Tetrathiomolybdate inhibits the reaction of cisplatin with human copper chaperone Atox1

Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin

(2016) Cristine L. Chisholm et al.   Oncotarget

XAS Investigation of Silver(I) Coordination in Copper(I) Biological Binding Sites

(2015) Giulia Veronesi et al.   INORGANIC CHEMISTRY

Tetrathiomolybdate mediates cisplatin-induced p38 signaling and EGFR degradation and enhances response to cisplatin therapy in gynecologic cancers

(2015) Kyu Kwang Kim et al.   Scientific Reports

Transporting platinum drugs from a copper chaperone to ATPase: the mechanistic implication of drug efflux mediated cisplatin resistance

(2014) Dechen Xu et al.   Inorganic Chemistry Frontiers

Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification

(2013) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1

(2013) Zhaoyong Xi et al.   CHEMICAL COMMUNICATIONS

Reaction of platinum anticancer drugs and drug derivatives with a copper transporting protein, Atox1

(2012) Maria E. Palm-Espling et al.   BIOCHEMICAL PHARMACOLOGY

The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin

(2012) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Distorted copper homeostasis with decreased sensitivity to cisplatin upon chaperone Atox1 deletion in Drosophila

(2011) Haiqing Hua et al.   BIOMETALS

Probing the Interaction of Cisplatin with the Human Copper Chaperone Atox1 by Solution and In-Cell NMR Spectroscopy

(2011) Fabio Arnesano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro

(2011) M. E. Palm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing Tumor-Specific Uptake of the Anticancer Drug Cisplatin with a Copper Chelator

(2010) Seiko Ishida et al.   CANCER CELL

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

The soluble metal-binding domain of the copper transporter ATP7B binds and detoxifies cisplatin

(2009) Nataliya V. Dolgova et al.   BIOCHEMICAL JOURNAL

Tracing Copper−Thiomolybdate Complexes in a Prospective Treatment for Wilson’s Disease†

(2009) Limei Zhang et al.   BIOCHEMISTRY

Therapeutic Targeting of ATP7B in Ovarian Carcinoma

(2009) L. S. Mangala et al.   CLINICAL CANCER RESEARCH

Crystal Structures of Cisplatin Bound to a Human Copper Chaperone

(2009) Amie K. Boal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrathiomolybdate Inhibits Copper Trafficking Proteins Through Metal Cluster Formation

(2009) H. M. Alvarez et al.   SCIENCE

Treatment of Wilson's disease with tetrathiomolybdate: V. control of free copper by tetrathiomolybdate and a comparison with trientine

(2009) George J. Brewer et al.   Translational Research

Effects of the loss of Atox1 on the cellular pharmacology of cisplatin

(2008) Roohangiz Safaei et al.   JOURNAL OF INORGANIC BIOCHEMISTRY