Etoposide loaded layered double hydroxide nanoparticles reversing chemoresistance and eradicating human glioma stem cells in vitro and in vivo

Mitochondria-targetable carbon quantum dots for differentiating cancerous cells from normal cells

(2017) Ge Gao et al.   Nanoscale

pH sensitive nano layered double hydroxides reduce the hematotoxicity and enhance the anticancer efficacy of etoposide on non-small cell lung cancer

(2016) Rongrong Zhu et al.   Acta Biomaterialia

Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy

(2016) Hayley J. Paholak et al.   BIOMATERIALS

Nanomedicine-mediated cancer stem cell therapy

(2016) Song Shen et al.   BIOMATERIALS

Curcumin-Loaded Layered Double Hydroxide Nanoparticles-Induced Autophagy for Reducing Glioma Cell Migration and Invasion

(2016) Haixia Zhang et al.   Journal of Biomedical Nanotechnology

Surface charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicines

(2016) Hong-Xia Wang et al.   Nano Today

UPA-sensitive ACPP-conjugated nanoparticles for multi-targeting therapy of brain glioma

(2015) Bo Zhang et al.   BIOMATERIALS

Cancer stem cells in glioblastoma

(2015) Justin D. Lathia et al.   GENES & DEVELOPMENT

Characterization of glioma stem-like cells from human glioblastomas

(2015) SHUN YAMAMURO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Targeting delivery of etoposide to inhibit the growth of human glioblastoma multiforme using lactoferrin- and folic acid-grafted poly(lactide-co-glycolide) nanoparticles

(2015) Yung-Chih Kuo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Enhanced Anti-Metastatic Activity of Etoposide Using Layered Double Hydroxide Nano Particles

(2015) Yanjing Zhu et al.   Journal of Biomedical Nanotechnology

Layered double hydroxide nanoparticles promote self-renewal of mouse embryonic stem cells through the PI3K signaling pathway

(2015) Youjun Wu et al.   Nanoscale

Theranostic etoposide phosphate/indium nanoparticles for cancer therapy and imaging

(2015) Ramishetti Srinivas et al.   Nanoscale

Nanoparticle delivery of chemosensitizers improve chemotherapy efficacy without incurring additional toxicity

(2015) Joseph M. Caster et al.   Nanoscale

Uptake and bio-reactivity of polystyrene nanoparticles is affected by surface modifications, ageing and LPS adsorption: in vitro studies on neural tissue cells

(2015) Kumarasamy Murali et al.   Nanoscale

Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF)

(2015) B S Tan et al.   Cell Death & Disease

Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor

(2015) Ying Liu et al.   Nature Communications

Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases

(2014) Eun Jung Choi et al.   BMC CANCER

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

(2014) Mario L. Suvà et al.   CELL

Layered double hydroxide nanocomposite for drug delivery systems; bio-distribution, toxicity and drug activity enhancement

(2014) Aminu Umar Kura et al.   Chemistry Central Journal

Cell-surface Vimentin: A mislocalized protein for isolating csVimentin+CD133−novel stem-like hepatocellular carcinoma cells expressing EMT markers

(2014) Abhisek Mitra et al.   INTERNATIONAL JOURNAL OF CANCER

Excessive Hyaluronan Production Promotes Acquisition of Cancer Stem Cell Signatures through the Coordinated Regulation of Twist and the Transforming Growth Factor β (TGF-β)-Snail Signaling Axis

(2014) Theerawut Chanmee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Nanoparticles in Targeting Glioma Diagnosis and Therapies

(2014) Minghui Li et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma

(2014) A. M. Sonabend et al.   NEURO-ONCOLOGY

Targeting Cancer Stem Cell Plasticity Through Modulation of Epidermal Growth Factor and Insulin-Like Growth Factor Receptor Signaling in Head and Neck Squamous Cell Cancer

(2014) Hui Sun Leong et al.   Stem Cells Translational Medicine

Layered Double Hydroxide-Based Nanocarriers for Drug Delivery

(2014) Xue Bi et al.   Pharmaceutics

Cell surface Nestin is a biomarker for glioma stem cells

(2013) Xiong Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The in vitro sustained release profile and antitumor effect of etoposide-layered double hydroxide nanohybrids

(2013) Lili Qin et al.   International Journal of Nanomedicine

Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma

(2013) Giovanna M. Bernal et al.   Nanomedicine-Nanotechnology Biology and Medicine

Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells

(2013) Y. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resveratrol promotes proteasome-dependent degradation of Nanog via p53 activation and induces differentiation of glioma stem cells

(2013) Atsushi Sato et al.   Stem Cell Research

Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis and favors glioblastoma resistance to etoposide

(2013) D Biasoli et al.   Cell Death & Disease

Recent Advances in the Synthesis and Application of Layered Double Hydroxide (LDH) Nanosheets

(2012) Qiang Wang et al.   CHEMICAL REVIEWS

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Catalytic applications of layered double hydroxides and derivatives

(2011) Zhi Ping Xu et al.   APPLIED CLAY SCIENCE

Study of serum interaction with a cationic nanoparticle: Implications for in vitro endocytosis, cytotoxicity and genotoxicity

(2011) Maysaloun Merhi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Influence of Etoposide on anti-apoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells

(2010) Feng Jin et al.   BRAIN RESEARCH

Overexpression of CD133 Promotes Drug Resistance in C6 Glioma Cells

(2010) J. M. Angelastro et al.   MOLECULAR CANCER RESEARCH

Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion

(2010) D. Hussein et al.   NEURO-ONCOLOGY

Nanomedicine

(2010) Betty Y.S. Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma

(2010) D Meley et al.   Cell Death & Disease

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients

(2008) F. Zeppernick et al.   CLINICAL CANCER RESEARCH

Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling

(2008) Ilaria Malanchi et al.   NATURE

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

(2008) Hongwu Zheng et al.   NATURE

Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells

(2007) P. B Dirks   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES