Variations in serum sphingolipid levels associate with liver fibrosis progression and poor treatment outcome in hepatitis C virus but not hepatitis B virus infection

Serum acid sphingomyelinase is upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease

(2014) Georgios Grammatikos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ceramides and cardiac function in children with chronic kidney disease

(2014) Mark Mitsnefes et al.   PEDIATRIC NEPHROLOGY

Inhibition of CeramideDe NovoSynthesis with Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes

(2014) Krzysztof Kurek et al.   Biomed Research International

A Serine Palmitoyltransferase Inhibitor Blocks Hepatitis C Virus Replication in Human Hepatocytes

(2013) Asao Katsume et al.   GASTROENTEROLOGY

The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS

(2013) Daniela Hartmann et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ablation of Ceramide Synthase 2 Causes Chronic Oxidative Stress Due to Disruption of the Mitochondrial Respiratory Chain

(2013) Hila Zigdon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Report from a Viral Hepatitis Policy Forum on implementing the WHO framework for global action on viral hepatitis in North Asia

(2013) Ding-Shinn Chen et al.   JOURNAL OF HEPATOLOGY

Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipidN-acyl chain

(2013) Sandra N. Pinto et al.   JOURNAL OF LIPID RESEARCH

Sphingosine-1-phosphate: A Janus-faced mediator of fibrotic diseases

(2012) Stephanie Schwalm et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes

(2012) Joo-Won Park et al.   HEPATOLOGY

Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth

(2012) Daniela Hartmann et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes

(2012) Sarah Brice Russo et al.   JOURNAL OF CLINICAL INVESTIGATION

The Roles of Neutral Sphingomyelinases in Neurological Pathologies

(2012) Charles R. Horres et al.   NEUROCHEMICAL RESEARCH

Serum ceramides increase the risk of Alzheimer disease: The Women's Health and Aging Study II

(2012) M. M. Mielke et al.   NEUROLOGY

Role of ceramides in nonalcoholic fatty liver disease

(2012) Mangesh Pagadala et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Self-Enhancement of Hepatitis C Virus Replication by Promotion of Specific Sphingolipid Biosynthesis

(2012) Yuichi Hirata et al.   PLoS Pathogens

Improved Responses to Pegylated Interferon Alfa-2b and Ribavirin by Individualizing Treatment for 24–72 Weeks

(2011) Christoph Sarrazin et al.   GASTROENTEROLOGY

Host sphingolipid biosynthesis is a promising therapeutic target for the inhibition of hepatitis B virus replication

(2011) Kanako Tatematsu et al.   JOURNAL OF MEDICAL VIROLOGY

Comprehensive proteomic analysis of host cell lipid rafts modified by HBV infection

(2011) Na Xie et al.   Journal of Proteomics

Hepatocytes Traffic and Export Hepatitis B Virus Basolaterally by Polarity-Dependent Mechanisms

(2011) P. Bhat et al.   JOURNAL OF VIROLOGY

Chain length-specific properties of ceramides

(2011) Sabine Grösch et al.   PROGRESS IN LIPID RESEARCH

Hepatitis c virus and host cell lipids: An intimate connection

(2011) Gualtiero Alvisi et al.   RNA Biology

Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C

(2010) Hitoshi Ikeda et al.   CLINICA CHIMICA ACTA

A Critical Role for Ceramide Synthase 2 in Liver Homeostasis

(2010) Yael Pewzner-Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood sphingolipidomics in healthy humans: impact of sample collection methodology

(2010) Samar M. Hammad et al.   JOURNAL OF LIPID RESEARCH

Gene Expression Profiling Indicates the Roles of Host Oxidative Stress, Apoptosis, Lipid Metabolism, and Intracellular Transport Genes in the Replication of Hepatitis C Virus

(2010) S. Blackham et al.   JOURNAL OF VIROLOGY

Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics

(2010) Deborah L. Diamond et al.   PLoS Pathogens

Lipids as targets for novel anti-inflammatory therapies

(2009) Andrea Huwiler et al.   PHARMACOLOGY & THERAPEUTICS

Hepatitis C virus hijacks host lipid metabolism

(2009) Gulam H. Syed et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

(2008) J. M. Haus et al.   DIABETES

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Non-invasive evaluation of liver fibrosis using transient elastography

(2008) Laurent Castera et al.   JOURNAL OF HEPATOLOGY

Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection

(2008) H. Aizaki et al.   JOURNAL OF VIROLOGY

Ceramide enrichment of the plasma membrane induces CD81 internalization and inhibits hepatitis C virus entry

(2007) Cécile Voisset et al.   CELLULAR MICROBIOLOGY