Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF)
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF)
Authors
Keywords
-
Journal
Cell Death & Disease
Volume 6, Issue 7, Pages e1826-e1826
Publisher
Springer Nature
Online
2015-07-16
DOI
10.1038/cddis.2015.191
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine
- (2015) Claudia Fiorini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome
- (2015) Paul M. Neilsen et al. Oncotarget
- Mutant p53 in Cancer: New Functions and Therapeutic Opportunities
- (2014) Patricia A.J. Muller et al. CANCER CELL
- A common p53 mutation (R175H) activates c-Met receptor tyrosine kinase to enhance tumor cell invasion
- (2013) Katharine D Grugan et al. CANCER BIOLOGY & THERAPY
- Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9
- (2013) Jacqueline L.Y. Chee et al. CELL CYCLE
- Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis
- (2013) W Hanel et al. CELL DEATH AND DIFFERENTIATION
- Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells
- (2013) S Masciarelli et al. ONCOGENE
- Functions of TAp63 and p53 in restraining the development of metastatic cancer
- (2013) E H Tan et al. ONCOGENE
- Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression
- (2013) W Wang et al. Cell Death & Disease
- Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion
- (2012) Cynthia R Coffill et al. EMBO REPORTS
- Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature
- (2012) Hilla Solomon et al. JOURNAL OF CELL SCIENCE
- Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion
- (2012) P A J Muller et al. ONCOGENE
- Ionizing radiation induces a dramatic persistence of p53 protein accumulation and DNA damage signaling in mutant p53 zebrafish
- (2012) L Guo et al. ONCOGENE
- A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer
- (2011) Javier E. Girardini et al. CANCER CELL
- MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function
- (2011) S Donzelli et al. CELL DEATH AND DIFFERENTIATION
- Mutant p53 gain of function is interwoven into the hallmarks of cancer
- (2011) Hilla Solomon et al. JOURNAL OF PATHOLOGY
- Rapamycin synergizes cisplatin sensitivity in basal-like breast cancer cells through up-regulation of p73
- (2010) Su Wei Wong et al. BREAST CANCER RESEARCH AND TREATMENT
- BRCA1-Associated Epigenetic Regulation of p73 Mediates an Effector Pathway for Chemosensitivity in Ovarian Carcinoma
- (2010) N. Ibrahim et al. CANCER RESEARCH
- Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy
- (2010) Gianluca Bossi et al. CELL CYCLE
- Displacement of Bim by Bmf and Puma rather than increase in Bim level mediates paclitaxel-induced apoptosis in breast cancer cells
- (2010) O Kutuk et al. CELL DEATH AND DIFFERENTIATION
- The role of mutant p53 in human cancer
- (2010) Amanda M Goh et al. JOURNAL OF PATHOLOGY
- p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma
- (2010) Brendan Doyle et al. JOURNAL OF PATHOLOGY
- Mutant p53 initiates a feedback loop that involves Egr-1/EGF receptor/ERK in prostate cancer cells
- (2010) L Sauer et al. ONCOGENE
- Mutant p53 mediates survival of breast cancer cells
- (2009) L Y Lim et al. BRITISH JOURNAL OF CANCER
- Mutant p53 Drives Invasion by Promoting Integrin Recycling
- (2009) Patricia A.J. Muller et al. CELL
- A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis
- (2009) Maddalena Adorno et al. CELL
- The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis
- (2009) Giulia Fontemaggi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
- (2009) M. Olivier et al. Cold Spring Harbor Perspectives in Biology
- Suppression of Inhibitor of Differentiation 2, a Target of Mutant p53, Is Required for Gain-of-Function Mutations
- (2008) W. Yan et al. CANCER RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now