Global DNA methylation and hydroxymethylation differ in hepatocellular carcinoma and cholangiocarcinoma and relate to survival rate

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

(2015) Michael Christoph Haffner et al.   Oncotarget

Aging and Alcohol Interact to Alter Hepatic DNA Hydroxymethylation

(2014) Stephanie A. Tammen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Epigenetics in hepatocellular carcinoma: An update and future therapy perspectives

(2014) Li Ma   WORLD JOURNAL OF GASTROENTEROLOGY

Global DNA Hypomethylation in Peripheral Blood Mononuclear Cells as a Biomarker of Cancer Risk

(2013) S. Friso et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Quantification of 5-Methylcytosine and 5-Hydroxymethylcytosine in Genomic DNA from Hepatocellular Carcinoma Tissues by Capillary Hydrophilic-Interaction Liquid Chromatography/Quadrupole TOF Mass Spectrometry

(2013) M.-L. Chen et al.   CLINICAL CHEMISTRY

Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway

(2013) Benjamin Goeppert et al.   HEPATOLOGY

TET enzymes, TDG and the dynamics of DNA demethylation

(2013) Rahul M. Kohli et al.   NATURE

Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1

(2013) Chungang Liu et al.   PLoS One

Unique Association between Global DNA Hypomethylation and Chromosomal Alterations in Human Hepatocellular Carcinoma

(2013) Naoshi Nishida et al.   PLoS One

5-hydroxymethylcytosine and its potential roles in development and cancer

(2013) Gerd P Pfeifer et al.   Epigenetics & Chromatin

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Genome-wide DNA methylation profiles in hepatocellular carcinoma

(2012) Jing Shen et al.   HEPATOLOGY

Cholangiocarcinomas can originate from hepatocytes in mice

(2012) Biao Fan et al.   JOURNAL OF CLINICAL INVESTIGATION

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

(2012) Sayaka Sekiya et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

(2012) P Wang et al.   ONCOGENE

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

(2012) H Yang et al.   ONCOGENE

5-Hydroxymethylcytosine, the Sixth Base of the Genome

(2011) Martin Münzel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations

(2011) S.-G. Jin et al.   CANCER RESEARCH

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

(2011) C. E. Nestor et al.   GENOME RESEARCH

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Clinical implications of DNA methylation in hepatocellular carcinoma

(2011) Eric L. Sceusi et al.   HPB

Hepatocellular Carcinoma (HCC)

(2010) Peter Ferenci et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Prognostic Implications of and Relationship Between CpG Island Hypermethylation and Repetitive DNA Hypomethylation in Hepatocellular Carcinoma

(2009) H. S. Lee et al.   CLINICAL CANCER RESEARCH

Burden of Digestive Diseases in the United States Part III: Liver, Biliary Tract, and Pancreas

(2009) James E. Everhart et al.   GASTROENTEROLOGY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

CpG island hypermethylation and repetitive DNA hypomethylation in premalignant lesion of extrahepatic cholangiocarcinoma

(2009) Baek-hui Kim et al.   VIRCHOWS ARCHIV

Pathology of peripheral intrahepatic cholangiocarcinoma with reference to tumorigenesis

(2008) Yasuni Nakanuma et al.   HEPATOLOGY RESEARCH