Platelets contribute to the initiation of colitis-associated cancer by promoting immunosuppression

Frontline Science: Myeloid cell-specific deletion of Cebpb decreases sepsis-induced immunosuppression in mice

(2017) Melissa B. McPeak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides

(2017) C. Delierneux et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2 and Cytokines

(2017) Bona Linke et al.   MEDIATORS OF INFLAMMATION

The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane- and dextran sulfate sodium-treated CF-1 mice

(2016) Yue Guo et al.   CARCINOGENESIS

Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults

(2016) Mieke Buck et al.   CURRENT MEDICINAL CHEMISTRY

Myeloid-derived suppressor cells in gastrointestinal cancers: A systematic review

(2016) Armin Hirbod-Mobarakeh et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Myeloid-Derived Suppressor Cells in Cancers and Inflammatory Diseases: Angel or Demon?

(2016) Z. Su et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers

(2016) Wenbin Li et al.   Protein & Cell

Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients

(2016) Salman M. Toor et al.   Frontiers in Immunology

Haptoglobin Enhances Cardiac Transplant Rejection

(2015) H. Shen et al.   CIRCULATION RESEARCH

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

(2015) Seth B. Coffelt et al.   NATURE

Clopidogrel use and cancer-specific mortality: a population-based cohort study of colorectal, breast and prostate cancer patients

(2015) Blánaid M. Hicks et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Effect of P2Y12 inhibitors on inflammation and immunity

(2015) Robert Storey et al.   THROMBOSIS AND HAEMOSTASIS

The role of platelets in inflammation

(2015) Robert Storey et al.   THROMBOSIS AND HAEMOSTASIS

Platelet microparticles and cancer: An intimate cross-talk

(2015) Hadi Goubran et al.   TRANSFUSION AND APHERESIS SCIENCE

Phenotypic Diversity and Plasticity in Circulating Neutrophil Subpopulations in Cancer

(2015) Jitka Y. Sagiv et al.   Cell Reports

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function

(2015) Eunyoung Chun et al.   Cell Reports

MyeloidSTAT3promotes formation of colitis-associated colorectal cancer in mice

(2015) Paulina Pathria et al.   OncoImmunology

Phenotype, development, and biological function of myeloid-derived suppressor cells

(2015) Yang Zhao et al.   OncoImmunology

Colorectal cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasisin vivo

(2014) Soraya Mezouar et al.   INTERNATIONAL JOURNAL OF CANCER

Platelets Effects on Tumor Growth

(2014) Hadi A. Goubran et al.   SEMINARS IN ONCOLOGY

Effects of Cancer on Platelets

(2014) Nick van Es et al.   SEMINARS IN ONCOLOGY

Thrombocytosis as a prognostic marker in gastrointestinal cancers

(2014) Ioannis A Voutsadakis   World Journal of Gastrointestinal Oncology

CXCR2-Expressing Myeloid-Derived Suppressor Cells Are Essential to Promote Colitis-Associated Tumorigenesis

(2013) Hiroshi Katoh et al.   CANCER CELL

Platelet Abnormalities during Colonic Inflammation

(2013) Serena L. S. Yan et al.   INFLAMMATORY BOWEL DISEASES

Characterization of the thrombin generation potential of leukemic and solid tumor cells by calibrated automated thrombography

(2012) M. Marchetti et al.   HAEMATOLOGICA

Biomarkers of inflammation are associated with colorectal cancer risk in women but are not suitable as early detection markers

(2012) Adetunji T. Toriola et al.   INTERNATIONAL JOURNAL OF CANCER

The Dual Role of Inflammation in Colon Carcinogenesis

(2012) Giovanni Monteleone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing

(2011) W. Feng et al.   BLOOD

Intestinal Inflammation and Cancer

(2011) Thomas A. Ullman et al.   GASTROENTEROLOGY

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

(2010) Ilaria Marigo et al.   IMMUNITY

Enhanced platelet adhesion induces angiogenesis in intestinal inflammation and inflammatory bowel disease microvasculature

(2010) Sergio Rutella et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A

(2010) Carmela De Santo et al.   NATURE IMMUNOLOGY

Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function

(2010) Thomas Condamine et al.   TRENDS IN IMMUNOLOGY

The acute phase protein haptoglobin regulates host immunity

(2008) Kristin M. Huntoon et al.   JOURNAL OF LEUKOCYTE BIOLOGY