Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells

The Epidermal Growth Factor Receptor Mediates Tumor Necrosis Factor-α-induced Activation of the ERK/GEF-H1/RhoA Pathway in Tubular Epithelium

(2011) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells

(2011) Xiaohong Zhao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system

(2010) Eliza Wiercinska et al.   BREAST CANCER RESEARCH AND TREATMENT

The RhoA Activator GEF-H1/Lfc Is a Transforming Growth Factor-β Target Gene and Effector That Regulates α-Smooth Muscle Actin Expression and Cell Migration

(2010) Anna Tsapara et al.   MOLECULAR BIOLOGY OF THE CELL

Doxorubicin in Combination with a Small TGFβ Inhibitor: A Potential Novel Therapy for Metastatic Breast Cancer in Mouse Models

(2010) Abhik Bandyopadhyay et al.   PLoS One

The coordination between actin filaments and adhesion in mesenchymal migration

(2010) Geraldine M. O'Neill   Cell Adhesion & Migration

The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells

(2009) K. Paňková et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

GEF-H1 Mediates Tumor Necrosis Factor-α-induced Rho Activation and Myosin Phosphorylation

(2009) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guanine Nucleotide Exchange Factor-H1 Regulates Cell Migration via Localized Activation of RhoA at the Leading Edge

(2009) Perihan Nalbant et al.   MOLECULAR BIOLOGY OF THE CELL

Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates

(2009) D Yamazaki et al.   ONCOGENE

Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment

(2009) Lauren K. Dunn et al.   PLoS One

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

Imaging amoeboid cancer cell motilityin vivo

(2008) S. PINNER et al.   JOURNAL OF MICROSCOPY

GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

(2008) Yuan-Chen Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Up-Regulation of Rho/ROCK Signaling in Sarcoma Cells Drives Invasion and Increased Generation of Protrusive Forces

(2008) D. Rosel et al.   MOLECULAR CANCER RESEARCH

Blebs lead the way: how to migrate without lamellipodia

(2008) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants

(2008) Sarah E. James et al.   NEUROTOXICOLOGY

Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

(2008) Jörg Birkenfeld et al.   TRENDS IN CELL BIOLOGY