A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

(2013) Yael Costa et al.   NATURE

DNA-dependent Oct4–Sox2 interaction and diffusion properties characteristic of the pluripotent cell state revealed by fluorescence spectroscopy

(2012) Chen Sok Lam et al.   BIOCHEMICAL JOURNAL

O-GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network

(2012) Hyonchol Jang et al.   Cell Stem Cell

The Polycomb Group Protein L3mbtl2 Assembles an Atypical PRC1-Family Complex that Is Essential in Pluripotent Stem Cells and Early Development

(2012) Jinzhong Qin et al.   Cell Stem Cell

Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells

(2012) Nicola Festuccia et al.   Cell Stem Cell

Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

(2012) Emily Brookes et al.   Cell Stem Cell

NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment

(2012) Nicola Reynolds et al.   Cell Stem Cell

Cell-Surface Proteomics Identifies Lineage-Specific Markers of Embryo-Derived Stem Cells

(2012) Peter J. Rugg-Gunn et al.   DEVELOPMENTAL CELL

OCT4/SOX2-independentNanogautorepression modulates heterogeneousNanoggene expression in mouse ES cells

(2012) Pablo Navarro et al.   EMBO JOURNAL

Determination of Protein Interactome of Transcription Factor Sox2 in Embryonic Stem Cells Engineered for Inducible Expression of Four Reprogramming Factors

(2012) Zhiguang Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming

(2012) M. Fidalgo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-Motif Discovery Identifies an Esrrb-Sox2-DNA Ternary Complex as a Mediator of Transcriptional Differences Between Mouse Embryonic and Epiblast Stem Cells

(2012) Andrew Paul Hutchins et al.   STEM CELLS

Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation

(2011) Hiroki Ura et al.   EMBO JOURNAL

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

(2011) Erik Engelen et al.   NATURE GENETICS

GeneProf: analysis of high-throughput sequencing experiments

(2011) Florian Halbritter et al.   NATURE METHODS

Direct targets of Klf5 transcription factor contribute to the maintenance of mouse embryonic stem cell undifferentiated state

(2010) Silvia Parisi et al.   BMC BIOLOGY

An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells

(2010) Debbie L.C. van den Berg et al.   Cell Stem Cell

Polycomb Group Proteins Set the Stage for Early Lineage Commitment

(2010) Lauren E. Surface et al.   Cell Stem Cell

An Expanded Oct4 Interaction Network: Implications for Stem Cell Biology, Development, and Disease

(2010) Mercedes Pardo et al.   Cell Stem Cell

Phosphorylation stabilizes Nanog by promoting its interaction with Pin1

(2010) M. Moretto-Zita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The C-terminal Pentapeptide of Nanog Tryptophan Repeat Domain Interacts with Nac1 and Regulates Stem Cell Proliferation but Not Pluripotency

(2009) Tianhua Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

(2009) Rebecca Favaro et al.   NATURE NEUROSCIENCE

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

The pluripotency rheostat Nanog functions as a dimer

(2008) Nicholas P. Mullin et al.   BIOCHEMICAL JOURNAL

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

(2008) Jonghwan Kim et al.   CELL

Keeping things quiet: Roles of NuRD and Sin3 co-repressor complexes during mammalian development

(2008) Patrick McDonel et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

(2008) Jiancong Liang et al.   NATURE CELL BIOLOGY

Zfp143 RegulatesNanogThrough Modulation of Oct4 Binding

(2008) Xi Chen et al.   STEM CELLS

Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog

(2007) Ralf Jauch et al.   JOURNAL OF MOLECULAR BIOLOGY