Expanding the roles for 2-oxoglutarate-dependent oxygenases in plant metabolism

The 2-oxoglutarate-dependent dioxygenase superfamily participates in tanshinone production in Salvia miltiorrhiza

(2017) Zhichao Xu et al.   JOURNAL OF EXPERIMENTAL BOTANY

Tying the knot: occurrence and possible significance of gene fusions in plant metabolism and beyond

(2017) Jillian M Hagel et al.   JOURNAL OF EXPERIMENTAL BOTANY

A bacterial artificial chromosome (BAC) genomic approach reveals partial clustering of the furanocoumarin pathway genes in parsnip

(2017) Sandro Roselli et al.   PLANT JOURNAL

A 2-Oxoglutarate-Dependent Dioxygenase Mediates the Biosynthesis of Glucoraphasatin in Radish

(2017) Tomohiro Kakizaki et al.   PLANT PHYSIOLOGY

A Dioxygenase Catalyzes Steroid 16α-Hydroxylation in Steroidal Glycoalkaloid Biosynthesis

(2017) Masaru Nakayasu et al.   PLANT PHYSIOLOGY

Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate

(2017) Zhihong Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase

(2017) Xiangzhong Sun et al.   Nature Communications

Transcriptional Responses to the Auxin Hormone

(2016) Dolf Weijers et al.   Annual Review of Plant Biology

Ferrous iron and α-ketoglutarate-dependent dioxygenases in the biosynthesis of microbial natural products

(2016) Long-Fei Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Oxidative Cyclization in Natural Product Biosynthesis

(2016) Man-Cheng Tang et al.   CHEMICAL REVIEWS

Catalytic strategies of the non-heme iron dependent oxygenases and their roles in plant biology

(2016) Mark D White et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Tropane and Granatane Alkaloid Biosynthesis: A Systematic Analysis

(2016) Neill Kim et al.   MOLECULES

Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway

(2016) Vilja Siitonen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dioxygenase-encodingAtDAO1gene controls IAA oxidation and homeostasis inArabidopsis

(2016) Silvana Porco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic regulation of auxin oxidase and conjugating enzymesAtDAO1andGH3modulates auxin homeostasis

(2016) Nathan Mellor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DAO1 catalyzes temporal and tissue-specific oxidative inactivation of auxin inArabidopsis thaliana

(2016) Jun Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LATERAL BRANCHING OXIDOREDUCTASEacts in the final stages of strigolactone biosynthesis inArabidopsis

(2016) Philip B. Brewer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CYP96T1 of Narcissus sp. aff. pseudonarcissus Catalyzes Formation of the Para-Para' C-C Phenol Couple in the Amaryllidaceae Alkaloids

(2016) Matthew B. Kilgore et al.   Frontiers in Plant Science

Mechanistic Insights into Taxadiene Epoxidation by Taxadiene-5α-Hydroxylase

(2015) Steven Edgar et al.   ACS Chemical Biology

Discovery and Reconstitution of the Cycloclavine Biosynthetic Pathway-Enzymatic Formation of a Cyclopropyl Group

(2015) Dorota Jakubczyk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Structural and Functional Model for the 1-Aminocyclopropane-1-carboxylic Acid Oxidase

(2015) Madleen Sallmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of a P450-catalyzed step in vindoline biosynthesis: a link between the aspidosperma and eburnamine alkaloids

(2015) Franziska Kellner et al.   CHEMICAL COMMUNICATIONS

Papaverine 7-O-demethylase, a novel 2-oxoglutarate/Fe2+-dependent dioxygenase from opium poppy

(2015) Scott C. Farrow et al.   FEBS LETTERS

Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent Oxygenases

(2015) Salette Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution and conservation of JmjC domain proteins in the green lineage

(2015) Yong Huang et al.   MOLECULAR GENETICS AND GENOMICS

Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme

(2015) Wupeng Yan et al.   NATURE

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Phytochemical genomics of the Madagascar periwinkle: Unravelling the last twists of the alkaloid engine

(2015) Thomas Dugé de Bernonville et al.   PHYTOCHEMISTRY

Expansion and Functional Divergence of Jumonji C-Containing Histone Demethylases: Significance of Duplications in Ancestral Angiosperms and Vertebrates

(2015) Shengzhan Qian et al.   PLANT PHYSIOLOGY

The Identification of Maize and Arabidopsis Type I FLAVONE SYNTHASEs Links Flavones with Hormones and Biotic Interactions

(2015) María Lorena Falcone Ferreyra et al.   PLANT PHYSIOLOGY

Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily

(2015) Kathryn M. McCulloch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone

(2015) Warren Lau et al.   SCIENCE

Structural Insights into Substrate Specificity of Feruloyl-CoA 6’-Hydroxylase from Arabidopsis thaliana

(2015) Xinxiao Sun et al.   Scientific Reports

Functional characterization of aPlagiochasma appendiculatumflavone synthase I showing flavanone 2-hydroxylase activity

(2014) Xiao-Juan Han et al.   FEBS LETTERS

Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state

(2014) Pedro Crevillén et al.   NATURE

Identification of a Unique 2-Oxoglutarate-Dependent Flavone 7-O-Demethylase Completes the Elucidation of the Lipophilic Flavone Network in Basil

(2014) Anna Berim et al.   PLANT AND CELL PHYSIOLOGY

Unexpected roles for ancient proteins: flavone 8-hydroxylase in sweet basil trichomes is a Rieske-type, PAO-family oxygenase

(2014) Anna Berim et al.   PLANT JOURNAL

Evolution and diversity of the 2-oxoglutarate-dependent dioxygenase superfamily in plants

(2014) Yosuke Kawai et al.   PLANT JOURNAL

A Simple Complex on the Verge of Breakdown: Isolation of the Elusive Cyanoformate Ion

(2014) L. J. Murphy et al.   SCIENCE

Functional diversity of 2-oxoglutarate/Fe(II)-dependent dioxygenases in plant metabolism

(2014) Scott C. Farrow et al.   Frontiers in Plant Science

4-Hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase: Exemplars of the α-keto acid dependent oxygenases

(2013) Graham R. Moran   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A Role for a Dioxygenase in Auxin Metabolism and Reproductive Development in Rice

(2013) Zhigang Zhao et al.   DEVELOPMENTAL CELL

Forensic profiling of sassafras oils based on comprehensive two-dimensional gas chromatography

(2013) M. Schäffer et al.   FORENSIC SCIENCE INTERNATIONAL

Dioxygenases CatalyzeO-Demethylation andO,O-Demethylenation with Widespread Roles in Benzylisoquinoline Alkaloid Metabolism in Opium Poppy

(2013) Scott C. Farrow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Auxin Homeostasis and Gradients in Arabidopsis Roots through the Formation of the Indole-3-Acetic Acid Catabolite 2-Oxindole-3-Acetic Acid

(2013) A. Pencik et al.   PLANT CELL

Salicylic acid 3-hydroxylase regulatesArabidopsisleaf longevity by mediating salicylic acid catabolism

(2013) Kewei Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases

(2012) WeiShen Aik et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Novel, Highly Specific N-Demethylases Enable Bacteria To Live on Caffeine and Related Purine Alkaloids

(2012) R. M. Summers et al.   JOURNAL OF BACTERIOLOGY

Enantioselective Demethylation of Nicotine as a Mechanism for Variable Nornicotine Composition in Tobacco Leaf

(2012) Bin Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

1-Aminocyclopropane-1-carboxylic acid oxidase: insight into cofactor binding from experimental and theoretical studies

(2012) Lydie Brisson et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage

(2012) Trine J. Meza et al.   NUCLEIC ACIDS RESEARCH

Norlittorine and norhyoscyamine identified as products of littorine and hyoscyamine metabolism by 13C-labeling in Datura innoxia hairy roots

(2011) Mohamad Houssam Al Balkhi et al.   PHYTOCHEMISTRY

Diversification of P450 Genes During Land Plant Evolution

(2010) Masaharu Mizutani et al.   Annual Review of Plant Biology

Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures

(2010) Isabel Desgagné-Penix et al.   BMC PLANT BIOLOGY

Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy

(2010) Jillian M Hagel et al.   Nature Chemical Biology

The nature of O2 activation by the ethylene-forming enzyme 1-aminocyclopropane-1-carboxylic acid oxidase

(2008) L. M. Mirica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA