Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2 -deficient mice

Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers

(2015) Willscott E. Naugler et al.   GASTROENTEROLOGY

The Cholangiopathies

(2015) Konstantinos N. Lazaridis et al.   MAYO CLINIC PROCEEDINGS

Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice

(2014) Shi-Ying Cai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19

(2014) M. Zhou et al.   CANCER RESEARCH

Genomic portrait of resectable hepatocellular carcinomas: Implications ofRB1andFGF19aberrations for patient stratification

(2014) Sung-Min Ahn et al.   HEPATOLOGY

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

(2014) Iker Uriarte et al.   INTERNATIONAL JOURNAL OF CANCER

A nontumorigenic variant of FGF19 treats cholestatic liver diseases

(2014) J. Luo et al.   Science Translational Medicine

Expression of Fibroblast Growth Factor 19 Is Associated with Recurrence and Poor Prognosis of Hepatocellular Carcinoma

(2013) Jiyeon Hyeon et al.   DIGESTIVE DISEASES AND SCIENCES

Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice

(2013) Iker Uriarte et al.   GUT

Peroxisome proliferator-activated receptor α activates human multidrug resistance transporter 3/ATP-binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion

(2013) Nisanne S. Ghonem et al.   HEPATOLOGY

Circulating Fibroblast Growth Factors as Metabolic Regulators—A Critical Appraisal

(2012) Bo Angelin et al.   Cell Metabolism

Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

(2012) M. J. Potthoff et al.   GENES & DEVELOPMENT

Emerging role of fibroblast growth factors 15/19 and 21 as metabolic integrators in the liver

(2012) Claudia Cicione et al.   HEPATOLOGY

Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

(2011) Eric T. Sawey et al.   CANCER CELL

First description of ABCB4 gene deletions in familial low phospholipid-associated cholelithiasis and oral contraceptives-induced cholestasis

(2011) Eric Pasmant et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Alterations in Lipid Metabolism Mediate Inflammation, Fibrosis, and Proliferation in a Mouse Model of Chronic Cholestatic Liver Injury

(2011) Tarek Moustafa et al.   GASTROENTEROLOGY

Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2 −/− (Abcb4 −/− ) mouse cholangiopathy model by promoting biliary HCO 3− output

(2011) Anna Baghdasaryan et al.   HEPATOLOGY

The human gallbladder secretes fibroblast growth factor 19 into bile: Towards defining the role of fibroblast growth factor 19 in the enterobiliary tract

(2011) Serge J.L.B. Zweers et al.   HEPATOLOGY

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

(2010) Klementina Fon Tacer et al.   MOLECULAR ENDOCRINOLOGY

The Spectrum of Liver Diseases Related toABCB4Gene Mutations: Pathophysiology and Clinical Aspects

(2010) Anne Davit-Spraul et al.   SEMINARS IN LIVER DISEASE

High-dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis

(2009) Keith D. Lindor et al.   HEPATOLOGY

Adenovirus–Adeno-Associated Virus Hybrid for Large-Scale Recombinant Adeno-Associated Virus Production

(2009) Hongwei Zhang et al.   HUMAN GENE THERAPY

Common Variants of ABCB4 and ABCB11 and Plasma Lipid Levels: A Study in Sib Pairs with Gallstones, and Controls

(2009) Monica Acalovschi et al.   LIPIDS

ABCB4 Heterozygous Gene Mutations Associated With Fibrosing Cholestatic Liver Disease in Adults

(2008) Marianne Ziol et al.   GASTROENTEROLOGY

High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis

(2008) Frank G. Schaap et al.   HEPATOLOGY

Fifty years of advances in bile acid synthesis and metabolism

(2008) David W. Russell   JOURNAL OF LIPID RESEARCH