Hic-5 expression is a major indicator of cancer cell morphology, migration, and plasticity in three-dimensional matrices

Hic-5 regulates fibrillar adhesion formation to control tumor extracellular matrix remodeling through interaction with tensin1

(2018) Gregory J. Goreczny et al.   ONCOGENE

Vinculin regulates directionality and cell polarity in two- and three-dimensional matrix and three-dimensional microtrack migration

(2016) Aniqua Rahman et al.   MOLECULAR BIOLOGY OF THE CELL

Epithelial-mesenchymal transition in tumor metastasis

(2016) Kay T. Yeung et al.   Molecular Oncology

Hic-5 remodeling of the stromal matrix promotes breast tumor progression

(2016) G J Goreczny et al.   ONCOGENE

Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen

(2015) Ingo Thievessen et al.   FASEB JOURNAL

Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

FilGAP, a Rac-specific Rho GTPase-activating protein, is a novel prognostic factor for follicular lymphoma

(2015) Tatsuya Nishi et al.   Cancer Medicine

How vinculin regulates force transmission

(2013) D. W. Dumbauld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells

(2012) Masato Eitaki et al.   BMC CANCER

CdGAP regulates cell migration and adhesion dynamics in two-and three-dimensional matrix environments

(2012) Duncan Wormer et al.   Cytoskeleton

Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition

(2012) Jeanine Pignatelli et al.   JOURNAL OF CELL BIOLOGY

Paxillin and Hic-5 Interaction with Vinculin Is Differentially Regulated by Rac1 and RhoA

(2012) Nicholas O. Deakin et al.   PLoS One

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

A new micropatterning method of soft substrates reveals that different tumorigenic signals can promote or reduce cell contraction levels

(2011) Qingzong Tseng et al.   LAB ON A CHIP

Rho-GTPase signaling drives melanoma cell plasticity

(2010) Victoria Sanz-Moreno et al.   CELL CYCLE

Paxillin expression and amplification in early lung lesions of high-risk patients, lung adenocarcinoma and metastatic disease

(2010) A. C. Mackinnon et al.   JOURNAL OF CLINICAL PATHOLOGY

Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis

(2010) Nicholas O. Deakin et al.   MOLECULAR BIOLOGY OF THE CELL

Emerging role of Paxillin-PKL in regulation of cell adhesion, polarity and migration

(2010) Jianxin A. Yu et al.   Cell Adhesion & Migration

The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells

(2009) K. Paňková et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

(2009) R. Grant Rowe et al.   JOURNAL OF CELL BIOLOGY

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

(2009) D Yamazaki et al.   ONCOGENE

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

DOCK10-Mediated Cdc42 Activation Is Necessary for Amoeboid Invasion of Melanoma Cells

(2008) Gilles Gadea et al.   CURRENT BIOLOGY

Paxillin comes of age

(2008) N. O. Deakin et al.   JOURNAL OF CELL SCIENCE

Stathmin Activity Influences Sarcoma Cell Shape, Motility, and Metastatic Potential

(2008) Barbara Belletti et al.   MOLECULAR BIOLOGY OF THE CELL

Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma Metastases

(2008) L. Xu et al.   MOLECULAR CANCER RESEARCH