Exogenous IL-6 induces mRNA splice variant MBD2_v2 to promote stemness in TP53 wild-type, African American PCa cells

Risk of Pathological Upgrading and Up Staging among Men with Low Risk Prostate Cancer Varies by Race: Results from the National Cancer Database

(2017) Matthew J. Maurice et al.   JOURNAL OF UROLOGY

Census and evaluation of p53 target genes

(2017) M Fischer   ONCOGENE

Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations

(2017) Franklin W. Huang et al.   Cancer Discovery

Treating triple negative breast cancer cells with erlotinib plus a select antioxidant overcomes drug resistance by targeting cancer cell heterogeneity

(2017) Bin Bao et al.   Scientific Reports

Mutational Landscape of Aggressive Prostate Tumors in African American Men

(2016) Karla J. Lindquist et al.   CANCER RESEARCH

A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors

(2016) Haihong Zhong et al.   CANCER RESEARCH

A Study ofTP53RNA Splicing Illustrates Pitfalls of RNA-seq Methodology

(2016) Sunali Mehta et al.   CANCER RESEARCH

Defining a Population of Stem-like Human Prostate Cancer Cells That Can Generate and Propagate Castration-Resistant Prostate Cancer

(2016) X. Chen et al.   CLINICAL CANCER RESEARCH

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis

(2016) Collene R Jeter et al.   Cell Discovery

Characterization of 1577 Primary Prostate Cancers Reveals Novel Biological and Clinicopathologic Insights into Molecular Subtypes

(2015) Scott A. Tomlins et al.   EUROPEAN UROLOGY

Novel Biomarker Signature That May Predict Aggressive Disease in African American Men With Prostate Cancer

(2015) Kosj Yamoah et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting JAK kinase in solid tumors: emerging opportunities and challenges

(2015) M Buchert et al.   ONCOGENE

STAT3 regulated ARF expression suppresses prostate cancer metastasis

(2015) Jan Pencik et al.   Nature Communications

A Paracrine Role for IL6 in Prostate Cancer Patients: Lack of Production by Primary or Metastatic Tumor Cells

(2015) S.-H. Yu et al.   Cancer Immunology Research

Difference in Association of Obesity With Prostate Cancer Risk Between US African American and Non-Hispanic White Men in the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

(2015) Wendy E. Barrington et al.   JAMA Oncology

Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells

(2014) Yu Lu et al.   Cell Stem Cell

Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men

(2014) F. Khani et al.   CLINICAL CANCER RESEARCH

Clinical significance of different types ofp53gene alteration in surgically treated prostate cancer

(2014) Martina Kluth et al.   INTERNATIONAL JOURNAL OF CANCER

Epidemiology, biology, and treatment of triple-negative breast cancer in women of African ancestry

(2014) Abenaa M Brewster et al.   LANCET ONCOLOGY

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Genes Associated with Prostate Cancer Are Differentially Expressed in African American and European American Men

(2013) I. J. Powell et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells

(2013) P. Kroon et al.   CANCER RESEARCH

Generation of Prostate Tumor-Initiating Cells Is Associated with Elevation of Reactive Oxygen Species and IL-6/STAT3 Signaling

(2013) Y. Qu et al.   CANCER RESEARCH

The Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate

(2013) Abby Sarkar et al.   Cell Stem Cell

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

(2013) Alessia Gagliardi et al.   EMBO JOURNAL

Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR-145

(2013) DONG REN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Re-Examining Racial Disparities in Prostate Cancer Outcomes

(2013) Matthew R. Cooperberg   JOURNAL OF CLINICAL ONCOLOGY

Minireview: The Molecular and Genomic Basis for Prostate Cancer Health Disparities

(2013) Isaac J. Powell et al.   MOLECULAR ENDOCRINOLOGY

Comparative analysis of RNA sequencing methods for degraded or low-input samples

(2013) Xian Adiconis et al.   NATURE METHODS

AZD1480: A Phase I Study of a Novel JAK2 Inhibitor in Solid Tumors

(2013) E. R. Plimack et al.   ONCOLOGIST

Socioeconomic status, healthcare density, and risk of prostate cancer among African American and Caucasian men in a large prospective study

(2012) Jacqueline M. Major et al.   CANCER CAUSES & CONTROL

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells

(2011) Adrian P. Rybak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer

(2011) K. Fizazi et al.   EUROPEAN JOURNAL OF CANCER

p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

(2011) Chun-Ju Chang et al.   NATURE CELL BIOLOGY

Prostate Cancer in Men Less Than the Age of 50: A Comparison of Race and Outcomes

(2011) Patrick M. Parker et al.   UROLOGY

Clinical and Correlative Results of SWOG S0354: A Phase II Trial of CNTO328 (Siltuximab), a Monoclonal Antibody against Interleukin-6, in Chemotherapy-Pretreated Patients with Castration-Resistant Prostate Cancer

(2010) T. B. Dorff et al.   CLINICAL CANCER RESEARCH

Evidence Supports a Faster Growth Rate and/or Earlier Transformation to Clinically Significant Prostate Cancer in Black Than in White American Men, and Influences Racial Progression and Mortality Disparity

(2010) Isaac J. Powell et al.   JOURNAL OF UROLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Gleason Score and Lethal Prostate Cancer: Does 3 + 4 = 4 + 3?

(2009) Jennifer R. Stark et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor Immunobiological Differences in Prostate Cancer between African-American and European-American Men

(2008) T. A. Wallace et al.   CANCER RESEARCH

Prostate Cancer Stem Cells: A New Target for Therapy

(2008) Norman J. Maitland et al.   JOURNAL OF CLINICAL ONCOLOGY