Embryonic NANOG Activity Defines Colorectal Cancer Stem Cells and Modulates through AP1- and TCF-dependent Mechanisms

A Tcf/Lef element within the enhancer region of the human NANOG gene plays a role in promoter activation

(2011) Chang Gun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential expression of nanog1 and nanogp8 in colon cancer cells

(2011) Tatsuya Ishiguro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

OCT4 spliced variant OCT4B1 is expressed in human colorectal cancer

(2011) Maria Gazouli et al.   MOLECULAR CARCINOGENESIS

Notch post-translationally regulates β-catenin protein in stem and progenitor cells

(2011) Chulan Kwon et al.   NATURE CELL BIOLOGY

NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation

(2011) C R Jeter et al.   ONCOGENE

Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer

(2010) Hui-Min Meng et al.   CANCER BIOLOGY & THERAPY

Hedgehog controls neural stem cells through p53-independent regulation of Nanog

(2010) Agnese Po et al.   EMBO JOURNAL

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

(2010) Marie Zbinden et al.   EMBO JOURNAL

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

(2010) Frédéric Varnat et al.   EMBO Molecular Medicine

Atypical expression and distribution of embryonic stem cell marker, OCT4, in human lung adenocarcinoma

(2010) Golnaz Karoubi et al.   JOURNAL OF SURGICAL ONCOLOGY

O2 regulates stem cells through Wnt/β-catenin signalling

(2010) Jolly Mazumdar et al.   NATURE CELL BIOLOGY

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells

(2010) Irina Eberle et al.   NUCLEIC ACIDS RESEARCH

Two new protocols to enhance the production and isolation of human induced pluripotent stem cell lines

(2010) Emily Dick et al.   Stem Cell Research

Comprehensive Analysis of the Clinical Significance of Inducing Pluripotent Stemness-Related Gene Expression in Colorectal Cancer Cells

(2009) Yasumitsu Saiki et al.   ANNALS OF SURGICAL ONCOLOGY

Role of the Murine Reprogramming Factors in the Induction of Pluripotency

(2009) Rupa Sridharan et al.   CELL

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

(2009) Frédéric Varnat et al.   EMBO Molecular Medicine

The Links between Transcription,  -catenin/JNK Signaling, and Carcinogenesis

(2009) A. Saadeddin et al.   MOLECULAR CANCER RESEARCH

Defined factors induce reprogramming of gastrointestinal cancer cells

(2009) N. Miyoshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Evidence that the Self-Renewal GeneNANOGRegulates Human Tumor Development

(2009) Collene R. Jeter et al.   STEM CELLS

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

(2008) David J. Wong et al.   Cell Stem Cell

NANOG Is a Direct Target of TGFβ/Activin-Mediated SMAD Signaling in Human ESCs

(2008) Ren-He Xu et al.   Cell Stem Cell

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS