Imaging robust microglial activation after lipopolysaccharide administration in humans with PET
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Imaging robust microglial activation after lipopolysaccharide administration in humans with PET
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112, Issue 40, Pages 12468-12473
Publisher
Proceedings of the National Academy of Sciences
Online
2015-09-19
DOI
10.1073/pnas.1511003112
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Deleterious versus protective autoimmunity in multiple sclerosis
- (2015) Milos Kostic et al. CELLULAR IMMUNOLOGY
- 11C-PBR28 imaging in multiple sclerosis patients and healthy controls: test-retest reproducibility and focal visualization of active white matter areas
- (2015) Eunkyung Park et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Can Studies of Neuroinflammation in a TSPO Genetic Subgroup (HAB or MAB) Be Applied to the Entire AD Cohort?
- (2015) Z. Fan et al. JOURNAL OF NUCLEAR MEDICINE
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- M1 and M2 immune activation in Parkinson’s Disease: Foe and ally?
- (2015) M.S. Moehle et al. NEUROSCIENCE
- Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF
- (2015) Roman Fischer et al. Oxidative Medicine and Cellular Longevity
- Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
- (2015) Carlo Condello et al. Nature Communications
- Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes
- (2015) Elaine Setiawan et al. JAMA Psychiatry
- Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971
- (2014) Paolo Zanotti-Fregonara et al. ACS Chemical Neuroscience
- The 18 kDa Translocator Protein, Microglia and Neuroinflammation
- (2014) Guo-Jun Liu et al. BRAIN PATHOLOGY
- Targeting microglia for the treatment of Alzheimer’s disease
- (2014) Patrick L McGeer et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study
- (2014) David R Owen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Translocator Protein 18 kDa Negatively Regulates Inflammation in Microglia
- (2014) Keun-Ryung Bae et al. Journal of Neuroimmune Pharmacology
- Cocaine Abuse in Humans Is Not Associated with Increased Microglial Activation: An 18-kDa Translocator Protein Positron Emission Tomography Imaging Study with [11C]PBR28
- (2014) R. Narendran et al. JOURNAL OF NEUROSCIENCE
- In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with 18F-PBR111 PET
- (2014) A. Colasanti et al. JOURNAL OF NUCLEAR MEDICINE
- Effects of Centrally Administered Etanercept on Behavior, Microglia and Astrocytes in Mice Following a Peripheral Immune Challenge
- (2014) Marie lou Camara et al. NEUROPSYCHOPHARMACOLOGY
- Transgenic Increase in n-3/n-6 Fatty Acid Ratio Protects Against Cognitive Deficits Induced by an Immune Challenge through Decrease of Neuroinflammation
- (2014) Jean-Christophe Delpech et al. NEUROPSYCHOPHARMACOLOGY
- In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease
- (2013) William C. Kreisl et al. BRAIN
- The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: A [11C]PBR28 PET study
- (2013) Jonas Hannestad et al. BRAIN BEHAVIOR AND IMMUNITY
- Endotoxin-induced experimental systemic inflammation in humans: A model to disentangle immune-to-brain communication
- (2013) Manfred Schedlowski et al. BRAIN BEHAVIOR AND IMMUNITY
- Minocycline: far beyond an antibiotic
- (2013) N Garrido-Mesa et al. BRITISH JOURNAL OF PHARMACOLOGY
- Can we switch microglia's phenotype to foster neuroprotection? Focus on multiple sclerosis
- (2013) Debora Giunti et al. IMMUNOLOGY
- Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice
- (2013) Steven Biesmans et al. MEDIATORS OF INFLAMMATION
- Microglia: New Roles for the Synaptic Stripper
- (2013) Helmut Kettenmann et al. NEURON
- Peripheral immunomodulation with ginsenoside Rg1 ameliorates neuroinflammation-induced behavioral deficits in rats
- (2013) X. Zheng et al. NEUROSCIENCE
- Inflammatory pathways of seizure disorders
- (2013) Nicola Marchi et al. TRENDS IN NEUROSCIENCES
- Animal models of sepsis
- (2013) Mitchell P Fink Virulence
- Activated microglia are implicated in cognitive deficits, neuronal death, and successful recovery following intermittent ethanol exposure
- (2012) Ya-Nan Zhao et al. BEHAVIOURAL BRAIN RESEARCH
- Microglia and neurodegeneration: The role of systemic inflammation
- (2012) Colm Cunningham GLIA
- A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation
- (2012) William C Kreisl et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study
- (2012) Sara Bromander et al. Journal of Neuroinflammation
- Glucose Metabolism in the Insula and Cingulate Is Affected by Systemic Inflammation in Humans
- (2012) J. Hannestad et al. JOURNAL OF NUCLEAR MEDICINE
- Endotoxin-induced systemic inflammation activates microglia: [11C]PBR28 positron emission tomography in nonhuman primates
- (2012) Jonas Hannestad et al. NEUROIMAGE
- Review: Activation patterns of microglia and their identification in the human brain
- (2012) D. Boche et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Neuroinflammation, Neurodegeneration, and Depression
- (2012) Laura L. Hurley et al. NEUROTOXICITY RESEARCH
- An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28
- (2011) David R Owen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Citalopram reduces endotoxin-induced fatigue
- (2010) Jonas Hannestad et al. BRAIN BEHAVIOR AND IMMUNITY
- Alcoholism and inflammation: Neuroimmunology of behavioral and mood disorders
- (2010) Keith W. Kelley et al. BRAIN BEHAVIOR AND IMMUNITY
- Immune modulation of learning, memory, neural plasticity and neurogenesis
- (2010) Raz Yirmiya et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglial alterations in human Alzheimer's disease following Aβ42 immunization
- (2010) E. Zotova et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Inflammation, microglia, and alzheimer's disease
- (2009) Brent Cameron et al. NEUROBIOLOGY OF DISEASE
- Endotoxin tolerance: new mechanisms, molecules and clinical significance
- (2009) Subhra K. Biswas et al. TRENDS IN IMMUNOLOGY
- PET Imaging of the Peripheral Benzodiazepine Receptor: Monitoring Disease Progression and Therapy Response in Neurodegenerative Disorders
- (2008) Janine Doorduin et al. CURRENT PHARMACEUTICAL DESIGN
- From inflammation to sickness and depression: when the immune system subjugates the brain
- (2007) Robert Dantzer et al. NATURE REVIEWS NEUROSCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started