3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo

Published 2016 View Full Article

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Title
3-Hydroxyflavone inhibits human osteosarcoma U2OS and 143B cells metastasis by affecting EMT and repressing u-PA/MMP-2 via FAK-Src to MEK/ERK and RhoA/MLC2 pathways and reduces 143B tumor growth in vivo
Authors
Keywords
FAK-Src, MEK/ERK, Metastasis, Osteosarcoma, RhoA/MLC2, 3-Hydroxyflavone
Journal
FOOD AND CHEMICAL TOXICOLOGY
Volume 97, Issue -, Pages 177-186
Publisher
Elsevier BV
Online
2016-09-09
DOI
10.1016/j.fct.2016.09.006

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