Live and let die: Hydrogen peroxide production by the commensal flora and its role in maintaining a symbiotic microbiome

Novel Two-Component System of Streptococcus sanguinis Affecting Functions Associated with Viability in Saliva and Biofilm Formation

(2018) Tarsila M. Camargo et al.   INFECTION AND IMMUNITY

Distinct Regulatory Role of Carbon Catabolite Protein A (CcpA) in Oral Streptococcal spxB Expression

(2018) Sylvio Redanz et al.   JOURNAL OF BACTERIOLOGY

Clinical concentrations of peroxidases cause dysbiosis in in vitro oral biofilms

(2018) E.R. Herrero et al.   JOURNAL OF PERIODONTAL RESEARCH

The lung tissue microbiota of mild and moderate chronic obstructive pulmonary disease

(2018) Alexa A. Pragman et al.   Microbiome

Airway microbiota across age and disease spectrum in cystic fibrosis

(2017) Edith T. Zemanick et al.   EUROPEAN RESPIRATORY JOURNAL

Role of microbial biofilms in the maintenance of oral health and in the development of dental caries and periodontal diseases. Consensus report of group 1 of the Joint EFP/ORCA workshop on the boundaries between caries and periodontal disease

(2017) Mariano Sanz et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Is SpxA2 involved in hydrogen peroxide production and competence development in Streptococcus sanguinis?

(2017) Ting Li et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Potentiation of hydrogen peroxide toxicity: From catalase inhibition to stable DNA-iron complexes

(2017) Tulip Mahaseth et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Differential oxidative stress tolerance of Streptococcus mutans isolates affects competition in an ecological mixed-species biofilm model

(2017) Yuan Liu et al.   Environmental Microbiology Reports

Comparing the Healthy Nose and Nasopharynx Microbiota Reveals Continuity As Well As Niche-Specificity

(2017) Ilke De Boeck et al.   Frontiers in Microbiology

Protective Microbiota: From Localized to Long-Reaching Co-Immunity

(2017) Lynn Chiu et al.   Frontiers in Immunology

Two-component signal transduction systems in oral bacteria

(2017) Renata O. Mattos-Graner et al.   Journal of Oral Microbiology

Biological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in Streptococcus pneumoniae D39

(2017) John P. Lisher et al.   mSphere

Metabolic Fingerprints from the Human Oral Microbiome Reveal a Vast Knowledge Gap of Secreted Small Peptidic Molecules

(2017) Anna Edlund et al.   mSystems

Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries

(2017) Daniel Belstrøm et al.   npj Biofilms and Microbiomes

Longitudinal sampling of the lung microbiota in individuals with cystic fibrosis

(2017) Fiona J. Whelan et al.   PLoS One

Streptococcus sanguinis induces neutrophil cell death by production of hydrogen peroxide

(2017) Ryuichi Sumioka et al.   PLoS One

Ecological Effect of Arginine on Oral Microbiota

(2017) Xin Zheng et al.   Scientific Reports

Fine-tuned production of hydrogen peroxide promotes biofilm formation of Streptococcus parasanguinis by a pathogenic cohabitant Aggregatibacter actinomycetemcomitans

(2016) Dingyu Duan et al.   ENVIRONMENTAL MICROBIOLOGY

Involvement of NADH Oxidase in Competition and Endocarditis Virulence in Streptococcus sanguinis

(2016) Xiuchun Ge et al.   INFECTION AND IMMUNITY

Re-evaluation of the taxonomy of the Mitis group of the genus Streptococcus based on whole genome phylogenetic analyses, and proposed reclassification of Streptococcus dentisani as Streptococcus oralis subsp. dentisani comb. nov., Streptococcus tigurinus as Streptococcus oralis subsp. tigurinus comb. nov., and Streptococcus oligofermentans as a later synonym of Streptococcus cristatus

(2016) Anders Jensen et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

l-Arginine Modifies the Exopolysaccharide Matrix and Thwarts Streptococcus mutans Outgrowth within Mixed-Species Oral Biofilms

(2016) Jinzhi He et al.   JOURNAL OF BACTERIOLOGY

Antimicrobial effects of commensal oral species are regulated by environmental factors

(2016) Esteban Rodriguez Herrero et al.   JOURNAL OF DENTISTRY

The road less traveled - defining molecular commensalism with Streptococcus sanguinis

(2016) J. Kreth et al.   Molecular Oral Microbiology

Biogeography of a human oral microbiome at the micron scale

(2016) Jessica L. Mark Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The healthy human microbiome

(2016) Jason Lloyd-Price et al.   Genome Medicine

Temporal dynamics of bacterial microbiota in the human oral cavity determined using an in situ model of dental biofilms

(2016) Nanako Wake et al.   npj Biofilms and Microbiomes

Correlation of Streptococcus mutans and Streptococcus sanguinis colonization and ex vivo hydrogen peroxide production in carious lesion-free and high caries adults

(2015) Rodrigo A. Giacaman et al.   ARCHIVES OF ORAL BIOLOGY

Characterization of the Arginolytic Microflora Provides Insights into pH Homeostasis in Human Oral Biofilms

(2015) Xuelian Huang et al.   CARIES RESEARCH

Towards Understanding Oral Health

(2015) Egija Zaura et al.   CARIES RESEARCH

Inter-Individual Differences in the Oral Bacteriome Are Greater than Intra-Day Fluctuations in Individuals

(2015) Yukuto Sato et al.   PLoS One

Streptococcus oligofermentans Inhibits Streptococcus mutans in Biofilms at Both Neutral pH and Cariogenic Conditions

(2015) Xudong Bao et al.   PLoS One

Aminoacetone oxidase fromStreptococcus oligofermentansbelongs to a new three-domain family of bacterial flavoproteins

(2014) Gianluca Molla et al.   BIOCHEMICAL JOURNAL

The Nasal and Sinus Microbiome in Health and Disease

(2014) Michael T. Wilson et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Oral Streptococci and Nitrite-Mediated Interference of Pseudomonas aeruginosa

(2014) Jessica A. Scoffield et al.   INFECTION AND IMMUNITY

Two-Component System VicRK Regulates Functions Associated with Establishment of Streptococcus sanguinis in Biofilms

(2014) Julianna J. Moraes et al.   INFECTION AND IMMUNITY

Comparison of genes required for H2O2 resistance in Streptococcus gordonii and Streptococcus sanguinis

(2014) Y. Xu et al.   MICROBIOLOGY-SGM

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Probing Oral Microbial Functionality – Expression of spxB in Plaque Samples

(2014) Lin Zhu et al.   PLoS One

Bacterial fight-and-flight responses enhance virulence in a polymicrobial infection

(2014) A. Stacy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Tissue-Dependent Hypothesis of Dental Caries

(2013) Á. Simón-Soro et al.   CARIES RESEARCH

Influence of pH on inhibition ofStreptococcus mutansbyStreptococcus oligofermentans

(2013) Ying Liu et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

The effect of arginine on oral biofilm communities

(2013) M.M. Nascimento et al.   Molecular Oral Microbiology

The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium

(2013) James A. Imlay   NATURE REVIEWS MICROBIOLOGY

Phenotypic Heterogeneity of Genomically-Diverse Isolates of Streptococcus mutans

(2013) Sara R. Palmer et al.   PLoS One

Streptococcus pneumoniae and reactive oxygen species: an unusual approach to living with radicals

(2013) Hasan Yesilkaya et al.   TRENDS IN MICROBIOLOGY

dprandsodin Streptococcus mutans Are Involved in Coexistence with S. sanguinis, and PerR Is Associated with Resistance to H2O2

(2012) Kei Fujishima et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Function of the Pyruvate Oxidase-Lactate Oxidase Cascade in Interspecies Competition between Streptococcus oligofermentans and Streptococcus mutans

(2012) Lei Liu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Regulation of neuraminidase expression in Streptococcus pneumoniae

(2012) Luciana Gualdi et al.   BMC MICROBIOLOGY

Evidence on existing caries risk assessment systems: are they predictive of future caries?

(2012) M Tellez et al.   COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY

Phylogenetic analysis supports horizontal gene transfer of l-amino acid oxidase gene in Streptococcus oligofermentans

(2012) Joseph M. Boggs et al.   INFECTION GENETICS AND EVOLUTION

Use of hydrogen peroxide as a biocide: new consideration of its mechanisms of biocidal action

(2012) E. Linley et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Prevalence of Streptococci and Increased Polymicrobial Diversity Associated with Cystic Fibrosis Patient Stability

(2012) L. M. Filkins et al.   JOURNAL OF BACTERIOLOGY

Microbial interactions in building of communities

(2012) C.J. Wright et al.   Molecular Oral Microbiology

Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology

(2012) G. Hajishengallis et al.   Molecular Oral Microbiology

The Role of Hydrogen Peroxide in Environmental Adaptation of Oral Microbial Communities

(2012) Lin Zhu et al.   Oxidative Medicine and Cellular Longevity

Role of Operon aaoSo-mutT in Antioxidant Defense in Streptococcus oligofermentans

(2012) Peng Zhou et al.   PLoS One

SpxA1 Involved in Hydrogen Peroxide Production, Stress Tolerance and Endocarditis Virulence in Streptococcus sanguinis

(2012) Lei Chen et al.   PLoS One

Unexpected tautomeric equilibria of the carbanion-enamine intermediate in pyruvate oxidase highlight unrecognized chemical versatility of thiamin

(2012) D. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental Influences on Competitive Hydrogen Peroxide Production in Streptococcus gordonii

(2011) Lanyan Zheng et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microbicidal efficacy of thiocyanate hydrogen peroxide after adding lactoperoxidase under saliva loading in the quantitative suspension test

(2011) A. Welk et al.   ARCHIVES OF ORAL BIOLOGY

Hydrogen Peroxide-Dependent DNA Release and Transfer of Antibiotic Resistance Genes in Streptococcus gordonii

(2011) A. Itzek et al.   JOURNAL OF BACTERIOLOGY

Peroxide Stimulon and Role of PerR in Group A Streptococcus

(2011) R. Grifantini et al.   JOURNAL OF BACTERIOLOGY

How is the development of dental biofilms influenced by the host?

(2011) Philip D. Marsh et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Real-time mapping of a hydrogen peroxide concentration profile across a polymicrobial bacterial biofilm using scanning electrochemical microscopy

(2011) X. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems-level analysis of microbial community organization through combinatorial labeling and spectral imaging

(2011) A. M. Valm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen dependent pyruvate oxidase expression and production in Streptococcus sanguinis

(2011) Lan‐yan Zheng et al.   International Journal of Oral Science

Metabolite Cross-Feeding Enhances Virulence in a Model Polymicrobial Infection

(2011) Matthew M. Ramsey et al.   PLoS Pathogens

Catabolite Control Protein A Controls Hydrogen Peroxide Production and Cell Death in Streptococcus sanguinis

(2010) L. Zheng et al.   JOURNAL OF BACTERIOLOGY

Identification of hydrogen peroxide production-related genes in Streptococcus sanguinis and their functional relationship with pyruvate oxidase

(2010) L. Chen et al.   MICROBIOLOGY-SGM

Talk of the town: interspecies communication in oral biofilms

(2010) N.S. Jakubovics   Molecular Oral Microbiology

Oral Biofilm Architecture on Natural Teeth

(2010) Vincent Zijnge et al.   PLoS One

The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information

(2010) T. Chen et al.   Database-The Journal of Biological Databases and Curation

Bacterial and Host Interactions of Oral Streptococci

(2009) Jens Kreth et al.   DNA AND CELL BIOLOGY

Inorganic Chemistry of Defensive Peroxidases in the Human Oral Cavity

(2009) M. T. Ashby   JOURNAL OF DENTAL RESEARCH

Influence of a model human defensive peroxidase system on oral streptococcal antagonism

(2009) M. T. Ashby et al.   MICROBIOLOGY-SGM

Polymicrobial interactions stimulate resistance to host innate immunity through metabolite perception

(2009) M. M. Ramsey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mechanisms of carbon catabolite repression in bacteria

(2008) Josef Deutscher   CURRENT OPINION IN MICROBIOLOGY

Role of hydrogen peroxide in competition and cooperation between Streptococcus gordonii and Actinomyces naeslundii

(2008) Nicholas S. Jakubovics et al.   FEMS MICROBIOLOGY ECOLOGY

An Iron-Binding Protein, Dpr, Decreases Hydrogen Peroxide Stress and Protects Streptococcus pyogenes against Multiple Stresses

(2008) C.-C. Tsou et al.   INFECTION AND IMMUNITY

Concerted Action of Lactate Oxidase and Pyruvate Oxidase in Aerobic Growth of Streptococcus pneumoniae: Role of Lactate as an Energy Source

(2008) H. Taniai et al.   JOURNAL OF BACTERIOLOGY

Streptococcal Antagonism in Oral Biofilms: Streptococcus sanguinis and Streptococcus gordonii Interference with Streptococcus mutans

(2008) J. Kreth et al.   JOURNAL OF BACTERIOLOGY

SO-LAAO, a Novel L-Amino Acid Oxidase That Enables Streptococcus oligofermentans To Outcompete Streptococcus mutans by Generating H2O2 from Peptone

(2008) H. Tong et al.   JOURNAL OF BACTERIOLOGY

Physiological heterogeneity in biofilms

(2008) Philip S. Stewart et al.   NATURE REVIEWS MICROBIOLOGY

A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients

(2008) C. D. Sibley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of sucrose in the fitness of Streptococcus mutans

(2008) J. Kreth et al.   Oral microbiology and immunology