The implications of the shared genetics of psychiatric disorders

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

(2016) Tarjinder Singh et al.   NATURE NEUROSCIENCE

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

(2016) Barbara Franke et al.   NATURE NEUROSCIENCE

Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia

(2016) Elliott Rees et al.   JAMA Psychiatry

Common alleles contribute to schizophrenia in CNV carriers

(2015) K E Tansey et al.   MOLECULAR PSYCHIATRY

Copy number variation in bipolar disorder

(2015) E K Green et al.   MOLECULAR PSYCHIATRY

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci

(2015) Stephan J. Sanders et al.   NEURON

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Large-scale discovery of novel genetic causes of developmental disorders

(2014) T. W. Fitzgerald et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

Most genetic risk for autism resides with common variation

(2014) Trent Gaugler et al.   NATURE GENETICS

New Approaches to Psychiatric Diagnostic Classification

(2014) Michael J. Owen   NEURON

Assessing the utility of intermediate phenotypes for genetic mapping of psychiatric disease

(2014) Jonathan Flint et al.   TRENDS IN NEUROSCIENCES

The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology

(2014) Bruce N. Cuthbert   World Psychiatry

New Ethical Issues for Genetic Counseling in Common Mental Disorders

(2013) Elliot S. Gershon et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Penetrance of Copy Number Variations for Schizophrenia and Developmental Delay

(2013) George Kirov et al.   BIOLOGICAL PSYCHIATRY

Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia

(2013) Marian L. Hamshere et al.   BRITISH JOURNAL OF PSYCHIATRY

Analysis of copy number variations at 15 schizophrenia-associated loci

(2013) Elliott Rees et al.   BRITISH JOURNAL OF PSYCHIATRY

Psychopathology and cognition in children with 22q11.2 deletion syndrome

(2013) Maria Niarchou et al.   BRITISH JOURNAL OF PSYCHIATRY

Pathogenic rare copy number variants in community-based schizophrenia suggest a potential role for clinical microarrays

(2013) G. Costain et al.   HUMAN MOLECULAR GENETICS

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

Evidence that duplications of 22q11.2 protect against schizophrenia

(2013) E Rees et al.   MOLECULAR PSYCHIATRY

CNVs conferring risk of autism or schizophrenia affect cognition in controls

(2013) Hreinn Stefansson et al.   NATURE

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

Schizoaffective Disorder in the DSM-5

(2013) Dolores Malaspina et al.   SCHIZOPHRENIA RESEARCH

Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010

(2012) Joshua A Salomon et al.   LANCET

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC

(2012) M L Hamshere et al.   MOLECULAR PSYCHIATRY

Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?

(2012) S Kapur et al.   MOLECULAR PSYCHIATRY

The Challenges and Promise of Neuroimaging in Psychiatry

(2012) David E.J. Linden   NEURON

The many faces of pleiotropy

(2012) Annalise B. Paaby et al.   TRENDS IN GENETICS

A family-based study of common polygenic variation and risk of schizophrenia

(2011) D M Ruderfer et al.   MOLECULAR PSYCHIATRY

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

(2011) G Kirov et al.   MOLECULAR PSYCHIATRY

Endophenotype: a conceptual analysis

(2010) K S Kendler et al.   MOLECULAR PSYCHIATRY

Schizophrenia

(2009) Jim van Os et al.   LANCET

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Disruption of the neurexin 1 gene is associated with schizophrenia

(2008) Dan Rujescu et al.   HUMAN MOLECULAR GENETICS