Nociceptin/orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of post-traumatic stress disorder

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence

(2013) Jeffrey M. Witkin et al.   PHARMACOLOGY & THERAPEUTICS

Amygdala-Dependent Fear Is Regulated by Oprl1 in Mice and Humans with PTSD

(2013) R. Andero et al.   Science Translational Medicine

Murine model of repeated exposures to conspecific trained aggressors simulates features of post-traumatic stress disorder

(2012) Rasha Hammamieh et al.   BEHAVIOURAL BRAIN RESEARCH

Role of Nociceptin/Orphanin FQ and NOP Receptors in the Response to Acute and Repeated Restraint Stress in Rats

(2012) G. Delaney et al.   JOURNAL OF NEUROENDOCRINOLOGY

Increased Nociceptive Sensitivity and Nociceptin/Orphanin FQ Levels in a Rat Model of PTSD

(2012) Yong Zhang et al.   Molecular Pain

Further characterization of the prototypical nociceptin/orphanin FQ peptide receptor agonist Ro 64-6198 in rodent models of conflict anxiety and despair

(2012) Celia Goeldner et al.   PSYCHOPHARMACOLOGY

Effect of stress on hippocampal nociceptin expression in the rat

(2012) Paola Nativio et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Anxiolytic-like effect of central administration of NOP receptor antagonist UFP-101 in rats submitted to the elevated T-maze

(2011) Marcelo Duzzioni et al.   BEHAVIOURAL BRAIN RESEARCH

Synthesis and pharmacological evaluation of bivalent antagonists of the nociceptin opioid receptor

(2011) Maria Rosaria Del Giudice et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): Comparison of efficacy and side effects across rodent species

(2011) Sherry X. Lu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Elevated prepronociceptin, nociceptin/orphanin FQ and nocistatin concentrations in rat chronic constriction nerve injury and diabetic neuropathic pain models

(2011) Eugene H. Liu et al.   NEUROSCIENCE LETTERS

Synergistic anti-allodynic effects of nociceptin/orphanin FQ and cannabinoid systems in neuropathic mice

(2011) Ozgur Gunduz et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Central nociceptin/orphanin FQ system elevates food consumption by both increasing energy intake and reducing aversive responsiveness

(2010) Pawel K. Olszewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Understanding the co-occurrence of anxiety disorders and chronic pain: state-of-the-art

(2009) Gordon J.G. Asmundson et al.   DEPRESSION AND ANXIETY

Single prolonged stress: toward an animal model of posttraumatic stress disorder

(2009) Shigeto Yamamoto et al.   DEPRESSION AND ANXIETY

An Association Between Stress-Induced Disruption of the Hypothalamic-Pituitary-Adrenal Axis and Disordered Glucose Metabolism in an Animal Model of Post-Traumatic Stress Disorder

(2009) H. Cohen et al.   JOURNAL OF NEUROENDOCRINOLOGY

Social defeat stress produces prolonged alterations in acoustic startle and body weight gain in male Long Evans rats

(2009) John V.K. Pulliam et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Prevalence of chronic pain, posttraumatic stress disorder, and persistent postconcussive symptoms in OIF/OEF veterans: Polytrauma clinical triad

(2009) Henry L. Lew et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain

(2009) Giovanna M. Scoto et al.   LIFE SCIENCES

Nociceptin/orphanin FQ and NOP receptor gene regulation after acute or repeated social defeat stress

(2009) Megan K. Green et al.   NEUROPEPTIDES

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

(2008) David G. Lambert   NATURE REVIEWS DRUG DISCOVERY

Role of amygdaloid nuclei in the anxiolytic-like effect of nociceptin/orphanin FQ in rats

(2007) Hidemori Uchiyama et al.   NEUROSCIENCE LETTERS