Compartment-specific Control of Reactive Oxygen Species Scavenging by Antioxidant Pathway Enzymes

Mechanisms of Sudden Cardiac Death: Oxidants and Metabolism

(2015) K.-C. Yang et al.   CIRCULATION RESEARCH

Inhibiting Mitochondrial Na + /Ca 2+ Exchange Prevents Sudden Death in a Guinea Pig Model of Heart Failure

(2014) Ting Liu et al.   CIRCULATION RESEARCH

The Mitochondrial Thioredoxin is Required for Liver Development in Zebrafish

(2014) J. Zhang et al.   CURRENT MOLECULAR MEDICINE

Identification of Novel Nuclear Targets of Human Thioredoxin 1

(2014) Changgong Wu et al.   MOLECULAR & CELLULAR PROTEOMICS

Monoamine Oxidase B Prompts Mitochondrial and Cardiac Dysfunction in Pressure Overloaded Hearts

(2013) Nina Kaludercic et al.   ANTIOXIDANTS & REDOX SIGNALING

The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells

(2013) Christine C. Winterbourn   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

(2013) Hazel H Szeto   BRITISH JOURNAL OF PHARMACOLOGY

A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities

(2013) Juliana A. Ronchi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hyperoxidation of Peroxiredoxins 2 and 3

(2013) Alexander V. Peskin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of Early Reperfusion Injury With the Mitochondria-Targeting Peptide Bendavia

(2013) David A. Brown et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin

(2013) A. V. Birk et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Thioredoxin and Thioredoxin Target Proteins: From Molecular Mechanisms to Functional Significance

(2012) Samuel Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

The contribution of thioredoxin-2 reductase and glutathione peroxidase to H2O2 detoxification of rat brain mitochondria

(2012) Alexei P. Kudin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Redox Signaling in Cardiac Physiology and Pathology

(2012) Joseph R. Burgoyne et al.   CIRCULATION RESEARCH

Glutathione/thioredoxin systems modulate mitochondrial H2O2emission: An experimental-computational study

(2012) Miguel Antonio Aon et al.   JOURNAL OF GENERAL PHYSIOLOGY

Nitric oxide synthase uncoupling: A therapeutic target in cardiovascular diseases

(2012) Nathan D. Roe et al.   VASCULAR PHARMACOLOGY

Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure

(2011) Dao-Fu Dai et al.   CIRCULATION RESEARCH

Measuring EGSH and H2O2 with roGFP2-based redox probes

(2011) Bruce Morgan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox signaling in cardiac myocytes

(2011) Celio X.C. Santos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Distinction of thioredoxin transnitrosylation and denitrosylation target proteins by the ICAT quantitative approach

(2011) Changgong Wu et al.   Journal of Proteomics

Fluorescent Protein-Based Redox Probes

(2010) Andreas J. Meyer et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox-optimized ROS balance: A unifying hypothesis

(2010) M.A. Aon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Regulation of Mitochondrial Glutathione Redox Status and Protein Glutathionylation by Respiratory Substrates

(2010) Jerome Garcia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic modifier of mitochondrial superoxide dismutase-deficient mice delays heart failure and prolongs survival

(2010) Aekyong Kim et al.   MAMMALIAN GENOME

Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

(2009) Andrew G. Cox et al.   BIOCHEMICAL JOURNAL

Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging

(2009) Dao-Fu Dai et al.   CIRCULATION

Monoamine Oxidase A–Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload

(2009) Nina Kaludercic et al.   CIRCULATION RESEARCH

Cardiac-Specific Overexpression of Catalase Identifies Hydrogen Peroxide-Dependent and -Independent Phases of Myocardial Remodeling and Prevents the Progression to Overt Heart Failure in Gαq-Overexpressing Transgenic Mice

(2009) Fuzhong Qin et al.   Circulation-Heart Failure

Reversible oxidation of mitochondrial peroxiredoxin 3 in mouse heart subjected to ischemia and reperfusion

(2009) Vikas Kumar et al.   FEBS LETTERS

Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases

(2009) Marcus Gutscher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

(2009) Marcin Kortylewski et al.   NATURE BIOTECHNOLOGY

Cytoprotective Nrf2 Pathway Is Induced In Chronically Txnrd 1-Deficient Hepatocytes

(2009) Elena S. Suvorova et al.   PLoS One

Why Have Antioxidants Failed in Clinical Trials?

(2008) Steven R. Steinhubl   AMERICAN JOURNAL OF CARDIOLOGY

Redox Signaling, Vascular Function, and Hypertension

(2008) Moo Yeol Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

(2008) Andrew G. Cox et al.   BIOCHEMICAL PHARMACOLOGY

An attempt to prevent senescence: A mitochondrial approach

(2008) Vladimir P. Skulachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates

(2008) Kristin K. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE