Article
Environmental Sciences
Yi-Lin Huang, Wen-Lin Pan, Wen-Wu Cai, Jia-Qian Ju, Shao-Chen Sun
Summary: This study indicates that citrinin has adverse effects on early embryo development through inducing DNA damage, autophagy, and disrupting mitochondria function.
ENVIRONMENTAL TOXICOLOGY
(2021)
Article
Environmental Sciences
Yonggang Ma, Chenguang Yue, Qiannan Sun, Yangyang Wang, Zhonggui Gong, Kanglei Zhang, Jiansen Da, Hui Zou, Jiaqiao Zhu, Hongyan Zhao, Ruilong Song, Zongping Liu
Summary: This study investigated the effects of cadmium on diabetic kidney injury and its underlying mechanism. The results showed that cadmium exposure exacerbated diabetic kidney injury, potentially through inhibition of autophagy.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Biochemistry & Molecular Biology
Xudong Shen, Zequn Tang, Yu Bai, Meishuo Wan, Miao Yu, Jingyi Chen, Guangxing Li, Ruili Zhang, Ming Ge
Summary: The study suggests that APS can alleviate Cd-induced CEF autophagy damage by reducing the production of ROS, thereby restoring the viability and morphological damage of CEF exposed to Cd.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Liang-Jun Yan, Daniel C. Allen
Summary: Cadmium, a nonessential metal heavily polluting the environment, can cause chronic damage to the kidneys, mainly accumulating in and damaging the proximal tubule of nephrons. Oxidative damage serves as a unifying mechanism for cadmium-induced renal toxicity, with antioxidants potentially ameliorating the injury.
Article
Immunology
Tingting Xie, Min Feng, Xi Zhang, Xiaoqi Li, Guodong Mo, Meiqing Shi, Xiquan Zhang
Summary: Autophagy plays a crucial role in host antiviral defense, but the mechanisms underlying autophagy inhibition by ALV-J are unknown. In this study, the researchers found that CH25H induces autophagy and inhibits ALV-J infection, providing a new understanding of how CH25H inhibits viral replication.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Food Science & Technology
Xiaoqing Ying, Yuxiang Pan, Jinchi Lan, Yumeng Fang, Yin-Yi Ding, Zhenyu Gu
Summary: In this study, it was found that the pH-temperature modified fingered citron peel pectin (mFCPP) showed higher cadmium removal ability compared to unmodified fingered citron peel pectin (FCPP). A 20-week study in cadmium-exposed mice suggested significant improvement in liver and kidney function with co-treatment of pectin. The study also demonstrated that both FCPP and mFCPP were impermeable through the intestinal wall, suggesting their binding with the cadmium ions in the gastrointestinal tract, thus preventing cadmium ions absorption and entry into the systemic circulation.
Article
Environmental Sciences
Xishuai Tong, Xiaohui Fu, Gengsheng Yu, Huayi Qu, Hui Zou, Ruilong Song, Yonggang Ma, Yan Yuan, Jianchun Bian, Jianhong Gu, Zongping Liu
Summary: Cadmium (Cd) is a harmful environmental heavy metal that accumulates in the body and causes various health problems. Polystyrene (PS), a type of microplastic, also has toxic effects. The study aimed to investigate the effects of PS on Cd-induced mitochondrial damage in the lungs of mice.
ENVIRONMENTAL TOXICOLOGY
(2023)
Article
Cell Biology
Sandra Franco-Iborra, Ainhoa Plaza-Zabala, Marta Montpeyo, David Sebastian, Miquel Vila, Marta Martinez-Vicente
Summary: The study found that HTT protein plays a crucial role in mitophagy, and the expansion of its polyQ tract affects this process, ultimately leading to the accumulation of damaged mitochondria and an increase in oxidative stress, leading to negative effects on mitochondrial dysfunction and neurodegeneration in Huntington disease.
Article
Biochemistry & Molecular Biology
Hui Zou, Yan Chen, Huayi Qu, Jian Sun, Tao Wang, Yonggang Ma, Yan Yuan, Jianchun Bian, Zongping Liu
Summary: Cadmium is a potential pathogenic factor in kidney diseases, and microplastics are major carriers of contaminants. In vivo experiments showed that microplastics aggravated cadmium-induced kidney injury, potentially through oxidative stress, autophagy, apoptosis, and fibrosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Waseem Ali, Kai Deng, Jian Sun, Yonggang Ma, Zongping Liu, Hui Zou
Summary: Autophagy plays a critical role in spermatogenesis, but disruption of autophagic flux can lead to cell death. This study reveals that cadmium-induced autophagy might be involved in the regulation of spermiophagy and highlights the potential high risk to male fertility in the context of cadmium toxicity.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Lulu Wei, Ranran Wang, Kai Lin, Xiaolu Jin, Li Li, Junaid Wazir, Wenyuan Pu, Panpan Lian, Renwei Lu, Shiyu Song, Quan Zhao, Jiabin Li, Hongwei Wang
Summary: This study investigated the impact of creatine supplementation on weight loss and muscle wasting in cancer cachexia, and found that creatine supplementation protected against body weight and muscle loss, improved grip strength, and mitigated mitochondrial dysfunction in cachectic muscle.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Environmental Sciences
Jiaqiao Zhu, Zhutao Huang, Fan Yang, Min Zhu, Jiangqin Cao, Jiali Chen, Yan Lin, Shuai Guo, Junwei Li, Zongping Liu
Summary: This study demonstrated that maternal cadmium exposure impairs preimplantation embryo development by disturbing epigenetic modification and inducing DNA damage. The exposure to cadmium led to embryo death, fragmentation, and developmental blockade, while affecting histone acetylation and disrupting DNA methylation of H19. Additionally, cadmium increased reactive oxygen species levels and DNA damage, while partly inhibiting gene expression related to DNA repair. Mitochondrial distribution and activity were also increased, contributing to intracellular homeostasis for embryo survival.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Engineering, Environmental
Zhong-Gui Gong, Yuan Zhao, Zhen-Yong Wang, Rui-Feng Fan, Zong-Ping Liu, Lin Wang
Summary: The study demonstrates that BRD4 acts as a transcriptional repressor in mediating lysosomal dysfunction, autophagy blockade, and oxidative stress during Cd exposure, showing its potential as a therapeutic target for Cd-induced AKI.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Cell Biology
Meng-Hao Pan, Cheng-Cheng Zhu, Jia-Qian Ju, Yi Xu, Shi-Ming Luo, Shao-Chen Sun, Xiang-Hong Ou
Summary: The study suggests that obesity affects early embryonic development in mice by inducing DNA damage, aberrant histone methylation, and changes in autophagy levels.
JOURNAL OF CELLULAR PHYSIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Fang Yuan, Yingying Xu, Kai You, Jiaye Zhang, Fan Yang, Yin-xiong Li
Summary: The study showed that calcitriol can alleviate ethanol-induced hepatocyte damage by enhancing autophagy, providing a convenient preventive and hepatoprotective means for people who occasionally engage in social drinking. Autophagy is significantly enhanced by calcitriol, and the effect is mediated through the AMPK/mTOR signaling pathway and dependent on the Vitamin D receptor (VDR).
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2021)
Article
Physics, Mathematical
Diederik van Engelenburg, Marcin Lis
Summary: In this study, a power-law lower bound on the two-point function of the planar XY spin model at low temperatures is obtained using elementary methods. This result, initially rigorously derived by Frohlich and Spencer (1981), establishes a Berezinskii-Kosterlitz-Thouless phase transition in the model. The argument relies on a new loop representation of spin correlations, recent research on delocalisation of general integer-valued height functions, and classical correlation inequalities.
COMMUNICATIONS IN MATHEMATICAL PHYSICS
(2023)
Review
Biochemistry & Molecular Biology
Wojciech Trybus, Ewa Trybus, Teodora Krol
Summary: Lysosomes are organelles that contain acidic hydrolases and play a crucial role in cellular degradation and homeostasis. They are involved in autophagy and various cell death pathways, including lysosomal and apoptotic death. Compounds such as lysosomotropic compounds, antihistamines, DNA-damaging drugs, and chemotherapeutics can induce lysosomal membrane permeability, promoting lysosomal-mediated cell death. Combining lysosomotropic compounds with autophagy modulators may be a promising approach in cancer treatment and overcoming chemoresistance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Infectious Diseases
Michal Milek, Ewa Ciszkowicz, Ewelina Sidor, Joanna Heclik, Katarzyna Lecka-Szlachta, Malgorzata Dzugan
Summary: The aim of this study was to assess the impact of selected fruits and herbs, categorized as superfoods, on the bioactivity of rapeseed honey. Flavored creamed honeys with different additives were prepared and analyzed for their phenols, flavonoids, antioxidant, and antibacterial properties. The study also examined the antioxidant properties after three months of storage. Results showed a significant dose-dependent increase in bioactive ingredients and antioxidant capacity in spiced honeys compared to the control. The addition of sea buckthorn leaves and black raspberry fruits had the highest enrichment.
Article
Agronomy
Monika Tomczyk, Grzegorz Zagula, Mateusz Kaczmarski, Czeslaw Puchalski, Malgorzata Dzugan
Summary: This study aimed to assess the levels of harmful metals and essential macro- and microelements in three melliferous plant species and their transferability to honey. The study found that although harmful metals accumulate in plants, they are only present in trace amounts in honey and do not affect its beneficial mineral composition.
Article
Food Science & Technology
Malgorzata Dzugan, Michal Milek, Ewelina Sidor, Justyna Buczkowicz, Joanna Heclik, Aleksandra Bocian
Summary: The study aimed to use proteins and amino acids as indicators to confirm the variety of honey stated on the label. The results showed that differences in protein SDS-PAGE profiles and amino acid HPTLC analysis can be used to detect variations among different honey varieties. These tools can be used for the initial verification of honey variety.
FOOD ANALYTICAL METHODS
(2023)
Article
Biochemistry & Molecular Biology
Monika Tomczyk, Anna Czerniecka-Kubicka, Michal Milek, Ewelina Sidor, Malgorzata Dzugan
Summary: The study evaluated the changes in thermal characteristics, physicochemical parameters, antioxidant, and enzymatic activity of honey subjected to artificial adulteration. Differential scanning calorimetry (DSC) was used to detect honey adulteration, and specific glass transitions (TG) were observed in adulterated honeys in the range of 34-38.05 degrees C, with additional T(g)s observed for honeys adulterated by syrup only (-19.5 degrees C to 4.10 degrees C) and honeys adulterated by invert (50.4-57.6 degrees C). These specific TG can be useful for detecting honey adulteration and identifying the adulterant used.
Article
Statistics & Probability
Nathanael Berestycki, Marcin Lis, Wei Qian
Summary: We study the dimer model on subgraphs of the square lattice with unmatched vertices on a prescribed part of the boundary, called monomers, contributing to the total weight of the configuration. A bijection relates this model to a standard dimer model on a non-bipartite graph. The Kasteleyn matrix describes a walk with negative transition weights along the free boundary, but under certain assumptions, an effective random walk representation for the inverse Kasteleyn matrix is proved in the infinite volume limit.
PROBABILITY THEORY AND RELATED FIELDS
(2023)
Article
Chemistry, Physical
Krzysztof Gondek, Piotr Micek, Agnieszka Baran, Tomasz Bajda, Jerzy Kowal, Marcin Lis, Anna Wyrobisz-Papiewska, Dorota Wojtysiak, Krzysztof Smoron
Summary: Diatomite has been extensively studied for its potential use in industry, breeding, and agriculture. The research focuses on reducing the mobility of heavy metals in the environment by using diatomite and modifying its properties. The study aims to develop a cost-effective material with improved chemical and physical properties for metal immobilization compared to regular diatomite.
Article
Chemistry, Multidisciplinary
Malgorzata Dzugan, Ewelina Sidor, Michal Milek, Monika Tomczyk
Summary: The researchers aimed to design an innovative dietary supplement containing freeze-dried drone brood enriched with calcium ions. They found that the components of drone brood were more bioaccessible from the supplements enriched with ground chicken eggshell compared to those enriched with calcium carbonate. This newly proposed two-ingredient supplement shows potential for treating osteoporosis but further studies are needed.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Michal Milek, Mateusz Molon, Monika Kula-Maximenko, Ewelina Sidor, Grzegorz Zagula, Malgorzata Dzugan
Summary: The aim of this research was to determine the impact of selected factors (temperature, ultrasound) and Lactobacillus rhamnosus inoculum on the quality of the bee bread substitute produced from converted pollen. The composition of the fermented pollen was analyzed using various methods, and its biological activity was assessed. The results showed that fermentation of pollen led to changes in composition, higher polyphenol content, comparable antioxidant activity to bee bread, and accelerated yeast growth rate.
Article
Infectious Diseases
Andrzej Lyskowski, Michal Milek, Malgorzata Dzugan
Summary: The availability of reference proteomes for two honeybee species allows for in silico study of protein fractions related to honey's antimicrobial activity. Using a database of established antimicrobial peptides, protein components with similar sequences were identified and analyzed. The results show conserved localization of antimicrobial peptide sequences in a limited number of protein components. The composition of the antibacterial peptides identified in the proteomes of both species is also found to be similar.
Article
Biochemistry & Molecular Biology
Michal Milek, Mateusz Molon, Patrycja Kielar, Ewelina Sidor, Aleksandra Bocian, Katarzyna Marciniak-Lukasiak, Anna Pasternakiewicz, Malgorzata Dzugan
Summary: The study aimed to compare the nutritional value and bioactivity of honey enriched with natural bee bread and substitutes obtained through laboratory fermentation of bee pollen. Physicochemical parameters, antioxidant properties, and bioaccessibility of proteins were analyzed. The enriched honeys showed similarity to natural honey, with good bioaccessibility of proteins and greater protection against oxidative stress and yeast growth compared to pure rapeseed honey. The samples also exhibited significant genoprotective activity against DNA double-strand breaks.
Article
Entomology
Monika Tomczyk, Julita Kusibab, Alicja Zachara, Malgorzata Dzugan
Summary: This study analyzed the mercury content in local and imported honeys and found that the concentration of mercury in all tested samples did not exceed the applicable legal limit. Additionally, no significant differences were found in mercury contamination based on honey variety or country of origin. The study concluded that the Direct Mercury Analyzer (DMA) is an excellent tool for screening mercury in honeys due to its simplicity, rapidity, low detection limit, accuracy, precision, and no sample preparation.
JOURNAL OF APICULTURAL SCIENCE
(2023)
Article
Cell Biology
Ewa Trybus, Wojciech Trybus, Teodora Krol
Summary: This study focused on the cytological analysis of nasal mucosa swabs from patients with allergic rhinitis (AR) and nonallergic/vasomotor rhinitis (NAR/VMR) who received azelastine therapy for 4 weeks. The results demonstrated therapeutic benefits of azelastine, including regeneration of ciliated cells and induction of autophagy and apoptosis in epithelial cells. The study provides new insights into the mechanisms of action of azelastine and contributes to the understanding of prognostic indicators in different types of rhinitis.
Article
Biochemistry & Molecular Biology
Sadia Anjum, Hamile Ali, Faiza Naseer, Maisa S. Abduh, Halima Qadir, Salik Kakar, Yasir Waheed, Tahir Ahmad
Summary: This study demonstrates that avocado and papaya fruit juices can reduce the accumulation of cadmium in the liver, kidney, and hippocampal tissues, and upregulate the expression of antioxidant enzymes while reducing lipid peroxidation. Compared to avocado, papaya has a stronger potential for improving memory and learning, as well as reducing lipid peroxidation in various tissues.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Celio Junior da C. Fernandes, Gerson Santos de Almeida, Patricia Fretes Wood, Anderson M. Gomes, Fabio J. Bezerra, Jose C. S. Vieira, Pedro M. Padilha, Willian F. Zambuzzi
Summary: This study demonstrates the role of mechanosignaling in the promotion of an osteoblastic phenotype in response to zirconia exposure. The release of angiocrine factors modulated by mechanosignaling is crucial in creating a microenvironment that promotes wound healing and osseointegration. These findings highlight the importance of considering endothelial cell mechanosignaling in bone healing and osseointegration in the context of blood vessel effects.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Rehab I. Abdel-Karim, Rania K. Hashish, Dahlia I. Badran, Sally S. Mohammed, Noha A. Salem
Summary: The study found that chlorpyrifos has hepatotoxicity, while cerium oxide nanoparticles can alleviate this toxicity. Cerium oxide nanoparticles can protect the liver by reducing the expression of inflammatory and apoptotic proteins and increasing the activity of antioxidant enzymes.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Tahani El Ayari, Raja Ben Ahmed, Zaineb Hammemi, Abdessalem Kouki, Emna Chelb, Salwa Nechi, Najoua Trigui El Menif
Summary: This study assessed the effects of samarium doped zinc oxide nanoparticles (Sm doped ZnO NPs) on the edible mussel Mytilus galloprovincialis and found that it led to a decrease in filtration rates and histopathological alterations in the gills, digestive glands, and gonads.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shanshan Niu, Zhangmin Wang, Xuebin Yin, Xiaodong Liu, Liqiang Qin, Muhammad Raza Farooq, Ofori Prince Danso, Zezhou Zhang, Qin Luo, Chenlu Sun, Jiaping Song
Summary: This study investigated the transport of selenium through the soil-crop-human chain in regions with different selenium levels. It found that the residents' dietary selenium intake was related to the selenium content in soil, with one village within the WHO recommended intake range while the other village was at risk of selenium deficiency. There were significant positive correlations between residents' dietary selenium intake and the three selenium biomarkers.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Sanaz Salaramoli, Hamid Reza Joshaghani, Ali Shoeibi, Seyed Isaac Hashemy
Summary: The study suggests that serum levels of selenium and selenoprotein P may serve as biomarkers or risk factors for Parkinson's disease. Additionally, there is a correlation between alpha-synuclein levels and disease stage. Further research is needed to understand the role of selenoprotein S in reducing alpha-synuclein aggregation.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Motozumi Ando, Keiko Suzuki, Riko Kitamoto, Ayako Nakayama, Norio Watanabe, Masami Kawahara
Summary: C57BL/6 mice and BALB/c mice showed different expression profiles of selenoprotein P after a high-fat diet (HFD). C57BL/6 mice in the HFD group had higher body weight, fasting plasma glucose levels, and plasma selenoprotein P levels compared to the ND group. However, BALB/c mice did not show significant differences in fasting plasma selenoprotein P levels between the HFD and ND groups.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ruihan Song, Huanhuan Chen, Runqing Zhan, Miaomiao Han, Longzhu Zhao, Xiaoli Shen
Summary: This study aims to investigate the protective effects of Vitamin E (Vit E) on manganese (Mn)-induced nigrostriatal system lesions. The results demonstrate that Vit E improves behavioral disorders, attenuates the loss of nigral dopaminergic neurons, and restores mitochondrial function. Additionally, the protective effect of Vit E may be associated with the upregulation of CHRM1 and KCNJ4 mRNA.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jose Luan da Paixao Teixeira, Ana Paula Rebellato, Maria Isabel Andrekowisk Fioravanti, Raquel Fernanda Milani, Marcelo Antonio Morgano
Summary: The study aimed to determine the total Se content and bioaccessibility in commercial plant-based beverages, with results showing that only one beverage made from organic cashew nuts could meet the recommended Se intake for different populations. High bioacessibility percentages were observed in the beverages.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Andreas F. Lehner, Sarah Rebolloso, Paul P. Calle, Karen Ingerman, Gregory A. Lewbart, Juan Pablo Munoz-Perez, Carlos A. Valle, John P. Buchweitz
Summary: The dried blood spot (DBS) technology is useful for storing blood samples from wildlife, and this study developed methods for measuring several important elements in DBS and used them for health assessments of Galapagos land iguanas. The results showed that the DBS samples accurately reflected the concentrations of various elements compared to plasma samples, with some divergences observed between different species.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Zhou, Chunbei Zhou, Jun Xie, Fei Luo, Ning Yao
Summary: The study illustrates the changes in iodized salt usage, goiter rate, and median urinary iodine concentration in school-aged children in Chongqing over the past 21 years. Adequate iodized salt consumption can eliminate iodine deficiency disorders in children, but excessive iodine intake from salt can lead to high urinary iodine excretion and even goiter. Continuous monitoring and adjustment of iodine fortification levels in household table salt is crucial.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Agustin B. Actis Dato, Valeria R. Martinez, Jorge O. Velez Rueda, Enrique L. Portiansky, Veronica De Giustu, Evelina G. Ferrer, Patricia A. M. Williams
Summary: The zinc coordination complex ZnMD, synthesized in this study, showed promising effects in treating hypertension and cardiac hypertrophy. It was more effective than the antihypertensive drug MD in reducing blood pressure and preventing myocardial hypertrophy. ZnMD also exhibited protective effects on the heart by reducing oxidative damage and regulating the expression of oxidative enzymes. These findings suggest that ZnMD has the potential to be developed as a therapeutic drug for hypertension and cardiac dysfunction.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mina Sarani, Maryam Roostaee, Mahboubeh Adeli-Sardou, Davood Kalantar-Neyestanaki, Seyed Amin Ayatollahi Mousavi, Azam Amanizadeh, Mahmood Barani, Alireza Amirbeigi
Summary: This study successfully synthesized nano bismuth oxide using green synthesis methods. The nano particles doped with silver and copper demonstrated excellent antibacterial properties and selective cytotoxicity against cancer cells. These findings have important implications for biomedical and therapeutic applications.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mona Abdel-Rahman, Heba M. Elmasry, Omar A. Ahmed-Farid, Sherein M. Hegazy, Mohamed M. Rezk
Summary: This study investigates the neuro effects of lanthanides on different brain areas in rats and finds that they can distribute and accumulate in various brain regions. Treatment with cerium nanoparticles or lanthanum causes a significant decrease in norepinephrine, dopamine, serotonin, and GABA, accompanied by a significant increase in 5-hydroxyl indoleacetic acid levels. Moreover, cerium nanoparticles exhibit high activity in scavenging free radicals.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mahshid Deldar Abad Paskeh, Nahid Babaei, Mehrdad Hashemi, Abbas Doosti, Kiavash Hushmandi, Maliheh Entezari, Saeed Samarghandian
Summary: The combination of curcumin, vitamins D and E with Fe2O3-NPs and MnO2-NPs has shown to improve semen parameters and reduce apoptosis in germ cells in rats with testicular hyperthermia. This study suggests that this combination therapy may have a positive effect on fertility and decreasing the toxic effects of nanoparticles.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
