JTC-801 exerts anti-proliferative effects in human osteosarcoma cells by inducing apoptosis

Effects of Spiro-bisheterocycles on Proliferation and Apoptosis in Human Breast Cancer Cell Lines

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(2016) Hye-Eun Choi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Diallyl trisulfide induces osteosarcoma cell apoptosis through reactive oxygen species-mediated downregulation of the PI3K/Akt pathway

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GPR171 expression enhances proliferation and metastasis of lung cancer cells

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(2016) Linda S. Steelman et al.   Aging-US

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(2015) Artem Kondratskyi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

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PI3K/AKT signaling pathway and cancer: an updated review

(2014) Miriam Martini et al.   ANNALS OF MEDICINE

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(2014) Marieke L Kuijjer et al.   BMC Medical Genomics

Nociceptin/orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of post-traumatic stress disorder

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(2014) Raimundo Fernandes de Araújo Júnior et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Structure and function of G protein-coupled receptor oligomers: implications for drug discovery

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Eicosapentaenoic acid attenuated oxidative stress-induced cardiomyoblast apoptosis by activating adaptive autophagy

(2013) Hsiu-Ching Hsu et al.   EUROPEAN JOURNAL OF NUTRITION

Curcumin induces osteosarcoma MG63 cells apoptosis via ROS/Cyto-C/Caspase-3 pathway

(2013) Zhengqi Chang et al.   TUMOR BIOLOGY

Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Differential effects of Bcl-2 and caspases on mitochondrial permeabilization during endogenous or exogenous reactive oxygen species-induced cell death

(2012) Vincent Rincheval et al.   CELL BIOLOGY AND TOXICOLOGY

The PI3K/AKT/mTOR Pathway as a Therapeutic Target in Endometrial Cancer

(2012) B. M. Slomovitz et al.   CLINICAL CANCER RESEARCH

Direct Induction of Apoptosis Using an Optimal Mitochondrially Targeted p53

(2012) Mohanad Mossalam et al.   MOLECULAR PHARMACEUTICS

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High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes

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Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

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Proliferation and Apoptosis in Aged and Photoregressed Mammalian Seminiferous Epithelium, with Particular Attention to Rodents and Humans

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Nociceptin receptor antagonist JTC-801 inhibits nitrous oxide-induced analgesia in mice

(2009) Tomohiro Koyama et al.   Journal of Anesthesia

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(2008) M J Lohse et al.   BRITISH JOURNAL OF PHARMACOLOGY

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(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Therapy for Osteosarcoma

(2008) Alexander J Chou et al.   PEDIATRIC DRUGS