Principles of early human development and germ cell program from conserved model systems

Stem Cells: A Renaissance in Human Biology Research

(2016) Jun Wu et al.   CELL

Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types

(2016) Kyle M. Loh et al.   CELL

The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion

(2016) Kotaro Sasaki et al.   DEVELOPMENTAL CELL

NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers

(2016) Kazuhiro Murakami et al.   NATURE

A developmental coordinate of pluripotency among mice, monkeys and humans

(2016) Tomonori Nakamura et al.   NATURE

Specification and epigenetic programming of the human germ line

(2016) Walfred W. C. Tang et al.   NATURE REVIEWS GENETICS

Placentation in mammals: Definitive placenta, yolk sac, and paraplacenta

(2016) A.M. Carter et al.   THERIOGENOLOGY

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells

(2015) Fan Guo et al.   CELL

DNA Demethylation Dynamics in the Human Prenatal Germline

(2015) Sofia Gkountela et al.   CELL

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

(2015) Walfred W.C. Tang et al.   CELL

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

(2015) Naoko Irie et al.   CELL

Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells

(2015) Kotaro Sasaki et al.   Cell Stem Cell

The pluripotent state in mouse and human

(2015) K. C. Davidson et al.   DEVELOPMENT

Conserved and divergent expression patterns of markers of axial development in eutherian mammals

(2015) Michio Yoshida et al.   DEVELOPMENTAL DYNAMICS

Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile

(2015) F. Sugawa et al.   EMBO JOURNAL

Improvement of Cell Survival During Human Pluripotent Stem Cell Definitive Endoderm Differentiation

(2015) Han Wang et al.   STEM CELLS AND DEVELOPMENT

Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

(2014) Kyle M. Loh et al.   Cell Stem Cell

Mouse and human blastocyst-derived stem cells: vive les differences

(2014) J. Rossant   DEVELOPMENT

Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation

(2014) Griselda Valdez Magaña et al.   DEVELOPMENTAL BIOLOGY

SOX17 links gut endoderm morphogenesis and germ layer segregation

(2014) Manuel Viotti et al.   NATURE CELL BIOLOGY

Suppression of the SOX2 Neural Effector Gene by PRDM1 Promotes Human Germ Cell Fate in Embryonic Stem Cells

(2014) I-Ying Lin et al.   Stem Cell Reports

A Mesodermal Factor, T, Specifies Mouse Germ Cell Fate by Directly Activating Germline Determinants

(2013) Shinya Aramaki et al.   DEVELOPMENTAL CELL

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

(2013) Nils Grabole et al.   EMBO REPORTS

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

A tripartite transcription factor network regulates primordial germ cell specification in mice

(2013) Erna Magnúsdóttir et al.   NATURE CELL BIOLOGY

Epithelial-mesenchymal transitions: insights from development

(2012) J. Lim et al.   DEVELOPMENT

The role of transcription factor Tcfap2c/TFAP2C in trophectoderm development

(2012) Peter Kuckenberg et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

(2011) Katsuhiko Hayashi et al.   CELL

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

The Sda/GM2-glycan is a carbohydrate marker of porcine primordial germ cells and of a subpopulation of spermatogonia in cattle, pigs, horses and llama

(2011) K Klisch et al.   REPRODUCTION

Pig Epiblast Stem Cells Depend on Activin/Nodal Signaling for Pluripotency and Self-Renewal

(2010) Ramiro Alberio et al.   STEM CELLS AND DEVELOPMENT

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

(2008) Masashi Yamaji et al.   NATURE GENETICS

A protocol describing the use of a recombinant protein-based, animal product-free medium (APEL) for human embryonic stem cell differentiation as spin embryoid bodies

(2008) Elizabeth S Ng et al.   Nature Protocols