Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors

Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure

(2016) Dale J. Hamilton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial Metabolism in Aging Heart

(2016) Edward J. Lesnefsky et al.   CIRCULATION RESEARCH

Compartment-specific Control of Reactive Oxygen Species Scavenging by Antioxidant Pathway Enzymes

(2016) Swati Dey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial function as a therapeutic target in heart failure

(2016) David A. Brown et al.   Nature Reviews Cardiology

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

TNF-  down-regulates sarcoplasmic reticulum Ca2+ ATPase expression and leads to left ventricular diastolic dysfunction through binding of NF- B to promoter response element

(2015) C.-T. Tsai et al.   CARDIOVASCULAR RESEARCH

Mesenchymal stem cell-derived inflammatory fibroblasts promote monocyte transition into myeloid fibroblasts via an IL-6-dependent mechanism in the aging mouse heart

(2015) Katarzyna A. Cieslik et al.   FASEB JOURNAL

Age-associated pro-inflammatory remodeling and functional phenotype in the heart and large arteries

(2015) Mingyi Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Heart failure with preserved ejection fraction in the elderly: scope of the problem

(2015) Bharathi Upadhya et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Left Atrial Volume and Pulmonary Artery Diameter Are Noninvasive Measures of Age-Related Diastolic Dysfunction in Mice

(2015) Guillermo Medrano et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function

(2014) Andrea M. Cordero-Reyes et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Recovery of Indicators of Mitochondrial Biogenesis, Oxidative Stress, and Aging With (−)-Epicatechin in Senile Mice

(2014) Aldo Moreno-Ulloa et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Glutathione: new roles in redox signaling for an old antioxidant

(2014) Katia Aquilano et al.   Frontiers in Pharmacology

Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione

(2013) Dan Nguyen et al.   AGING CELL

Oxidative stress in cardiomyocytes contributes to decreased SERCA2a activity in rats with metabolic syndrome

(2013) Jaime Balderas-Villalobos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Left atrial volumes and associated stroke subtypes

(2013) Quratulain Shaikh et al.   BMC Neurology

Causes and Consequences of CysteineS-Glutathionylation

(2013) Christina L. Grek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts

(2013) Katarzyna A. Cieslik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Hydrogen Peroxide–Mediated SERCA Cysteine 674 Oxidation Contributes to Impaired Cardiac Myocyte Relaxation in Senescent Mouse Heart

(2013) Fuzhong Qin et al.   Journal of the American Heart Association

Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease

(2012) Dao-Fu Dai et al.   ANTIOXIDANTS & REDOX SIGNALING

Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age

(2012) Gautam Sikka et al.   EXPERIMENTAL GERONTOLOGY

Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

(2011) R. V. Sekhar et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

S-Glutathionylation: From Molecular Mechanisms to Health Outcomes

(2011) Ying Xiong et al.   ANTIOXIDANTS & REDOX SIGNALING

The ageing lens and cataract: a model of normal and pathological ageing

(2011) R. Michael et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Aging impairs myocardial fatty acid and ketone oxidation and modifies cardiac functional and metabolic responses to insulin in mice

(2010) Outi M. Hyyti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart

(2010) Katarzyna A. Cieslik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Is the oxidative stress theory of aging dead?

(2009) Viviana I. Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging

(2009) Dao-Fu Dai et al.   CIRCULATION

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Antioxidants prevent health-promoting effects of physical exercise in humans

(2009) M. Ristow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA