Melatonin attenuates osteosarcoma cell invasion by suppression of C-C motif chemokine ligand 24 through inhibition of the c-Jun N-terminal kinase pathway

Radiotherapy in the Treatment of Primary Osteosarcoma – a Single Center Experience

(2018) Susanne Oertel et al.   TUMORI

Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis

(2017) Russel Reiter et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin as a potential inhibitory agent in head and neck cancer

(2017) Chia-Ming Yeh et al.   Oncotarget

Inhibition of ERK1/2 Signaling Pathway is Involved in Melatonin's Antiproliferative Effect on Human MG-63 Osteosarcoma Cells

(2016) Lifeng Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Tricetin inhibits human osteosarcoma cells metastasis by transcriptionally repressing MMP-9 via p38 and Akt pathways

(2016) Pin-Yu Chang et al.   ENVIRONMENTAL TOXICOLOGY

3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo

(2016) Ko-Hsiu Lu et al.   FOOD AND CHEMICAL TOXICOLOGY

Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity

(2016) Yung-Wei Lin et al.   JOURNAL OF PINEAL RESEARCH

Melatonin suppresses TPA-induced metastasis by downregulating matrix metalloproteinase-9 expression through JNK/SP-1 signaling in nasopharyngeal carcinoma

(2016) Hsin-Yu Ho et al.   JOURNAL OF PINEAL RESEARCH

Cancer metastasis: Mechanisms of inhibition by melatonin

(2016) Shih-Chi Su et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Melatonin/HPβCD complex: Microwave synthesis, integration with chitosan scaffolds and inhibitory effects on MG-63CELLS

(2015) Bedriye Topal et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Melatonin Cytotoxicity Is Associated to Warburg Effect Inhibition in Ewing Sarcoma Cells

(2015) Ana M. Sanchez-Sanchez et al.   PLoS One

Extrapineal melatonin: sources, regulation, and potential functions

(2014) Darío Acuña-Castroviejo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L

(2014) Ilona Kryczek et al.   IMMUNITY

Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells

(2014) Yunkyung Hong et al.   JOURNAL OF PINEAL RESEARCH

Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways

(2014) Hongsheng Lu et al.   TUMOR BIOLOGY

Melatonin Attenuates Her-2, p38 MAPK, p-AKT, and mTOR Levels in Ovarian Carcinoma of Ethanol-Preferring Rats

(2014) Grazielle M. Ferreira et al.   Journal of Cancer

PI3K, ERK, p38 MAPK and integrins regulate CCR3-mediated secretion of mouse and human eosinophil-associated RNases

(2013) R. Shamri et al.   ALLERGY

Melatonin inhibits the proliferation of human osteosarcoma cell line MG-63

(2013) Lifeng Liu et al.   BONE

Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells

(2013) S Carbajo-Pescador et al.   BRITISH JOURNAL OF CANCER

SIRT1 inhibition by melatonin exerts antitumor activity in human osteosarcoma cells

(2013) Yedong Cheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular mechanisms of the pro-apoptotic actions of melatonin in cancer: a review

(2013) Mariano Bizzarri et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Selaginella tamariscina (Beauv.) possesses antimetastatic effects on human osteosarcoma cells by decreasing MMP-2 and MMP-9 secretions via p38 and Akt signaling pathways

(2013) Jia-Sin Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibition of matrix metalloproteinase-9 and nuclear factor kappa B contribute to melatonin prevention of motility and invasiveness in HepG2 liver cancer cells

(2013) Raquel Ordoñez et al.   JOURNAL OF PINEAL RESEARCH

The role of melatonin in the cells of the innate immunity: a review

(2013) Juan R. Calvo et al.   JOURNAL OF PINEAL RESEARCH

Fas/Fas ligand regulation mediates cell death in human Ewing's sarcoma cells treated with melatonin

(2012) G García-Santos et al.   BRITISH JOURNAL OF CANCER

Elevated Plasma Cytokines in Japanese Patients with Eosinophilic Esophagitis and Gastroenteritis

(2012) Yoshikazu Kinoshita et al.   DIGESTION

Phyllanthus urinaria suppresses human osteosarcoma cell invasion and migration by transcriptionally inhibiting u-PA via ERK and Akt signaling pathways

(2012) Ko-Hsiu Lu et al.   FOOD AND CHEMICAL TOXICOLOGY

A beginner’s guide to chemokines

(2012) Victoria Vinader et al.   Future Medicinal Chemistry

Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells

(2012) Juntao Wang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin inhibits cell proliferation and induces caspase activation and apoptosis in human malignant lymphoid cell lines

(2012) Marina Sánchez-Hidalgo et al.   JOURNAL OF PINEAL RESEARCH

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

(2012) Jingshu Wang et al.   JOURNAL OF PINEAL RESEARCH

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Basic Mechanisms Involved in the Anti-Cancer Effects of Melatonin

(2011) M. D. Mediavilla et al.   CURRENT MEDICINAL CHEMISTRY

Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science

(2011) D.-X. Tan et al.   JOURNAL OF EXPERIMENTAL BOTANY

mtDNA T8993G mutation-induced mitochondrial complex V inhibition augments cardiolipin-dependent alterations in mitochondrial dynamics during oxidative, Ca2+, and lipid insults in NARP cybrids: a potential therapeutic target for melatonin

(2011) Tsung-I Peng et al.   JOURNAL OF PINEAL RESEARCH

Interleukin-13 directly promotes oesophagus production of CCL11 and CCL24 and the migration of eosinophils

(2010) C. V. Neilsen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Analysis of eotaxin 1/CCL11, eotaxin 2/CCL24 and eotaxin 3/CCL26 expression in lesional and non-lesional skin of patients with atopic dermatitis

(2010) Witold Owczarek et al.   CYTOKINE

Matrix metalloproteinases in health and disease: regulation by melatonin

(2010) Snehasikta Swarnakar et al.   JOURNAL OF PINEAL RESEARCH

DEGseq: an R package for identifying differentially expressed genes from RNA-seq data

(2009) Likun Wang et al.   BIOINFORMATICS

Osteosarcoma incidence and survival rates from 1973 to 2004

(2009) Lisa Mirabello et al.   CANCER

Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer

(2009) Bernhard Mlecnik et al.   GASTROENTEROLOGY

International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons

(2009) Lisa Mirabello et al.   INTERNATIONAL JOURNAL OF CANCER

ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration

(2008) Leonardo Ortíz-López et al.   JOURNAL OF PINEAL RESEARCH

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS