Chimeric antigen receptor (CAR)-engineered T cells redirected against hepatitis C virus (HCV) E2 glycoprotein

HCV E2 core structures and mAbs: something is still missing

(2014) Matteo Castelli et al.   DRUG DISCOVERY TODAY

HCV animal models and liver disease

(2014) Koen Vercauteren et al.   JOURNAL OF HEPATOLOGY

Hepatitis C treatment: an incipient therapeutic revolution

(2014) Andrew S. deLemos et al.   TRENDS IN MOLECULAR MEDICINE

Hepatitis C Virus Cell-Cell Transmission and Resistance to Direct-Acting Antiviral Agents

(2014) Fei Xiao et al.   PLoS Pathogens

Human Hepatocytes and Hematolymphoid Dual Reconstitution in Treosulfan-Conditioned uPA-NOG Mice

(2013) Tanuja L. Gutti et al.   AMERICAN JOURNAL OF PATHOLOGY

New Insights in Recurrent HCV Infection after Liver Transplantation

(2013) Shih-Hsien Hsu et al.   Clinical & Developmental Immunology

Peptide-Based Vaccinology: Experimental and Computational Approaches to Target Hypervariable Viruses through the Fine Characterization of Protective Epitopes Recognized by Monoclonal Antibodies and the Identification of T-Cell-Activating Peptides

(2013) Matteo Castelli et al.   Clinical & Developmental Immunology

Structural and Antigenic Definition of Hepatitis C Virus E2 Glycoprotein Epitopes Targeted by Monoclonal Antibodies

(2013) Giuseppe Sautto et al.   Clinical & Developmental Immunology

T Cells Expressing a Chimeric Antigen Receptor That Binds Hepatitis B Virus Envelope Proteins Control Virus Replication in Mice

(2013) Karin Krebs et al.   GASTROENTEROLOGY

An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission

(2013) Alexander W. Tarr et al.   HEPATOLOGY

Epidemiology and natural history of HCV infection

(2013) Behzad Hajarizadeh et al.   Nature Reviews Gastroenterology & Hepatology

CD19 CAR-Targeted T Cells Induce Long-Term Remission and B Cell Aplasia in an Immunocompetent Mouse Model of B Cell Acute Lymphoblastic Leukemia

(2013) Marco L. Davila et al.   PLoS One

Antigen-Specific T-Cell Activation Independently of the MHC: Chimeric Antigen Receptor-Redirected T Cells

(2013) Markus Chmielewski et al.   Frontiers in Immunology

Anti-hepatitis C virus E2 (HCV/E2) glycoprotein monoclonal antibodies and neutralization interference

(2012) Giuseppe Sautto et al.   ANTIVIRAL RESEARCH

HCV Proteins and Immunoglobulin Variable Gene (IgV) Subfamilies in HCV-Induced Type II Mixed Cryoglobulinemia: A Concurrent Pathogenetic Role

(2012) Giuseppe Sautto et al.   Clinical & Developmental Immunology

Neutralization Interfering Antibodies: A “Novel” Example of Humoral Immune Dysfunction Facilitating Viral Escape?

(2012) Mancini Nicasio et al.   Viruses-Basel

The Role of Humoral Innate Immunity in Hepatitis C Virus Infection

(2012) Alexander W. Tarr et al.   Viruses-Basel

Molecular Signatures of Hepatitis C Virus (HCV)-Induced Type II Mixed Cryoglobulinemia (MCII)

(2012) Giuseppe Sautto et al.   Viruses-Basel

A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease

(2011) Michael L. Washburn et al.   GASTROENTEROLOGY

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolving epidemiology of hepatitis C virus

(2010) D. Lavanchy   CLINICAL MICROBIOLOGY AND INFECTION

Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission

(2010) C. L. Brimacombe et al.   JOURNAL OF VIROLOGY

HCV+ Hepatocytes Induce Human Regulatory CD4+ T Cells through the Production of TGF-β

(2010) Caroline H. T. Hall et al.   PLoS One

Transduction of Human T Cells with a Novel T-Cell Receptor Confers Anti-HCV Reactivity

(2010) Yi Zhang et al.   PLoS Pathogens

Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells

(2009) C. J. Mee et al.   JOURNAL OF VIROLOGY

Chimeric Antigen Receptors Combining 4-1BB and CD28 Signaling Domains Augment PI3kinase/AKT/Bcl-XL Activation and CD8+ T Cell–mediated Tumor Eradication

(2009) Xiao-Song Zhong et al.   MOLECULAR THERAPY

Hepatitis C Virus (HCV) Infection May Elicit Neutralizing Antibodies Targeting Epitopes Conserved in All Viral Genotypes

(2009) Nicasio Mancini et al.   PLoS One

Hepatitis C virus (HCV)-driven stimulation of subfamily-restricted natural IgM antibodies in mixed cryoglobulinemia

(2008) Mario Perotti et al.   AUTOIMMUNITY REVIEWS

T Cells Redirected Against Hepatitis B Virus Surface Proteins Eliminate Infected Hepatocytes

(2008) Felix Bohne et al.   GASTROENTEROLOGY

Perspectives for the utilization of neutralizing human monoclonal antibodies as anti-HCV drugs

(2008) Roberto Burioni et al.   JOURNAL OF HEPATOLOGY