol Phosphatase SHIP2 to Regulate Actin-Pedestal Formation

(2010) Katherine Smith et al.   Cell Host & Microbe

APOE-4 Genotype and Neurophysiological Vulnerability to Alzheimer's and Cognitive Aging

(2009) Susan Bookheimer et al.   Annual Review of Clinical Psychology

MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1

(2009) Heesang Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

(2009) Lisa M. Ooms et al.   BIOCHEMICAL JOURNAL

Specific Tyrosine Phosphorylations Mediate Signal-Dependent Stimulation of SHIP2 Inositol Phosphatase Activity, while the SH2 Domain Confers an Inhibitory Effect To Maintain the Basal Activity

(2009) Nagendra K. Prasad et al.   BIOCHEMISTRY

The SH2 Domains of Inositol Polyphosphate 5-Phosphatases SHIP1 and SHIP2 Have Similar Ligand Specificity but Different Binding Kinetics

(2009) Yanyan Zhang et al.   BIOCHEMISTRY

Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2

(2009) A Suwa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cell biology of the movement of breast cancer cells: Intracellular signalling and the actin cytoskeleton

(2009) Ping Jiang et al.   CANCER LETTERS

miR-205 Exerts Tumor-Suppressive Functions in Human Prostate through Down-regulation of Protein Kinase C 

(2009) P. Gandellini et al.   CANCER RESEARCH

Suppression of cell growth and invasion by miR-205 in breast cancer

(2009) Hailong Wu et al.   CELL RESEARCH

Inhibitors of the Lipid Phosphatase SHIP2 Discovered by High Throughput Affinity Selection-Mass Spectrometry Screening of Combinatorial Libraries

(2009) D. Annis et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase☆

(2009) Amit Gupta et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

NMR Studies of a Heterotypic Sam−Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor†,‡

(2008) Marilisa Leone et al.   BIOCHEMISTRY

Evolution of cell interactions with extracellular matrix during carcinogenesis

(2008) A. Y. Alexandrova   BIOCHEMISTRY-MOSCOW

The docking properties of SHIP2 influence both JIP1 tyrosine phosphorylation and JNK activity

(2008) Jingwei Xie et al.   CELLULAR SIGNALLING

Akt as a therapeutic target in cancer

(2008) Linda S Steelman et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia

(2008) J. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Expression of Obesity-Linked Phosphatase SHIP2 in Invasive Breast Cancer Correlates with Reduced Disease-Free Survival

(2008) Nagendra K. Prasad et al.   TUMOR BIOLOGY

Impact of Transgenic Overexpression of SH2-Containing Inositol 5′-Phosphatase 2 on Glucose Metabolism and Insulin Signaling in Mice

(2007) Syota Kagawa et al.   ENDOCRINOLOGY