Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia

A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells

(2017) N Gunhanlar et al.   MOLECULAR PSYCHIATRY

Endoplasmic reticulum proteostasis in glioblastoma—From molecular mechanisms to therapeutic perspectives

(2017) Joanna Obacz et al.   Science Signaling

Endoplasmic reticulum proteostasis in glioblastoma—From molecular mechanisms to therapeutic perspectives

(2017) Joanna Obacz et al.   Science Signaling

Endoplasmic reticulum stress and the unfolded protein response in disorders of myelinating glia

(2016) Benjamin L.L. Clayton et al.   BRAIN RESEARCH

Reciprocal white matter alterations due to 16p11.2 chromosomal deletions versus duplications

(2016) Yi Shin Chang et al.   HUMAN BRAIN MAPPING

Myelination of parvalbumin interneurons: a parsimonious locus of pathophysiological convergence in schizophrenia

(2016) J Stedehouder et al.   MOLECULAR PSYCHIATRY

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

The implications of the shared genetics of psychiatric disorders

(2016) Michael C O'Donovan et al.   NATURE MEDICINE

Developmental timing and critical windows for the treatment of psychiatric disorders

(2016) Oscar Marín   NATURE MEDICINE

De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia

(2016) Atsushi Takata et al.   NEURON

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

(2015) Tim B. Bigdeli et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Alterations in Cortical Network Oscillations and Parvalbumin Neurons in Schizophrenia

(2015) Guillermo Gonzalez-Burgos et al.   BIOLOGICAL PSYCHIATRY

Myelination-related genes are associated with decreased white matter integrity in schizophrenia

(2015) Ivan Chavarria-Siles et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Meta-analysis of the heritability of human traits based on fifty years of twin studies

(2015) Tinca J C Polderman et al.   NATURE GENETICS

GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury

(2015) Marzieh Zonouzi et al.   NATURE NEUROSCIENCE

Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2

(2015) Fikri Birey et al.   NEURON

Oligodendrocyte Development and Plasticity

(2015) Dwight E. Bergles et al.   Cold Spring Harbor Perspectives in Biology

CSPG4-Specific Immunity and Survival Prolongation in Dogs with Oral Malignant Melanoma Immunized with Human CSPG4 DNA

(2014) F. Riccardo et al.   CLINICAL CANCER RESEARCH

The Value of Regenotyping Older Linkage Data Sets with Denser Marker Panels

(2014) Veronica J. Vieland et al.   HUMAN HEREDITY

Aberrant White Matter Microstructure in Children with 16p11.2 Deletions

(2014) J. P. Owen et al.   JOURNAL OF NEUROSCIENCE

Copy number variation in schizophrenia in Sweden

(2014) J P Szatkiewicz et al.   MOLECULAR PSYCHIATRY

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Synaptic dysregulation in a human iPS cell model of mental disorders

(2014) Zhexing Wen et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Whole-genome sequence variation, population structure and demographic history of the Dutch population

(2014) Laurent C Francioli et al.   NATURE GENETICS

Pathway Analyses Implicate Glial Cells in Schizophrenia

(2014) Laramie E. Duncan et al.   PLoS One

Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity-Dependent Ectodomain Cleavage of Glial NG2

(2014) Dominik Sakry et al.   PLOS BIOLOGY

Myelination and Oligodendrocyte Functions in Psychiatric Diseases

(2014) Klaus-Armin Nave et al.   JAMA Psychiatry

Analysis of copy number variations at 15 schizophrenia-associated loci

(2013) Elliott Rees et al.   BRITISH JOURNAL OF PSYCHIATRY

Postnatal Down-Regulation of the GABAA Receptor γ2 Subunit in Neocortical NG2 Cells Accompanies Synaptic-to-Extrasynaptic Switch in the GABAergic Transmission Mode

(2013) Maddalena Balia et al.   CEREBRAL CORTEX

T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo

(2013) C. Geldres et al.   CLINICAL CANCER RESEARCH

The Rotterdam Study: 2014 objectives and design update

(2013) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Oligodendrocyte Precursor Cells Are Accurate Sensors of Local K+ in Mature Gray Matter

(2013) P. P. Maldonado et al.   JOURNAL OF NEUROSCIENCE

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

(2013) Fadi J Najm et al.   NATURE BIOTECHNOLOGY

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Specific Glial Functions Contribute to Schizophrenia Susceptibility

(2013) A. Goudriaan et al.   SCHIZOPHRENIA BULLETIN

Abnormal Rich Club Organization and Functional Brain Dynamics in Schizophrenia

(2013) Martijn P. van den Heuvel et al.   JAMA Psychiatry

Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume

(2012) Afke F. Terwisscha van Scheltinga et al.   BIOLOGICAL PSYCHIATRY

De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia

(2012) Bin Xu et al.   NATURE GENETICS

Genetic architectures of psychiatric disorders: the emerging picture and its implications

(2012) Patrick F. Sullivan et al.   NATURE REVIEWS GENETICS

Spatial Characteristics of White Matter Abnormalities in Schizophrenia

(2012) T. White et al.   SCHIZOPHRENIA BULLETIN

Progenitor-derived Oligodendrocyte Culture System from Human Fetal Brain

(2012) Maria Chiara G. Monaco et al.   Jove-Journal of Visualized Experiments

Progressive Brain Change in Schizophrenia: A Prospective Longitudinal Study of First-Episode Schizophrenia

(2011) Nancy C. Andreasen et al.   BIOLOGICAL PSYCHIATRY

The Rotterdam Scan Study: design and update up to 2012

(2011) M. Arfan Ikram et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

On the table

(2011)   NATURE GENETICS

The Crystal Structure of the α-Neurexin-1 Extracellular Region Reveals a Hinge Point for Mediating Synaptic Adhesion and Function

(2011) Meghan T. Miller et al.   STRUCTURE

The Structure of Neurexin 1α Reveals Features Promoting a Role as Synaptic Organizer

(2011) Fang Chen et al.   STRUCTURE

Disrupted Axonal Fiber Connectivity in Schizophrenia

(2010) Andrew Zalesky et al.   BIOLOGICAL PSYCHIATRY

Diffusion tensor tractography findings in schizophrenia across the adult lifespan

(2010) Aristotle N. Voineskos et al.   BRAIN

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

A Schizophrenia Gene Locus on Chromosome 17q21 in a New Set of Families of Mexican and Central American Ancestry: Evidence From the NIMH Genetics of Schizophrenia in Latino Populations Study

(2009) Michael Escamilla et al.   AMERICAN JOURNAL OF PSYCHIATRY

Endoplasmic reticulum stress in disorders of myelinating cells

(2009) Wensheng Lin et al.   NATURE NEUROSCIENCE

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

White matter ‘potholes’ in early-onset schizophrenia: A new approach to evaluate white matter microstructure using diffusion tensor imaging

(2009) Tonya White et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Disruption of the neurexin 1 gene is associated with schizophrenia

(2008) Dan Rujescu et al.   HUMAN MOLECULAR GENETICS

White matter in learning, cognition and psychiatric disorders

(2008) R. Douglas Fields   TRENDS IN NEUROSCIENCES