Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia

Sarcopenia: An Overview on Current Definitions, Diagnosis and Treatment

(2018) Francesco Landi et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders

(2018) Anna Picca et al.   REJUVENATION RESEARCH

Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women

(2017) J Most et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Altered mitochondrial quality control signaling in muscle of old gastric cancer patients with cachexia

(2017) Emanuele Marzetti et al.   EXPERIMENTAL GERONTOLOGY

Fueling Inflamm-Aging through Mitochondrial Dysfunction: Mechanisms and Molecular Targets

(2017) Anna Picca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Gut Microbiota and Alzheimer’s Disease

(2017) Chunmei Jiang et al.   JOURNAL OF ALZHEIMERS DISEASE

Assessment of Common and Emerging Bioinformatics Pipelines for Targeted Metagenomics

(2017) Léa Siegwald et al.   PLoS One

The Gut Microbiota and Autism Spectrum Disorders

(2017) Qinrui Li et al.   Frontiers in Cellular Neuroscience

Exercise and Protein Intake: A Synergistic Approach against Sarcopenia

(2017) Anna Maria Martone et al.   Biomed Research International

Gut Microbiota Modulation and Its Relationship with Obesity Using Prebiotic Fibers and Probiotics: A Review

(2017) Dinesh K. Dahiya et al.   Frontiers in Microbiology

Two distinct metacommunities characterize the gut microbiota in Crohn's disease patients

(2017) Qing He et al.   GigaScience

A Review of Bioinformatics Tools for Bio-Prospecting from Metagenomic Sequence Data

(2017) Despoina D. Roumpeka et al.   Frontiers in Genetics

Gut microbiota composition is associated with polypharmacy in elderly hospitalized patients

(2017) Andrea Ticinesi et al.   Scientific Reports

Acrolein increases macrophage atherogenicity in association with gut microbiota remodeling in atherosclerotic mice: protective role for the polyphenol-rich pomegranate juice

(2016) Oren Rom et al.   ARCHIVES OF TOXICOLOGY

Microbial perturbations and modulation in conditions associated with malnutrition and malabsorption

(2016) Daisy M.A.E. Jonkers   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Probiotics and microbiota composition

(2016) Mary Ellen Sanders   BMC Medicine

Prebiotics: why definitions matter

(2016) Robert W Hutkins et al.   CURRENT OPINION IN BIOTECHNOLOGY

Microbiota and aging

(2016) Stephan C. Bischoff   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The geriatric management of frailty as paradigm of “The end of the disease era”

(2016) Matteo Cesari et al.   European Journal of Internal Medicine

Metagenomics, Metatranscriptomics, and Metabolomics Approaches for Microbiome Analysis

(2016) Vanessa Aguiar-Pulido et al.   Evolutionary Bioinformatics

Association between myocyte quality control signaling and sarcopenia in old hip-fractured patients: Results from the Sarcopenia in HIp FracTure (SHIFT) exploratory study

(2016) Emanuele Marzetti et al.   EXPERIMENTAL GERONTOLOGY

Impaired mitochondrial degradation by autophagy in the skeletal muscle of the aged female interleukin 10 null mouse

(2016) Fred Ko et al.   EXPERIMENTAL GERONTOLOGY

Effect of a Prebiotic Formulation on Frailty Syndrome: A Randomized, Double-Blind Clinical Trial

(2016) Cristina Buigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Manipulation of Rumen Microbial Fermentation by Polyphenol Rich Solvent Fractions from Papaya Leaf to Reduce Green-House Gas Methane and Biohydrogenation of C18 PUFA

(2016) Saeid Jafari et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Probiotics, gut microbiota, and their influence on host health and disease

(2016) Borja Sánchez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

(2016) Alexandra Zhernakova et al.   SCIENCE

Cytokine Signaling in Skeletal Muscle Wasting

(2016) Jin Zhou et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Gut Microbiome and Obesity

(2016) George Kunnackal John et al.   Current Oncology Reports

Lactobacillus plantarum TWK10 Supplementation Improves Exercise Performance and Increases Muscle Mass in Mice

(2016) Yi-Ming Chen et al.   Nutrients

Anti-inflammaging effects of Lactobacillus brevis OW38 in aged mice

(2016) J.-J. Jeong et al.   Beneficial Microbes

Making sense of big data in health research: Towards an EU action plan

(2016) Charles Auffray et al.   Genome Medicine

Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions

(2016) Linda S. Zhang et al.   Genome Medicine

Next-generation sequencing revolution through big data analytics

(2016) Rashmi Tripathi et al.   Frontiers in Life Science

Characterization of the Gut Microbiome Using 16S or Shotgun Metagenomics

(2016) Juan Jovel et al.   Frontiers in Microbiology

The Gut Microbiota in Immune-Mediated Inflammatory Diseases

(2016) Jessica D. Forbes et al.   Frontiers in Microbiology

Lifestyle and geographic insights into the distinct gut microbiota in elderly women from two different geographic locations

(2016) Ji-Hee Shin et al.   Journal of Physiological Anthropology

Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome

(2016) Hailiang Xie et al.   Cell Systems

Oral Administration of Lactobacillus plantarum HY7714 Protects Hairless Mouse Against Ultraviolet B-Induced Photoaging

(2016) Hyun Mee Kim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Piphillin: Improved Prediction of Metagenomic Content by Direct Inference from Human Microbiomes

(2016) Shoko Iwai et al.   PLoS One

Accurate binning of metagenomic contigs via automated clustering sequences using information of genomic signatures and marker genes

(2016) Hsin-Hung Lin et al.   Scientific Reports

The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

(2015) Michael E. Walsh et al.   AGING CELL

A two-phase binning algorithm using l-mer frequency on groups of non-overlapping reads

(2015) Le Vinh et al.   Algorithms for Molecular Biology

Tax4Fun: predicting functional profiles from metagenomic 16S rRNA data: Fig. 1.

(2015) Kathrin P. Aßhauer et al.   BIOINFORMATICS

CLARK: fast and accurate classification of metagenomic and genomic sequences using discriminative k-mers

(2015) Rachid Ounit et al.   BMC GENOMICS

Influence of galacto-oligosaccharide mixture (B-GOS) on gut microbiota, immune parameters and metabonomics in elderly persons

(2015) Jelena Vulevic et al.   BRITISH JOURNAL OF NUTRITION

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

(2015) Saeed Shoaie et al.   Cell Metabolism

Risk and Safety of Probiotics

(2015) Shira Doron et al.   CLINICAL INFECTIOUS DISEASES

Endotoxin-induced skeletal muscle wasting is prevented by angiotensin-(1–7) through a p38 MAPK-dependent mechanism

(2015) María Gabriela Morales et al.   CLINICAL SCIENCE

The gut microbiome in health and in disease

(2015) Andrew B. Shreiner et al.   CURRENT OPINION IN GASTROENTEROLOGY

Synbiotic approach restores intestinal homeostasis and prolongs survival in leukaemic mice with cachexia

(2015) Laure B Bindels et al.   ISME Journal

Clinical Evidence of Effects of Lactobacillus plantarum HY7714 on Skin Aging: A Randomized, Double Blind, Placebo-Controlled Study

(2015) Dong Eun Lee et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Library preparation methodology can influence genomic and functional predictions in human microbiome research

(2015) Marcus B. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Dynamics of the Gut Microbiome in Elderly People during Probiotic Consumption

(2015) Emiley A. Eloe-Fadrosh et al.   mBio

Obesity and the microbiome

(2015) Ruchi Mathur et al.   Expert Review of Gastroenterology & Hepatology

Effects of Surgical and Dietary Weight Loss Therapy for Obesity on Gut Microbiota Composition and Nutrient Absorption

(2015) Antje Damms-Machado et al.   Biomed Research International

Aging and the human gut microbiota—from correlation to causality

(2015) Sitaraman Saraswati et al.   Frontiers in Microbiology

Biomarkers for physical frailty and sarcopenia: state of the science and future developments

(2015) Riccardo Calvani et al.   Journal of Cachexia Sarcopenia and Muscle

Combining metagenomics, metatranscriptomics and viromics to explore novel microbial interactions: towards a systems-level understanding of human microbiome

(2015) Shirley Bikel et al.   Computational and Structural Biotechnology Journal

Review on microbiota and effectiveness of probiotics use in older

(2015) Mariangela Rondanelli   World Journal of Clinical Cases

Commentary: synbiotics and gut microbiota in older people - a microbial guide to healthy ageing

(2015) E. M. M. Quigley   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Effect of Oral Administration of Lactobacillus plantarum HY7714 on Epidermal Hydration in Ultraviolet B-Irradiated Hairless Mice

(2015) Jehyeon Ra et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Effects of dietary polyphenol-rich plant products from grape or hop on pro-inflammatory gene expression in the intestine, nutrient digestibility and faecal microbiota of weaned pigs

(2014) Anja Fiesel et al.   BMC Veterinary Research

You Are What You Host: Microbiome Modulation of the Aging Process

(2014) Caroline Heintz et al.   CELL

The cross talk between microbiota and the immune system: metabolites take center stage

(2014) Hagit Shapiro et al.   CURRENT OPINION IN IMMUNOLOGY

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice

(2014) Fernando F Anhê et al.   GUT

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Gut microbiota–generated metabolites in animal health and disease

(2014) Won-Jae Lee et al.   Nature Chemical Biology

The Impact of Different DNA Extraction Kits and Laboratories upon the Assessment of Human Gut Microbiota Composition by 16S rRNA Gene Sequencing

(2014) Nicholas A. Kennedy et al.   PLoS One

Host lifestyle affects human microbiota on daily timescales

(2014) Lawrence A David et al.   GENOME BIOLOGY

Kraken: ultrafast metagenomic sequence classification using exact alignments

(2014) Derrick E Wood et al.   GENOME BIOLOGY

Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double-blind, placebo-controlled crossover study

(2013) S. Macfarlane et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases

(2013) Thea Magrone et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

(2013) Filipe Cabreiro et al.   CELL

The role of gut microbiota in nutritional status

(2013) Eibhlís M. O’Connor   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Implications of the human microbiome in inflammatory bowel diseases

(2013) Syeda M. Bakhtiar et al.   FEMS MICROBIOLOGY LETTERS

Muscle wasting: The gut microbiota as a new therapeutic target?

(2013) Laure B. Bindels et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

(2013) Marco Candela et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Computational meta'omics for microbial community studies

(2013) N. Segata et al.   Molecular Systems Biology

Computing: A vision for data science

(2013) Chris A. Mattmann   NATURE

The big challenges of big data

(2013) Vivien Marx   NATURE

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Metagenomic species profiling using universal phylogenetic marker genes

(2013) Shinichi Sunagawa et al.   NATURE METHODS

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Re-print of “Intestinal luminal nitrogen metabolism: Role of the gut microbiota and consequences for the host”

(2013) Anne-Marie Davila et al.   PHARMACOLOGICAL RESEARCH

The Enterocyte-Associated Intestinal Microbiota of Breast-Fed Infants and Adults Responds Differently to a TNF-α-Mediated Pro-Inflammatory Stimulus

(2013) Manuela Centanni et al.   PLoS One

Structural modulation of gut microbiota in life-long calorie-restricted mice

(2013) Chenhong Zhang et al.   Nature Communications

How much metagenomic sequencing is enough to achieve a given goal?

(2013) Jiajia Ni et al.   Scientific Reports

Lipopolysaccharide Causes an Increase in Intestinal Tight Junction Permeability in Vitro and in Vivo by Inducing Enterocyte Membrane Expression and Localization of TLR-4 and CD14

(2012) Shuhong Guo et al.   AMERICAN JOURNAL OF PATHOLOGY

Modulation of the gut microbiota with antibiotic treatment suppresses whole body urea production in neonatal pigs

(2012) Patrycja Puiman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Coverage evaluation of universal bacterial primers using the metagenomic datasets

(2012) Dan-Ping Mao et al.   BMC MICROBIOLOGY

Bacteria as vitamin suppliers to their host: a gut microbiota perspective

(2012) Jean Guy LeBlanc et al.   CURRENT OPINION IN BIOTECHNOLOGY

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach

(2012) Ana Elena Pérez-Cobas et al.   GUT

The gut microbiota regulates bone mass in mice

(2012) Klara Sjögren et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

A framework for human microbiome research

(2012)   NATURE

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

Metagenomic microbial community profiling using unique clade-specific marker genes

(2012) Nicola Segata et al.   NATURE METHODS

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Categorization of the gut microbiota: enterotypes or gradients?

(2012) Ian B. Jeffery et al.   NATURE REVIEWS MICROBIOLOGY

The interplay between the intestinal microbiota and the brain

(2012) Stephen M. Collins et al.   NATURE REVIEWS MICROBIOLOGY

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Defining the human microbiome

(2012) Luke K Ursell et al.   NUTRITION REVIEWS

Ageing and gut microbes: Perspectives for health maintenance and longevity

(2012) Elena Biagi et al.   PHARMACOLOGICAL RESEARCH

Restoring Specific Lactobacilli Levels Decreases Inflammation and Muscle Atrophy Markers in an Acute Leukemia Mouse Model

(2012) Laure B. Bindels et al.   PLoS One

A Core Human Microbiome as Viewed through 16S rRNA Sequence Clusters

(2012) Susan M. Huse et al.   PLoS One

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

A randomised crossover study investigating the effects of galacto-oligosaccharides on the faecal microbiota in men and women over 50 years of age

(2011) Gemma E. Walton et al.   BRITISH JOURNAL OF NUTRITION

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Integrative analysis of environmental sequences using MEGAN4

(2011) D. H. Huson et al.   GENOME RESEARCH

Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics

(2011) T A Ajslev et al.   INTERNATIONAL JOURNAL OF OBESITY

A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l-tuples

(2011) Yu-Wei Wu et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Gut feelings: the emerging biology of gut–brain communication

(2011) Emeran A. Mayer   NATURE REVIEWS NEUROSCIENCE

The microbiome-gut-brain axis: from bowel to behavior

(2011) J. F. Cryan et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Diet Drives Convergence in Gut Microbiome Functions Across Mammalian Phylogeny and Within Humans

(2011) B. D. Muegge et al.   SCIENCE

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Contributions of Intestinal Bacteria to Nutrition and Metabolism in the Critically Ill

(2011) Michael J. Morowitz et al.   SURGICAL CLINICS OF NORTH AMERICA

Introducing W.A.T.E.R.S.: a Workflow for the Alignment, Taxonomy, and Ecology of Ribosomal Sequences

(2010) Amber L Hartman et al.   BMC BIOINFORMATICS

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

(2010) Elena Biagi et al.   PLoS One

Composition, variability, and temporal stability of the intestinal microbiota of the elderly

(2010) M. J. Claesson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities

(2009) P. D. Schloss et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age

(2009) D Mariat et al.   BMC MICROBIOLOGY

The effect of age and non-steroidal anti-inflammatory drugs on human intestinal microbiota composition

(2009) Harri Mäkivuokko et al.   BRITISH JOURNAL OF NUTRITION

The inflammatory status of old age can be nurtured from the intestinal environment

(2009) Yves Guigoz et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Better living through microbial action: the benefits of the mammalian gastrointestinal microbiota on the host

(2009) Thomas D. Leser et al.   ENVIRONMENTAL MICROBIOLOGY

Towards the human intestinal microbiota phylogenetic core

(2009) Julien Tap et al.   ENVIRONMENTAL MICROBIOLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Gut microbiota: Changes throughout the lifespan from infancy to elderly

(2009) Paul W. O'Toole et al.   INTERNATIONAL DAIRY JOURNAL

Intestinal Nitrogen Recycling and Utilization in Health and Disease

(2009) Werner G. Bergen et al.   JOURNAL OF NUTRITION

Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers

(2009) Luying Peng et al.   JOURNAL OF NUTRITION

The inflammatory status of the elderly: The intestinal contribution

(2009) Eduardo J. Schiffrin et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Interactions of gut microbiota with functional food components and nutraceuticals

(2009) J.M. Laparra et al.   PHARMACOLOGICAL RESEARCH

Short-chain fatty acids act as antiinflammatory mediatorsby regulating prostaglandin E2 and cytokines

(2009) Mary Ann Cox et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Effects of Maturation on the Colonic Microflora in Infancy and Childhood

(2009) P. Enck et al.   Gastroenterology Research and Practice

Metagenetics: spending our inheritance on the future

(2009) Jo Handelsman   Microbial Biotechnology

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

Substantial biases in ultra-short read data sets from high-throughput DNA sequencing

(2008) J. C. Dohm et al.   NUCLEIC ACIDS RESEARCH

A Molecular Study of Microbe Transfer between Distant Environments

(2008) Sean D. Hooper et al.   PLoS One

The role of microbiota in infectious disease

(2008) Bärbel Stecher et al.   TRENDS IN MICROBIOLOGY

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

(2007) Antero Salminen et al.   AGEING RESEARCH REVIEWS