Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity

Genes and molecular pathways underpinning ciliopathies

(2017) Jeremy F. Reiter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cilia and Obesity

(2017) Christian Vaisse et al.   Cold Spring Harbor Perspectives in Biology

Melanocortin-4 receptor–regulated energy homeostasis

(2016) Michael J Krashes et al.   NATURE NEUROSCIENCE

A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH

(2016) Henning Fenselau et al.   NATURE NEUROSCIENCE

Adenylate cyclase 3: a new target for anti-obesity drug development

(2016) L. Wu et al.   Obesity Reviews

A neural basis for melanocortin-4 receptor–regulated appetite

(2015) Alastair S Garfield et al.   NATURE NEUROSCIENCE

A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice

(2014) Peter Acs et al.   Brain Structure & Function

Neurobiology of food intake in health and disease

(2014) Gregory J. Morton et al.   NATURE REVIEWS NEUROSCIENCE

Genome-wide association study of height-adjusted BMI in childhood identifies functional variant inADCY3

(2014) Evangelia Stergiakouli et al.   Obesity

Morbid Obesity Resulting from Inactivation of the Ciliary Protein CEP19 in Humans and Mice

(2013) Adel Shalata et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GPR88 Reveals a Discrete Function of Primary Cilia as Selective Insulators of GPCR Cross-Talk

(2013) Aaron Marley et al.   PLoS One

Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR

(2012) Baran A Ersoy et al.   Nature Chemical Biology

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuronal ciliary signaling in homeostasis and disease

(2010) Jill A. Green et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

The Extracellular Domain of Smoothened Regulates Ciliary Localization and Is Required for High-Level Hh Signaling

(2009) Pia Aanstad et al.   CURRENT BIOLOGY

In silico mutagenesis: a case study of the melanocortin 4 receptor

(2009) Yana Bromberg et al.   FASEB JOURNAL

Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study

(2008) M. A. Calton et al.   HUMAN MOLECULAR GENETICS

Identification of Ciliary Localization Sequences within the Third Intracellular Loop of G Protein-coupled Receptors

(2008) Nicolas F. Berbari et al.   MOLECULAR BIOLOGY OF THE CELL