Article
Engineering, Biomedical
Amin Komeili, Baaba Sekyiwaa Otoo, Ziad Abusara, Scott Sibole, Salvatore Federico, Walter Herzog
Summary: This study investigated the dynamic deformations of chondrocytes during compressive loading, revealing volume loss in early compression and cell deformation with minimal volume loss in late compression. During stress relaxation post-compression, force continued to decrease while chondrocyte shape/volume remained unchanged after the first minute.
ANNALS OF BIOMEDICAL ENGINEERING
(2021)
Article
Engineering, Biomedical
Kimberly R. Kroupa, Lianna R. Gangi, Brandon K. Zimmerman, Clark T. Hung, Gerard A. Ateshian
Summary: Recent studies have shown that superficial zone chondrocytes within ar-ticular layers of diarthrodial joints die under normal physiologic loading conditions. In order to understand the mechanical environment that causes their death, a multiscale finite element analysis was conducted to track the changes in interstitial fluid pressure, hydraulic permeability, and volume of SZ chondrocytes under loading. The results indicated that sustained physiological loading can lead to significant loss of intracellular fluid volume, hindering cellular metabolic activity and fluid transport properties.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Civil
Alireza Mohammadinia, Parisa Rahimzadeh Oskooei, Arul Arulrajah
Summary: A numerical model was developed to simulate the macro- and micromechanical properties of lightly cement stabilized recycled concrete aggregates. The results showed that the model performed well in estimating the stress-strain behavior of cemented RCA samples and changes in void ratio.
TRANSPORTATION GEOTECHNICS
(2021)
Article
Engineering, Geological
Amirsalar Moslehy, Khalid Alshibli
Summary: This study investigated the compression behavior of polycrystalline rock salt under different water contents and its effects on physical and mechanical properties. The relationship between porosity and applied stresses during compression was found to be linear with unique critical porosities. Annealing of the specimens impacted both porosity and compressive strength, with wet specimens showing lower porosity but decreased strength compared to dry specimens.
JOURNAL OF ROCK MECHANICS AND GEOTECHNICAL ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Dasen Xu, Nu Zhang, Sijie Wang, Pan Zhang, Yulong Li, Hui Yang
Summary: Changes in the mechanical properties of single cells are associated with their physiological state and fate. The construction of cell constitutive equations is crucial for understanding the material characteristics of single cells. Recent research using technologies such as atomic force microscopy and bio-image processing algorithms has led to rapid advancements in understanding the mechanical properties of cells in static/quasi-static processes. Dynamic stress-strain relations are vital for completing the constitutive equations of living cells. A novel method for generating controllable dynamical compression shear coupling stress on living cells is proposed in this study.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Materials Science, Composites
Xinyue Zhang, Yu Zhang, Mingjin Wu, Kai Chen, Cunao Feng, Xiaowei Li, Dekun Zhang
Summary: Human articular cartilage is a nonlinear, viscoelastic tissue with different mechanical properties and functions in different layers. The compression properties can predict cartilage integrity and osteoarthritis likelihood. Study shows that the deformation rate of each cartilage layer varies under different loading conditions.
JOURNAL OF THERMOPLASTIC COMPOSITE MATERIALS
(2023)
Article
Orthopedics
Andreas Martin Seitz, Florian Schall, Steffen Paul Hacker, Stefan van Drongelen, Sebastian Wolf, Lutz Duerselen
Summary: This study investigated the impact of physiological muscle force simulation on anterior meniscus attachment forces, leading to significantly higher strains and forces compared to uniaxial loading conditions. The presence of a longitudinal tear or meniscectomy further increased the attachment strains and forces.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2021)
Article
Engineering, Biomedical
Zhaonan Sun, Sang-Hyun Lee, Bronislaw D. Gepner, Joshua Rigby, Jason J. Hallman, Jason R. Kerrigan
Summary: This study examined the mechanical response of human and porcine adipose tissue, finding that porcine adipose tissue is significantly stiffer than human adipose tissue under compression and shear loading. The material response of human adipose tissue was consistent with previous studies, while porcine adipose tissue showed a poor fit when material model parameters were fit to only one loading mode.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Engineering, Biomedical
Bobby Carroll, Minh-Tri Ho Thanh, Alison E. Patteson
Summary: The mechanical properties of tissues are crucial for tissue development and maintenance. By studying the mechanical behavior of fibrous networks embedded with stiff beads, it is found that the presence of beads enhances the mechanical performance of the network under compression, possibly due to the hindrance of network relaxation.
ACTA BIOMATERIALIA
(2023)
Article
Materials Science, Multidisciplinary
Lanxi Feng, Wanghui Li, Eric N. Hahn, Paulo S. Branicio, Xiaoqing Zhang, Xiaohu Yao
Summary: The study investigates the dynamic behavior of silicon carbide (SiC) under extreme conditions through large-scale molecular dynamics simulations. Under intense shock compression, SiC undergoes various phases including elastic wave, elastic-plastic wave, phase transition wave, and structural phase transformation wave. Additionally, temperature rise impedes atomic motion while lower strain rate promotes it, highlighting a competitive effect.
MECHANICS OF MATERIALS
(2022)
Article
Engineering, Civil
Byeong-Su Kim, Seong-Wan Park, Tara N. Lohani, Shoji Kato
Summary: This paper focuses on the theoretical representation of suction stress as an added confining pressure in evaluating the mechanical behavior of unsaturated soil under various confining pressure conditions. The concept of suction stress derived from triaxial compression test results was described, and its application in failure criteria analysis was discussed.
TRANSPORTATION GEOTECHNICS
(2022)
Article
Engineering, Mechanical
Prottay Malakar, Md Al Rifat Anan, Mahmudul Islam, Md Shajedul Hoque Thakur, Satyajit Mojumder
Summary: This paper studied the fracture and deformation mechanisms of functionally graded and coreshell Silver-Gold (Ag-Au) nanospheres under compression load using molecular dynamics simulation. The results showed that plastic deformation was influenced by dislocation nucleation and propagation, which varied with the alloying percentages of the nanospheres. An inverse size effect was observed for the mechanical properties and deformation mechanism.
INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES
(2022)
Article
Engineering, Environmental
Haifeng Huo, Biao Hu, Tao Li, Yajing Yang, Wentao Jia
Summary: This study simulated the natural snowfall process and obtained compacted snow samples through sintering at different temperatures. The results show that the failure of compacted snow bonds is mainly contributed by tension, and the ratio of tension and compression bond breaks increases with density. The normal contact force contributes more to the total axial stress.
COLD REGIONS SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Geological
S. H. Liu, B. X. Fang, Y. Lu, S. Chen
Summary: This study investigates the static bearing capacity and dynamic deformation behavior of stacked soilbags through a series of unconfined compression tests. The results show that the ultimate compressive strength and tangent compression modulus of soilbags tend to stabilize when the number of layers exceeds three. Under cyclic loading, the accumulated vertical strain of stacked soilbags increases nonlinearly but reduces with each loading cycle, eventually reaching a relatively stable state primarily characterized by elastic deformation. The resilient moduli of stacked soilbags slightly change during cyclic loading and increase with the increasing static vertical stress and decreasing cyclic load ratio. These findings demonstrate the feasibility of using soilbags as base isolation due to their high bearing capacity and stable deformation behavior under cyclic loading.
GEOSYNTHETICS INTERNATIONAL
(2023)
Article
Materials Science, Multidisciplinary
Xianglong Lin, Lilan Gao, Kai Li, Chunqiu Zhang, Ruixin Li, Yansong Tan, Xizheng Zhang
Summary: This study designed a silk fibroin/collagen type II scaffold and optimized the mechanical environment for the in vitro culture of chondrocytes. The results showed that the chondrocyte/scaffold complex could effectively improve cartilage repair after implantation. The study also provided a promising strategy for mechanical stimulation to promote functional in situ regeneration of articular cartilage.
MATERIALS & DESIGN
(2022)
Article
Orthopedics
Su-Jin Heo, Spencer E. Szczesny, Dong Hwa Kim, Kamiel S. Saleh, Robert L. Mauck
JOURNAL OF ORTHOPAEDIC RESEARCH
(2018)
Article
Orthopedics
Minwook Kim, Sean T. Garrity, David R. Steinberg, George R. Dodge, Robert L. Mauck
JOURNAL OF ORTHOPAEDIC RESEARCH
(2018)
Article
Engineering, Biomedical
Sarah E. Gullbrand, Dong Hwa Kim, Edward Bonnevie, Beth G. Ashinsky, Lachlan J. Smith, Dawn M. Elliott, Robert L. Mauck, Harvey E. Smith
ACTA BIOMATERIALIA
(2018)
Article
Rehabilitation
Zuozhen Tian, Xiaoyuan Ma, Miersalijiang Yasen, Robert L. Mauck, Ling Qin, Frances S. Shofer, Lachlan J. Smith, Maurizio Pacifici, Motomi Enomoto-Iwamoto, Yejia Zhang
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2018)
Article
Engineering, Mechanical
C. Han, J. -H. Lee, Y. S. Choi, S. -H. Park, S. Park
FATIGUE & FRACTURE OF ENGINEERING MATERIALS & STRUCTURES
(2018)
Article
Cell & Tissue Engineering
Farzad Yousefi, Minwook Kim, Syeda Yusra Nahri, Robert L. Mauck, Nancy Pleshko
TISSUE ENGINEERING PART A
(2018)
Article
Multidisciplinary Sciences
Feini Qu, Qing Li, Xiao Wang, Xuan Cao, Miltiadis H. Zgonis, John L. Esterhai, Vivek B. Shenoy, Lin Han, Robert L. Mauck
SCIENTIFIC REPORTS
(2018)
Article
Engineering, Biomedical
Mi Y. Kwon, Sebastian L. Vega, William M. Gramlich, Minwook Kim, Robert L. Mauck, Jason A. Burdick
ADVANCED HEALTHCARE MATERIALS
(2018)
Article
Chemistry, Multidisciplinary
Changwan Han, Inchul Sin, Hyerin Kwon, Seonghun Park
APPLIED SCIENCES-BASEL
(2018)
Article
Multidisciplinary Sciences
J. T. Martin, S. E. Gullbrand, D. H. Kim, K. Ikuta, C. G. Pfeifer, B. G. Ashinsky, L. J. Smith, D. M. Elliott, H. E. Smith, R. L. Mauck
SCIENTIFIC REPORTS
(2017)
Article
Thermodynamics
Changwan Han, Changhwan Yang, Hanjong Kim, Seonghun Park
ADVANCES IN MECHANICAL ENGINEERING
(2019)
Article
Materials Science, Multidisciplinary
Seulbi Lee, Hanjong Kim, Seonghun Park, Yoon Suk Choi
Summary: The study conducted fatigue tests on alloy 625 tubes brazed specimens and found that the variability in fatigue life is influenced by the presence of the brazed joint, as well as the spatial distribution of the grain size and carbides. The results showed that specimens exhibited different failure patterns at room temperature and 1000 K, with variations in fatigue life depending on the location of failure and sigma(max) values.
Article
Chemistry, Physical
Minhyeok Heo, Seonghun Park
Summary: This study obtained material properties of polyvinyl alcohol hydrogel (PVAH) that can reflect its mechanical behavior using finite element analysis and a biphasic continuum model, and also optimized the composition ratio of PVAH to replace the nucleus pulposus (NP) of the human intervertebral disc. Results showed that the mechanical properties of PVAH were similar to the NP at 15% and 20% weight percentages. Therefore, 20% PVAH is considered the most suitable material for replacing the NP.
Article
Multidisciplinary Sciences
Minhyeok Heo, Jihwan Yun, Hanjong Kim, Sang-Soo Lee, Seonghun Park
Summary: This study aimed to optimize a lumbar interspinous fixation device (LIFD) using a finite element model, allowing for minimally invasive surgery without compromising the normal behavior of the lumbar spine. The optimum number of spring turns and spring wire diameter were determined based on the dynamic range of motion (ROM) perspective. The optimized device was found to enhance stability and reduce the risk of degenerative diseases in adjacent lumbar segments.
Article
Engineering, Biomedical
Sarah E. Gullbrand, Thomas P. Schaer, Prateek Agarwal, Justin R. Bendigo, George R. Dodge, Weiliam Chen, Dawn M. Elliott, Robert L. Mauck, Neil R. Malhotra, Lachlan J. Smith
ACTA BIOMATERIALIA
(2017)