Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action
Authors
Keywords
-
Journal
Metallomics
Volume 10, Issue 1, Pages 93-107
Publisher
Royal Society of Chemistry (RSC)
Online
2017-11-13
DOI
10.1039/c7mt00242d
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress
- (2017) Peter M Bruno et al. NATURE MEDICINE
- Discovery of piperlongumine as a potential novel lead for the development of senolytic agents
- (2016) Yingying Wang et al. Aging-US
- Screening out irrelevant cell-based models of disease
- (2016) Peter Horvath et al. NATURE REVIEWS DRUG DISCOVERY
- Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation
- (2015) Isolda Romero-Canelón et al. JOURNAL OF MEDICINAL CHEMISTRY
- Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells
- (2015) Jessica M. Hearn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Organoiridium Complexes: Anticancer Agents and Catalysts
- (2014) Zhe Liu et al. ACCOUNTS OF CHEMICAL RESEARCH
- The Potent Oxidant Anticancer Activity of Organoiridium Catalysts
- (2014) Zhe Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mitochondrial DNA copy number and future risk of B-cell lymphoma in a nested case-control study in the prospective EPIC cohort
- (2014) F. S. Hosnijeh et al. BLOOD
- Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors
- (2014) C Wichmann et al. LEUKEMIA
- Potent organometallic osmium compounds induce mitochondria-mediated apoptosis and S-phase cell cycle arrest in A549 non-small cell lung cancer cells
- (2014) Sabine H. van Rijt et al. Metallomics
- Mechanism of cellular accumulation of an iridium(iii) pentamethylcyclopentadienyl anticancer complex containing a C,N-chelating ligand
- (2014) Vojtech Novohradsky et al. Metallomics
- Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis
- (2013) Jessica M. Hearn et al. ACS Chemical Biology
- Exploration of the medical periodic table: towards new targets
- (2013) Nicolas P. E. Barry et al. CHEMICAL COMMUNICATIONS
- Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin
- (2013) F. Stephen Hodi et al. JOURNAL OF CLINICAL ONCOLOGY
- DNA damage by reactive species: Mechanisms, mutation and repair
- (2012) N R Jena JOURNAL OF BIOSCIENCES
- Classification of mitocans, anti-cancer drugs acting on mitochondria
- (2012) Jiri Neuzil et al. MITOCHONDRION
- Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
- (2012) Wanjuan Yang et al. NUCLEIC ACIDS RESEARCH
- Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
- (2011) S. I. Grivennikov et al. ANNALS OF THE RHEUMATIC DISEASES
- Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity
- (2011) Ying Fu et al. DALTON TRANSACTIONS
- Contrasting Reactivity and Cancer Cell Cytotoxicity of Isoelectronic Organometallic Iridium(III) Complexes
- (2011) Zhe Liu et al. INORGANIC CHEMISTRY
- Organometallic Half-Sandwich Iridium Anticancer Complexes
- (2011) Zhe Liu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Selective killing of cancer cells by a small molecule targeting the stress response to ROS
- (2011) Lakshmi Raj et al. NATURE
- Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase–Bim axis and reveals glutathione-S-transferase P1 as Achilles’ heel
- (2011) D Sidler et al. ONCOGENE
- Molecular mechanisms of cisplatin resistance
- (2011) L Galluzzi et al. ONCOGENE
- Organometallic Iridium(III) Cyclopentadienyl Anticancer Complexes Containing C,N-Chelating Ligands
- (2011) Zhe Liu et al. ORGANOMETALLICS
- Organometallic Osmium Arene Complexes with Potent Cancer Cell Cytotoxicity
- (2010) Ying Fu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Irinotecan and its active metabolite, SN-38: review of bioanalytical methods and recent update from clinical pharmacology perspectives
- (2009) Mullangi Ramesh et al. BIOMEDICAL CHROMATOGRAPHY
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009
- (2008) G Kroemer et al. CELL DEATH AND DIFFERENTIATION
- DNA Interactions of Monofunctional Organometallic Osmium(II) Antitumor Complexes in Cell-Free Media
- (2008) Hana Kostrhunova et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
- (2008) Claire Henchcliffe et al. Nature clinical practice. Neurology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started