CRP Stimulates GDF15 Expression in Endothelial Cells through p53

Circulating GDF-15 levels predict future secondary manifestations of cardiovascular disease explicitly in women but not men with atherosclerosis

(2017) Aisha Gohar et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15

(2017) Jer-Yuan Hsu et al.   NATURE

GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand

(2017) Linda Yang et al.   NATURE MEDICINE

GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

(2017) Shannon E Mullican et al.   NATURE MEDICINE

The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL

(2017) Paul J Emmerson et al.   NATURE MEDICINE

p53 regulates the cardiac transcriptome

(2017) Tak W. Mak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single and multiple cardiovascular biomarkers in subjects without a previous cardiovascular event

(2017) Manan Pareek et al.   European Journal of Preventive Cardiology

Growth Differentiation Factor 15 as a Biomarker in Cardiovascular Disease

(2016) Kai C. Wollert et al.   CLINICAL CHEMISTRY

Growth Differentiation Factor 15 Predicts All-Cause Morbidity and Mortality in Stable Coronary Heart Disease

(2016) Emil Hagström et al.   CLINICAL CHEMISTRY

Protective Effects of BDNF against C-Reactive Protein-Induced Inflammation in Women

(2015) Nicole Noren Hooten et al.   MEDIATORS OF INFLAMMATION

Posttranscriptional Regulation of the Inflammatory Marker C-Reactive Protein by the RNA-Binding Protein HuR and MicroRNA 637

(2015) Yoonseo Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective

(2015) Ramu Adela et al.   Journal of Diabetes Research

Growth Differentiation Factor 15, a Marker of Oxidative Stress and Inflammation, for Risk Assessment in Patients With Atrial Fibrillation

(2014) Lars Wallentin et al.   CIRCULATION

C-reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B-cell translocation gene 2 expression

(2014) Yuna Kim et al.   FEBS LETTERS

Increased serum levels of GDF-15 associated with mortality and subclinical atherosclerosis in patients on maintenance hemodialysis

(2014) H. Yilmaz et al.   HERZ

Trends in C-Reactive Protein Levels in US Adults From 1999 to 2010

(2013) K. L. Ong et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Change in Growth Differentiation Factor 15 Concentrations over Time Independently Predicts Mortality in Community-Dwelling Elderly Individuals

(2013) K. M. Eggers et al.   CLINICAL CHEMISTRY

Adaptive Induction of Growth Differentiation Factor 15 Attenuates Endothelial Cell Apoptosis in Response to High Glucose Stimulus

(2013) Jun Li et al.   PLoS One

Association of Oxidative DNA Damage and C-Reactive Protein in Women at Risk for Cardiovascular Disease

(2012) Nicole Noren Hooten et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

C-reactive protein induces p53-mediated cell cycle arrest in H9c2 cardiac myocytes

(2011) Ji-Won Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Growth-Differentiation Factor-15 Is a Robust, Independent Predictor of 11-Year Mortality Risk in Community-Dwelling Older Adults

(2011) Lori B. Daniels et al.   CIRCULATION

GDF-15 promotes angiogenesis through modulating p53/HIF-1α signaling pathway in hypoxic human umbilical vein endothelial cells

(2011) Hejian Song et al.   MOLECULAR BIOLOGY REPORTS

Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality

(2010) Fredrik E. Wiklund et al.   AGING CELL

C-reactive protein is a mediator of cardiovascular disease

(2010) R. J. Bisoendial et al.   EUROPEAN HEART JOURNAL

MCC-555-induced NAG-1 expression is mediated in part by KLF4

(2010) Maria Cekanova et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Growth-Differentiation Factor-15 for Risk Stratification in Patients With Stable and Unstable Coronary Heart Disease

(2009) Tibor Kempf et al.   Circulation-Cardiovascular Genetics

Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells

(2008) Jae Hyeong Kim et al.   CANCER LETTERS

Influence of postprandial triglyceride-rich lipoproteins on lipid-mediated gene expression in smooth muscle cells of the human coronary artery

(2008) B. Bermudez et al.   CARDIOVASCULAR RESEARCH

Identification of Macrophage Inhibitory Cytokine-1 in Adipose Tissue and Its Secretion as an Adipokine by Human Adipocytes

(2008) Qi Ding et al.   ENDOCRINOLOGY

Nonsteroidal Anti-inflammatory Drug-activated Gene (NAG-1/GDF15) Expression Is Increased by the Histone Deacetylase Inhibitor Trichostatin A

(2008) Hiroki Yoshioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor α, on human monocytes

(2008) Armelle Ropars et al.   THROMBOSIS AND HAEMOSTASIS