Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos
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Title
Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos
Authors
Keywords
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Journal
NATURE CELL BIOLOGY
Volume 20, Issue 2, Pages 144-151
Publisher
Springer Nature
Online
2018-01-15
DOI
10.1038/s41556-017-0017-8
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Note: Only part of the references are listed.- Principles of early human development and germ cell program from conserved model systems
- (2017) Toshihiro Kobayashi et al. NATURE
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- (2014) William C. Copeland et al. DNA REPAIR
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- Universal heteroplasmy of human mitochondrial DNA
- (2012) B. A. I. Payne et al. HUMAN MOLECULAR GENETICS
- Mitochondrial disorders as windows into an ancient organelle
- (2012) Scott B. Vafai et al. NATURE
- Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission
- (2012) Christoph Freyer et al. NATURE GENETICS
- Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and Humans
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- Bioenergetics, the origins of complexity, and the ascent of man
- (2010) D. C. Wallace PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- VarScan: variant detection in massively parallel sequencing of individual and pooled samples
- (2009) Daniel C. Koboldt et al. BIOINFORMATICS
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
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- (2008) Lynsey M Cree et al. NATURE GENETICS
- Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease
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- A comprehensive, non-invasive visualization of primordial germ cell development in mice by the Prdm1-mVenus and Dppa3-ECFP double transgenic reporter
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- Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA
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