Hic-5 remodeling of the stromal matrix promotes breast tumor progression

Focal adhesions, stress fibers and mechanical tension

(2016) Keith Burridge et al.   EXPERIMENTAL CELL RESEARCH

Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation

(2016) Scott D. Varney et al.   JOURNAL OF CELL SCIENCE

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of Hic–5 as a Novel Scaffold for the MKK4/p54 JNK Pathway in the Development of Abdominal Aortic Aneurysms

(2014) Xiao‐Feng Lei et al.   Journal of the American Heart Association

Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program

(2013) Kevin J. Cheung et al.   CELL

Regulation of cell adhesion and migration by cell-derived matrices

(2013) Matthew L. Kutys et al.   EXPERIMENTAL CELL RESEARCH

Mechanotransduction at focal adhesions: integrating cytoskeletal mechanics in migrating cells

(2013) Jean-Cheng Kuo   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Recent Developments in Myofibroblast Biology

(2012) Boris Hinz et al.   AMERICAN JOURNAL OF PATHOLOGY

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

(2012) Julia Tchou et al.   BMC Medical Genomics

Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition

(2012) Jeanine Pignatelli et al.   JOURNAL OF CELL BIOLOGY

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Paxillin and Hic-5 Interaction with Vinculin Is Differentially Regulated by Rac1 and RhoA

(2012) Nicholas O. Deakin et al.   PLoS One

Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy

(2011) R. Rezakhaniha et al.   Biomechanics and Modeling in Mechanobiology

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8

(2011) D T N Shola et al.   ONCOGENE

Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis

(2010) Nicholas O. Deakin et al.   MOLECULAR BIOLOGY OF THE CELL

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Stromal myofibroblasts are drivers of invasive cancer growth

(2008) Olivier De Wever et al.   INTERNATIONAL JOURNAL OF CANCER

Hic-5 Promotes the Hypertrophic Scar Myofibroblast Phenotype by Regulating the TGF-β1 Autocrine Loop

(2008) Ganary Dabiri et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cancer as an overhealing wound: an old hypothesis revisited

(2008) Matthias Schäfer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55

(2008) H Wang et al.   ONCOGENE