NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer

TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells

(2015) Y Mu et al.   BRITISH JOURNAL OF CANCER

eIF2α phosphorylation as a biomarker of immunogenic cell death

(2015) Oliver Kepp et al.   SEMINARS IN CANCER BIOLOGY

Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells

(2013) Chia-Lin Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic Methylation of Numb by Set8 Regulates Its Binding to p53 and Apoptosis

(2013) Gurpreet Kaur Dhami et al.   MOLECULAR CELL

The p53–PUMA axis suppresses iPSC generation

(2013) Yanxin Li et al.   Nature Communications

Role of BMI1, a Stem Cell Factor, in Cancer Recurrence and Chemoresistance: Preclinical and Clinical Evidences

(2012) Hifzur Rahman Siddique et al.   STEM CELLS

Embryonic NANOG Activity Defines Colorectal Cancer Stem Cells and Modulates through AP1- and TCF-dependent Mechanisms

(2012) Elsayed E. Ibrahim et al.   STEM CELLS

p53 regulation by ubiquitin

(2011) Christopher L. Brooks et al.   FEBS LETTERS

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

(2011) H Nikki March et al.   NATURE GENETICS

Reciprocal repression between P53 and TCTP

(2011) Robert Amson et al.   NATURE MEDICINE

Receptors, Signaling Networks, and Disease

(2011) N. Cuesta et al.   Science Signaling

Functional Identification of Tumor-Suppressor Genes through an In Vivo RNA Interference Screen in a Mouse Lymphoma Model

(2009) Anka Bric et al.   CANCER CELL

p53: A New Kingpin in the Stem Cell Arena

(2009) Samuel Aparicio et al.   CELL

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization

(2008) Frederik Wirtz-Peitz et al.   CELL

NUMB controls p53 tumour suppressor activity

(2008) Ivan N. Colaluca et al.   NATURE

A role for Numb in p53 stabilization

(2008) Stephanie Carter et al.   GENOME BIOLOGY