Monocyte-derived hepatocyte-like cells for causality assessment of idiosyncratic drug-induced liver injury

Drug-induced liver injury: results from the hospital-based Berlin Case-Control Surveillance Study

(2015) Antonios Douros et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

(2014) Naga P Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Mechanisms of drug-induced liver injury

(2014) Camilla Stephens et al.   Current Opinion in Allergy and Clinical Immunology

Methodology to Assess Clinical Liver Safety Data

(2014) Michael Merz et al.   DRUG SAFETY

Liver Safety Assessment: Required Data Elements and Best Practices for Data Collection and Standardization in Clinical Trials

(2014) Mark I. Avigan et al.   DRUG SAFETY

Evolution of the Food and Drug Administration Approach to Liver Safety Assessment for New Drugs: Current Status and Challenges

(2014) John R. Senior   DRUG SAFETY

Liver Safety Assessment in Special Populations (Hepatitis B, C, and Oncology Trials)

(2014) Gerd A. Kullak-Ublick et al.   DRUG SAFETY

Drug-Induced Liver Injury: Morbidity, Mortality, and Hy’s Law

(2014) Arie Regev et al.   GASTROENTEROLOGY

Use of Hy's Law and a New Composite Algorithm to Predict Acute Liver Failure in Patients With Drug-Induced Liver Injury

(2014) Mercedes Robles–Diaz et al.   GASTROENTEROLOGY

Infiltrating Monocyte-Derived Macrophages and Resident Kupffer Cells Display Different Ontogeny and Functions in Acute Liver Injury

(2014) E. Zigmond et al.   JOURNAL OF IMMUNOLOGY

Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug-Induced Liver Injury Network (DILIN)

(2014) Paul H. Hayashi et al.   LIVER INTERNATIONAL

Drug-Induced Liver Injury and Drug Development: Industry Perspective

(2014) Arie Regev   SEMINARS IN LIVER DISEASE

Drug-induced Acute Liver Failure

(2013) William M. Lee   Clinics in Liver Disease

Mechanisms of Drug-induced Liver Injury

(2013) Liyun Yuan et al.   Clinics in Liver Disease

Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland

(2013) Einar S. Björnsson et al.   GASTROENTEROLOGY

Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis

(2013) Mitchell R. McGill et al.   PHARMACEUTICAL RESEARCH

LiverTox: A website on drug-induced liver injury

(2012) Jay H. Hoofnagle et al.   HEPATOLOGY

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

(2012) Mitchell R. McGill et al.   JOURNAL OF CLINICAL INVESTIGATION

Human monocyte-derived cells with individual hepatocyte characteristics: a novel tool for personalized in vitro studies

(2012) Andreas Benesic et al.   LABORATORY INVESTIGATION

Genetic variations in drug-induced liver injury (DILI): resolving the puzzle

(2012) Camilla Stephens et al.   Frontiers in Genetics

Case Definition and Phenotype Standardization in Drug-Induced Liver Injury

(2011) G P Aithal et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Opportunities for Use of Human iPS Cells in Predictive Toxicology

(2011) B D Anson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Causality assessment methods in drug induced liver injury: Strengths and weaknesses

(2011) Miren García-Cortés et al.   JOURNAL OF HEPATOLOGY

Important Elements for the Diagnosis of Drug-Induced Liver Injury

(2010) Vijay K. Agarwal et al.   Clinical Gastroenterology and Hepatology

In Vitro Evaluation of Potential Hepatotoxicity Induced by Drugs

(2010) M.J. Gomez-Lechon et al.   CURRENT PHARMACEUTICAL DESIGN

Causality assessment in drug-induced liver injury using a structured expert opinion process: Comparison to the Roussel-Uclaf causality assessment method

(2010) Don C. Rockey et al.   HEPATOLOGY

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

Mechanisms of Immune-Mediated Liver Injury

(2010) David H. Adams et al.   TOXICOLOGICAL SCIENCES

The future of drug safety testing: expanding the view and narrowing the focus

(2009) James L. Stevens et al.   DRUG DISCOVERY TODAY

Diagnosis, management and prevention of drug-induced liver injury

(2009) S Verma et al.   GUT

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

(2008) Naga Chalasani et al.   GASTROENTEROLOGY