Extracellular vesicles released in response to respiratory exposures: implications for chronic disease

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Short-term particulate matter exposure induces extracellular vesicle release in overweight subjects

(2017) Matteo Bonzini et al.   ENVIRONMENTAL RESEARCH

Smoker extracellular vesicles influence status of human bronchial epithelial cells

(2017) Amélie Héliot et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication

(2017) Daniel J. Schneider et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pulmonary toxicity and global gene expression changes in response to sub-chronic inhalation exposure to crystalline silica in rats

(2017) Christina Umbright et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Impact of commercial cigarette smoke condensate on brain tissue co-cultured with astrocytes and blood–brain barrier endothelial cells

(2017) Seon-Bong Lee et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Association between gaseous air pollution and hospital admissions for hypertension in Taipei, Taiwan

(2017) Chih-Cheng Chen et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

From Infections to Anthropogenic Inflicted Pathologies: Involvement of Immune Balance

(2017) Florence Lee et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Bead-based flow-cytometry for semi-quantitative analysis of complex membrane vesicle populations released by bacteria and host cells

(2017) Charlotte Volgers et al.   MICROBIOLOGICAL RESEARCH

Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation

(2017) Laura Pergoli et al.   Particle and Fibre Toxicology

Circulating microvesicle number, function and small RNA content vary with age, gender, smoking status, lipid and hormone profiles

(2017) Anoop K. Enjeti et al.   THROMBOSIS RESEARCH

Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies

(2017) Birke J. Benedikter et al.   Scientific Reports

A bead-assisted flow cytometry method for the semi-quantitative analysis of Extracellular Vesicles

(2017) Henar Suárez et al.   Scientific Reports

Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient MiceSignificance

(2016) Amanda C. Foks et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake

(2016) Erik R. Abels et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Exposure to Fine Particulate Air Pollution Is Associated With Endothelial Injury and Systemic InflammationNovelty and Significance

(2016) C. Arden Pope et al.   CIRCULATION RESEARCH

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

(2016) Michael A. Gimbrone et al.   CIRCULATION RESEARCH

Translocation of Endogenous Danger Signal HMGB1 From Nucleus to Membrane Microvesicles in Macrophages

(2016) Yan Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health—ENPRA Project—The Highlights, Limitations, and Current and Future Challenges

(2016) Ali Kermanizadeh et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

A systematic review of evidence and implications of spatial and seasonal variations of volatile organic compounds (VOC) in indoor human environments

(2016) Inês Paciência et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Expression of exosomal and cellular microRNAs: as biomarkers for toluene, ethylbenzene, xylene (TEX) exposure

(2016) Jung-hee Lim et al.   Molecular & Cellular Toxicology

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistence of circulating endothelial microparticles in COPD despite smoking cessation

(2016) Yael Strulovici-Barel et al.   THORAX

Particulate matter induces prothrombotic microparticle shedding by human mononuclear and endothelial cells

(2016) Tommaso Neri et al.   TOXICOLOGY IN VITRO

Extracellular vesicle-driven information mediates the long-term effects of particulate matter exposure on coagulation and inflammation pathways

(2016) Sofia Pavanello et al.   TOXICOLOGY LETTERS

Tissue factor as a link between inflammation and coagulation

(2016) Marco Witkowski et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Measurements of Deposition, Lung Surface Area and Lung Fluid for Simulation of Inhaled Compounds

(2016) Eleonore Fröhlich et al.   Frontiers in Pharmacology

Amnion-Epithelial-Cell-Derived Exosomes Demonstrate Physiologic State of Cell under Oxidative Stress

(2016) Samantha Sheller et al.   PLoS One

Structural and functional characterization of endothelial microparticles released by cigarette smoke

(2016) Karina A. Serban et al.   Scientific Reports

Effects of secondhand smoke exposure on asthma morbidity and health care utilization in children: a systematic review and meta-analysis

(2015) Zhen Wang et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

European cancer mortality predictions for the year 2015: does lung cancer have the highest death rate in EU women?

(2015) M. Malvezzi et al.   ANNALS OF ONCOLOGY

Inflammatory Diseases of the Lung Induced by Conventional Cigarette Smoke

(2015) Laura E. Crotty Alexander et al.   CHEST

Air Pollution and Cardiovascular Disease

(2015) Barry A. Franklin et al.   CURRENT PROBLEMS IN CARDIOLOGY

Air pollution and public health: emerging hazards and improved understanding of risk

(2015) Frank J. Kelly et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

Cardiovascular effects of ozone in healthy subjects with and without deletion of glutathione-S-transferase M1

(2015) Mark W. Frampton et al.   INHALATION TOXICOLOGY

Angiogenesis in bronchial asthma

(2015) Krzysztof Pałgan et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling

(2015) Emilie Bourdonnay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Methods of isolating extracellular vesicles impact down-stream analyses of their cargoes

(2015) Douglas D. Taylor et al.   METHODS

Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals

(2015) Rodosthenis S. Rodosthenous et al.   Particle and Fibre Toxicology

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Clinical Significance of Tissue Factor–Exposing Microparticles in Arterial and Venous Thrombosis

(2015) Suzanne Bleker et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms

(2015) Chunjun Li et al.   THROMBOSIS AND HAEMOSTASIS

Toluene diisocyanate: Induction of the autotaxin-lysophosphatidic acid axis and its association with airways symptoms

(2015) Julia M. Broström et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Extracellular vesicles in lung microenvironment and pathogenesis

(2015) Yu Fujita et al.   TRENDS IN MOLECULAR MEDICINE

Cigarette Smoke Amplifies Inflammatory Response and Atherosclerosis Progression Through Activation of the H1R-TLR2/4-COX2 Axis

(2015) Rajat S. Barua et al.   Frontiers in Immunology

Smoke exposure as a risk factor for asthma in childhood: A review of current evidence

(2014) Giuliana Ferrante et al.   ALLERGY AND ASTHMA PROCEEDINGS

CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke

(2014) Hyung-Geun Moon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Smoking and Cardiovascular Disease

(2014) Barbara Messner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pathology of human plaque vulnerability: Mechanisms and consequences of intraplaque haemorrhages

(2014) Jean-Baptiste Michel et al.   ATHEROSCLEROSIS

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Microvesicles as Cell–Cell Messengers in Cardiovascular Diseases

(2014) Xavier Loyer et al.   CIRCULATION RESEARCH

Smoking and Atherosclerosis: Mechanisms of Disease and New Therapeutic Approaches

(2014) Gerasimos Siasos et al.   CURRENT MEDICINAL CHEMISTRY

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Rapid shedding of proinflammatory microparticles by human mononuclear cells exposed to cigarette smoke is dependent on Ca2+ mobilization

(2014) Cinzia Cordazzo et al.   INFLAMMATION RESEARCH

Thrombosis: a major contributor to the global disease burden

(2014)   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Outdoor air pollution and asthma

(2014) Michael Guarnieri et al.   LANCET

Occupational Asthma

(2014) Susan M. Tarlo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Obesity and the cardiovascular health effects of fine particulate air pollution

(2014) Scott Weichenthal et al.   Obesity

The Effects of Smoking on Levels of Endothelial Progenitor Cells and Microparticles in the Blood of Healthy Volunteers

(2014) Fariborz Mobarrez et al.   PLoS One

Smoking alters circulating plasma microvesicle pattern and microRNA signatures

(2014) Sigrun Badrnya et al.   THROMBOSIS AND HAEMOSTASIS

The Global Contribution of Outdoor Air Pollution to the Incidence, Prevalence, Mortality and Hospital Admission for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis

(2014) Qingkun Song et al.   International Journal of Environmental Research and Public Health

Quantification and Size-profiling of Extracellular Vesicles Using Tunable Resistive Pulse Sensing

(2014) Sybren L. N. Maas et al.   Jove-Journal of Visualized Experiments

Novel Proteolytic Microvesicles Released from Human Macrophages after Exposure to Tobacco Smoke

(2013) Chun-Jun Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Efferocytosis and Lung Disease

(2013) Alexandra L. McCubbrey et al.   CHEST

Managing tobacco use: the neglected cardiovascular disease risk factor

(2013) N. A. Rigotti et al.   EUROPEAN HEART JOURNAL

Determinants of endothelial function in patients with COPD

(2013) Christian F. Clarenbach et al.   EUROPEAN RESPIRATORY JOURNAL

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

(2013) Bettina Levänen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The biology behind the atherothrombotic effects of cigarette smoke

(2013) Adam Csordas et al.   Nature Reviews Cardiology

50-Year Trends in Smoking-Related Mortality in the United States

(2013) Michael J. Thun et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microparticles: New Protagonists in Pericellular and Intravascular Proteolysis

(2013) Francoise Dignat-George et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Carbon monoxide inhalation increases microparticles causing vascular and CNS dysfunction

(2013) Jiajun Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pulmonary Oxidative Stress, Inflammation and Cancer: Respirable Particulate Matter, Fibrous Dusts and Ozone as Major Causes of Lung Carcinogenesis through Reactive Oxygen Species Mechanisms

(2013) Athanasios Valavanidis et al.   International Journal of Environmental Research and Public Health

Chronic obstructive pulmonary disease and comorbidities

(2013) Marc Decramer et al.   Lancet Respiratory Medicine

Second-Hand Tobacco Smoke and Cardiovascular Disease Risk

(2012) Andrew Dunbar et al.   Cardiology in Review

Effects of outdoor air pollutants on platelet activation in people with type 2 diabetes

(2012) Mark W. Frampton et al.   INHALATION TOXICOLOGY

Cellular biomarkers of endothelial health: microparticles, endothelial progenitor cells, and circulating endothelial cells

(2012) Dylan Burger et al.   Journal of the American Society of Hypertension

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Increased circulating endothelial microparticles in COPD patients: a potential biomarker for COPD exacerbation susceptibility

(2012) Toru Takahashi et al.   THORAX

Thrombogenic changes in young and old mice upon subchronic exposure to air pollution in an urban roadside tunnel

(2012) Jan Emmerechts et al.   THROMBOSIS AND HAEMOSTASIS

Lung microbiology and exacerbations in COPD

(2012) Sebastian Johnston et al.   International Journal of Chronic Obstructive Pulmonary Disease

Circulating Endothelial Microparticles as a Measure of Early Lung Destruction in Cigarette Smokers

(2011) Cynthia Gordon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

RNA-containing Exosomes in Human Nasal Secretions

(2011) Cecilia Lässer et al.   American Journal of Rhinology & Allergy

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy

(2011) Viktoriya Sokolova et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Remodeling in asthma

(2011) Saleh Al-Muhsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A filtration-based protocol to isolate human Plasma Membrane-derived Vesicles and exosomes from blood plasma

(2011) Ryan Grant et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Air pollution-associated procoagulant changes: the role of circulating microvesicles

(2011) J. EMMERECHTS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Fibrotic Response of Tissue Remodeling in COPD

(2011) Lina María Salazar et al.   LUNG

Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles

(2011) Esther N.M. Nolte-'t Hoen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Exosomes as Extrapulmonary Signaling Conveyors for Nanoparticle-Induced Systemic Immune Activation

(2011) Motao Zhu et al.   Small

Tobacco Smoke Induces the Generation of Procoagulant Microvesicles From Human Monocytes/Macrophages

(2010) Mingzhen Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

COPD in Never Smokers

(2010) Bernd Lamprecht et al.   CHEST

Venous Thromboembolism and Atherothrombosis An Integrated Approach

(2010) Gregory Piazza et al.   CIRCULATION

Vascular Effects of Ultrafine Particles in Persons with Type 2 Diabetes

(2010) Judith C. Stewart et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Optical and non-optical methods for detection and characterization of microparticles and exosomes

(2010) E. VAN DER POL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome

(2009) Julie A. Bastarache et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Circulating endothelial cells, microparticles and progenitors: key players towards the definition of vascular competence

(2009) F. Sabatier et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Smoking and venous thromboembolism: a Danish follow-up study

(2009) M. T. SEVERINSEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Chronic obstructive pulmonary disease in non-smokers

(2009) Sundeep S Salvi et al.   LANCET

Brief Secondhand Smoke Exposure Depresses Endothelial Progenitor Cells Activity and Endothelial Function

(2008) Christian Heiss et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY