The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice

Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C+macrophage infiltration in mice

(2014) Christer Baeck et al.   HEPATOLOGY

Liver changes in severe Plasmodium falciparum malaria: histopathology, apoptosis and nuclear factor kappa B expression

(2014) Parnpen Viriyavejakul et al.   MALARIA JOURNAL

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis

(2014) Inmaculada Lopez-Sanchez et al.   Nature Communications

Ephrin-B2 controls PDGFR  internalization and signaling

(2013) A. Nakayama et al.   GENES & DEVELOPMENT

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

(2013) Jean-Philippe Pradere et al.   HEPATOLOGY

TNF-α/NF-κB Signaling in the CNS: Possible Connection to EPHB2

(2013) Paul D. Pozniak et al.   Journal of Neuroimmune Pharmacology

A new hypothesis on the manifestation of cerebral malaria: The secret is in the liver

(2013) Yuri Chaves Martins et al.   MEDICAL HYPOTHESES

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

TNFα-Mediated Liver Destruction by Kupffer Cells and Ly6Chi Monocytes during Entamoeba histolytica Infection

(2013) Elena Helk et al.   PLoS Pathogens

Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation

(2012) Yoshiaki Sunami et al.   HEPATOLOGY

Impact of Intravascular Hemolysis in Malaria on Liver Dysfunction

(2012) Sumanta Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFN- -Producing CD4+ T Cells Promote Experimental Cerebral Malaria by Modulating CD8+ T Cell Accumulation within the Brain

(2012) A. Villegas-Mendez et al.   JOURNAL OF IMMUNOLOGY

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

(2012) P. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Neuropathology of Fatal Cerebral Malaria in Malawian Children

(2011) Katerina Dorovini-Zis et al.   AMERICAN JOURNAL OF PATHOLOGY

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice

(2011) Felix Heymann et al.   HEPATOLOGY

Liver pathology in Malawian children with fatal encephalopathy

(2011) Richard Whitten et al.   HUMAN PATHOLOGY

High Parasite Burdens Cause Liver Damage in Mice following Plasmodium berghei ANKA Infection Independently of CD8+T Cell-Mediated Immune Pathology

(2011) Ashraful Haque et al.   INFECTION AND IMMUNITY

Chronic Hepatosplenomegaly in African School Children: A Common but Neglected Morbidity Associated with Schistosomiasis and Malaria

(2011) Shona Wilson et al.   PLoS Neglected Tropical Diseases

Endothelial Cell EphrinB2-Dependent Activation of Monocytes in Arteriosclerosis

(2010) Jennifer Braun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The fractalkine receptor CX3CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes

(2010) Karlin Raja Karlmark et al.   HEPATOLOGY

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Hepatic changes in fatal malaria: an emerging problem

(2009) A. B. Rupani et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

(2009) Karlin Raja Karlmark et al.   HEPATOLOGY

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL

Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes

(2008) D. Pfaff et al.   JOURNAL OF CELL SCIENCE

Moving targets: cell migration inhibitors as new anti-inflammatory therapies

(2008) Charles R Mackay   NATURE IMMUNOLOGY

Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro

(2008) Barden Chan et al.   THROMBOSIS RESEARCH

Chemokine-directed immune cell infiltration in acute and chronic liver disease

(2008) Karlin Raja Karlmark et al.   Expert Review of Gastroenterology & Hepatology

EphA and ephrin-A proteins regulate integrin-mediated T lymphocyte interactions

(2007) Nigel Sharfe et al.   MOLECULAR IMMUNOLOGY