Microplastics Exacerbate Cadmium-Induced Kidney Injury by Enhancing Oxidative Stress, Autophagy, Apoptosis, and Fibrosis

Comparison of the combined toxicity of polystyrene microplastics and different concentrations of cadmium in zebrafish

(2022) Hui Yang et al.   AQUATIC TOXICOLOGY

Endoplasmic reticulum stress-controlled autophagic pathway promotes polystyrene microplastics-induced myocardial dysplasia in birds

(2022) Yue Zhang et al.   ENVIRONMENTAL POLLUTION

Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis

(2021) Boxuan Liang et al.   Particle and Fibre Toxicology

Effects of nano- and microplastics on kidney: Physicochemical properties, bioaccumulation, oxidative stress and immunoreaction

(2021) Xuemei Meng et al.   CHEMOSPHERE

Investigation of the effects of hesperidin administration on abamectin‐induced testicular toxicity in rats through oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis, autophagy, and JAK2 / STAT3 pathways

(2021) Cihan Gur et al.   ENVIRONMENTAL TOXICOLOGY

Impacts of nanoplastics on bivalve: Fluorescence tracing of organ accumulation, oxidative stress and damage

(2020) Zhenling Li et al.   JOURNAL OF HAZARDOUS MATERIALS

Microplastics from consumer plastic food containers: Are we consuming it?

(2020) Oluniyi O. Fadare et al.   CHEMOSPHERE

Interaction of freshwater microplastics with biota and heavy metals: a review

(2020) Nafiaah Naqash et al.   Environmental Chemistry Letters

Fibers spreading worldwide: Microplastics and other anthropogenic litter in an Arctic freshwater lake

(2020) Miguel González-Pleiter et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Mechanical insights into the regulation of programmed cell death by p53 via mitochondria

(2019) Kohji Yamada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Rosmarinic Acid Attenuates Cadmium-Induced Nephrotoxicity via Inhibition of Oxidative Stress, Apoptosis, Inflammation and Fibrosis

(2019) Swarnalata Joardar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcription Factors and Downstream Genes in Cadmium Toxicity

(2019) Maki Tokumoto et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The behaviour of some antihypertension drugs on human serum paraoxonase‐1: an important protector enzyme against atherosclerosis

(2019) Yeliz Demir   JOURNAL OF PHARMACY AND PHARMACOLOGY

WNT1‐inducible signaling protein‐1 mediates TGF‐β1‐induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy

(2019) Xue Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Curcumin protects the testis against cadmium-induced histopathological damages and oxidative stress in mice

(2019) HR Momeni et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Cadmium induces cytotoxicity through oxidative stress-mediated apoptosis pathway in duck renal tubular epithelial cells

(2019) Jionghan Zhuang et al.   TOXICOLOGY IN VITRO

Microplastic and mesoplastic pollution in farmland soils in suburbs of Shanghai, China

(2018) Mengting Liu et al.   ENVIRONMENTAL POLLUTION

Plastic contamination of the food chain: A threat to human health?

(2018) R.H. Waring et al.   MATURITAS

Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice

(2018) Liang Lu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity

(2018) Pei Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The distribution of microplastics in soil aggregate fractions in southwestern China

(2018) G.S. Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Microplastic particles cause intestinal damage and other adverse effects in zebrafish Danio rerio and nematode Caenorhabditis elegans

(2018) Lili Lei et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Single and combined effects of microplastics and cadmium on the cadmium accumulation, antioxidant defence and innate immunity of the discus fish (Symphysodon aequifasciatus)

(2018) Bin Wen et al.   ENVIRONMENTAL POLLUTION

Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat

(2018) Yushan Cui et al.   TOXICOLOGY LETTERS

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

(2018) Yuanxiang Jin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Toxicity-based toxicokinetic/toxicodynamic assessment for bioaccumulation of polystyrene microplastics in mice

(2018) Ying-Fei Yang et al.   JOURNAL OF HAZARDOUS MATERIALS

Plastic Bag Derived-Microplastics as a Vector for Metal Exposure in Terrestrial Invertebrates

(2017) Mark E. Hodson et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Cadmium disrupts autophagic flux by inhibiting cytosolic Ca 2+ -dependent autophagosome-lysosome fusion in primary rat proximal tubular cells

(2017) Fei Liu et al.   TOXICOLOGY

Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure

(2017) Yongfeng Deng et al.   Scientific Reports

Antioxidants as a Potential Preventive and Therapeutic Strategy for Cadmium

(2016) Malgorzata M. Brzóska et al.   CURRENT DRUG TARGETS

Treatment of cadmium-induced renal oxidative damage in rats by administration of alpha-lipoic acid

(2016) Tongwang Luo et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Sirtuin functions and modulation: from chemistry to the clinic

(2016) Vincenzo Carafa et al.   Clinical Epigenetics

Adsorption of trace metals by microplastic pellets in fresh water

(2015) Andrew Turner et al.   Environmental Chemistry

Soil Contamination in China: Current Status and Mitigation Strategies

(2014) Fang-Jie Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Intracellular Antioxidant Detoxifying Effects of Diosmetin on 2,2-Azobis(2-amidinopropane) Dihydrochloride (AAPH)-Induced Oxidative Stress through Inhibition of Reactive Oxygen Species Generation

(2014) Wenzhen Liao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cadmium induced pathophysiology: Prophylactic role of edible jute (Corchorus olitorius) leaves with special emphasis on oxidative stress and mitochondrial involvement

(2013) Saikat Dewanjee et al.   FOOD AND CHEMICAL TOXICOLOGY

Role of sirtuins in ischemia-reperfusion injury

(2013) Eirini Pantazi   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells

(2011) Yuta Komoike et al.   ARCHIVES OF TOXICOLOGY

Rapamycin Promotes Autophagy and Reduces Neural Tissue Damage and Locomotor Impairment after Spinal Cord Injury in Mice

(2011) Akira Sekiguchi et al.   JOURNAL OF NEUROTRAUMA

Induction of Autophagy and Autophagic Cell Death in Damaged Neural Tissue After Acute Spinal Cord Injury in Mice

(2011) Haruo Kanno et al.   SPINE

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY