Fibrotic Response of Tissue Remodeling in COPD

Airway smooth muscle remodels pericellular collagen fibrils: implications for proliferation

(2010) Michael Schuliga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

FGF-1 reverts epithelial-mesenchymal transition induced by TGF-β1 through MAPK/ERK kinase pathway

(2010) Carlos Ramos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Fibrogenic Reactions in Lung Disease

(2010) Jun Araya et al.   Annual Review of Pathology-Mechanisms of Disease

Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12in a European population

(2010) Imran Haq et al.   BMC Medical Genetics

Pathological airway remodelling in inflammation

(2010) Gunilla Westergren-Thorsson et al.   Clinical Respiratory Journal

Extensive Analysis of Elastase-Induced Pulmonary Emphysema in Rats: ALP in the Lung, a New Biomarker for Disease Progression?

(2010) Ken-ichiro Inoue et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Comorbidity, Hospitalization, and Mortality in COPD: Results from a Longitudinal Study

(2010) Claudio Terzano et al.   LUNG

Polymorphisms in Matrix Metalloproteinase-1, -9 and -12 Genes and the Risk of Chronic Obstructive Pulmonary Disease in a Korean Population

(2010) Shin-Yup Lee et al.   RESPIRATION

Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: A potential model of goblet cell hyperplasia

(2010) Linsey E. Haswell et al.   TOXICOLOGY IN VITRO

Elevation of sputum matrix metalloproteinase-9 persists up to 6 months after smoking cessation: a research study

(2010) Noora Louhelainen et al.   BMC Pulmonary Medicine

Matrix Metalloproteinase-14 Mediates a Phenotypic Shift in the Airways to Increase Mucin Production

(2009) Hitesh S. Deshmukh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Insulin-Induced Laminin Expression Promotes a Hypercontractile Airway Smooth Muscle Phenotype

(2009) Bart G. J. Dekkers et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia

(2009) Luigi Atzori et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Enhanced Deposition of Low-Molecular-Weight Hyaluronan in Lungs of Cigarette Smoke–Exposed Mice

(2009) Ken R. Bracke et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genetic Polymorphisms of Cytochrome P450 and Matrix Metalloproteinase in Chronic Obstructive Pulmonary Disease

(2009) Shih-Lung Cheng et al.   BIOCHEMICAL GENETICS

The ‘sweet’ and ‘bitter’ involvement of glycosaminoglycans in lung diseases: pharmacotherapeutic relevance

(2009) Eleni Papakonstantinou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Matrix Metalloproteinase 12 Overexpression in Lung Epithelial Cells Plays a Key Role in Emphysema to Lung Bronchioalveolar Adenocarcinoma Transition

(2009) P. Qu et al.   CANCER RESEARCH

Bronchial Airway Epithelial Cell Damage Following Exposure to Cigarette Smoke Includes Disassembly of Tight Junction Components Mediated by the Extracellular Signal-Regulated Kinase 1/2 Pathway

(2009) Loredana Petecchia et al.   CHEST

Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD

(2009) I. Klagas et al.   EUROPEAN RESPIRATORY JOURNAL

Matrix metalloproteinase gene polymorphisms: lack of association with chronic obstructive pulmonary disease in a Brazilian population

(2009) H. Schirmer et al.   GENETICS AND MOLECULAR RESEARCH

TGF-β1 Induces Human Bronchial Epithelial Cell-to-Mesenchymal Transition in Vitro

(2009) Min Zhang et al.   LUNG

MMP12,Lung Function, and COPD in High-Risk Populations

(2009) Gary M. Hunninghake et al.   NEW ENGLAND JOURNAL OF MEDICINE

N-acetyl-l-cysteine inhibits TGF-β1-induced profibrotic responses in fibroblasts

(2009) Hisatoshi Sugiura et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Bronchial vascular remodelling in patients with COPD and its relationship with inhaled steroid treatment

(2009) A Zanini et al.   THORAX

Ultrastructural Features of Lung Fibroblast Differentiation into Myofibroblasts

(2009) Riitta Kaarteenaho-Wiik et al.   ULTRASTRUCTURAL PATHOLOGY

Matrix metalloprotease polymorphisms are associated with gas transfer in alpha 1 antitrypsin deficiency

(2009) Christopher J. McAloon et al.   Therapeutic Advances in Respiratory Disease

Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease

(2008) Ann E. Tilley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Expression of Profibrotic Mediators in Small Airways versus Parenchyma after Cigarette Smoke Exposure

(2008) Andrew Churg et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Pathology of Chronic Obstructive Pulmonary Disease

(2008) James C. Hogg et al.   Annual Review of Pathology-Mechanisms of Disease

Matrix Metalloproteinase Expression by Human Alveolar Macrophages in Relation to Emphysema

(2008) Alison M. Wallace et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction

(2008) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

Pulmonary hypertension in COPD

(2008) A. Chaouat et al.   EUROPEAN RESPIRATORY JOURNAL

Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis

(2008) Annika Andersson-Sjöland et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MMP-9 protein level does not reflect overall MMP activity in the airways of patients with COPD

(2008) Gillian E. Lowrey et al.   RESPIRATORY MEDICINE

Airway Smooth Muscle in Bronchial Tone, Inflammation, and Remodeling

(2007) Reynold A. Panettieri et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY