Evaluation of Brain Nuclear Medicine Imaging Tracers in a Murine Model of Sepsis-Associated Encephalopathy

Neurodegenerative changes and neuroapoptosis induced by systemic lipopolysaccharide administration are reversed by dexmedetomidine treatment in mice

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Contribution of neuroinflammation to changes in [ 11 C]flumazenil binding in the rat brain: Evaluation of the inflamed pons as reference tissue

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I-123 iomazenil single photon emission computed tomography for detecting loss of neuronal integrity in patients with traumatic brain injury

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Neuroanatomy and Physiology of Brain Dysfunction in Sepsis

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Glucose consumption of inflammatory cells masks metabolic deficits in the brain

(2016) Heiko Backes et al.   NEUROIMAGE

Activation of microglial P2Y12 receptor is required for outward potassium currents in response to neuronal injury

(2016) P. Swiatkowski et al.   NEUROSCIENCE

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

(2016) Gergely Szalay et al.   Nature Communications

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GABAergic signalling in the immune system

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The dynamic cerebral autoregulatory adaptive response to noradrenaline is attenuated during systemic inflammation in humans

(2015) Ronan MG Berg et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Radiosynthesis,In VivoBiological Evaluation, and Imaging of Brain Lesions with [123I]-CLINME, a New SPECT Tracer for the Translocator Protein

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Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity

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Systemic inflammation and microglial activation: systematic review of animal experiments

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Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

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AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3

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Iodine-125-labeled cRGD-gold nanoparticles as tumor-targeted radiosensitizer and imaging agent

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Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation

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Citric Acid Effects on Brain and Liver Oxidative Stress in Lipopolysaccharide-Treated Mice

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In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse

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Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Imaging in sepsis-associated encephalopathy—insights and opportunities

(2013) Daniel J. Stubbs et al.   Nature Reviews Neurology

Bioenergetics, Mitochondrial Dysfunction, and Oxidative Stress in the Pathophysiology of Septic Encephalopathy

(2013) Fernando A. Bozza et al.   SHOCK

123 I-Iomazenil Single Photon Emission Computed Tomography Visualizes Recovery of Neuronal Integrity by Bone Marrow Stromal Cell Therapy in Rat Infarct Brain

(2013) Hisayasu Saito et al.   STROKE

Phenotyping primary human microglia: Tight regulation of LPS responsiveness

(2012) Jeroen Melief et al.   GLIA

Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4

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Species Difference of Esterase Expression and Hydrolase Activity in Plasma

(2012) Fatma Goksin Bahar et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Astrocytes as GABA-ergic and GABA-ceptive Cells

(2012) Bo-Eun Yoon et al.   NEUROCHEMICAL RESEARCH

Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates

(2012) Jonas Hannestad et al.   NEUROIMAGE

Sepsis-associated encephalopathy: not just delirium

(2011) Fernando Godinho Zampieri et al.   Clinics

GABA and GABAA receptor expression on immune cells in psoriasis: a pathophysiological role

(2010) Rishi Nigam et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Astrocytes are GABAergic cells that modulate microglial activity

(2010) Moonhee Lee et al.   GLIA

Filled and glycosylated carbon nanotubes for in vivo radioemitter localization and imaging

(2010) Sung You Hong et al.   NATURE MATERIALS

EANM procedure guideline for brain perfusion SPECT using 99mTc-labelled radiopharmaceuticals, version 2

(2009) Özlem L. Kapucu et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Role of Endothelial TLR4 for Neutrophil Recruitment into Central Nervous System Microvessels in Systemic Inflammation

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Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism

(2008) Alexander Semmler et al.   Journal of Neuroinflammation

P2Y12 Receptor Upregulation in Activated Microglia Is a Gateway of p38 Signaling and Neuropathic Pain

(2008) K. Kobayashi et al.   JOURNAL OF NEUROSCIENCE

Translocator protein 18 kDa (TSPO): Molecular sensor of brain injury and repair

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