RNA sequencing identifies gene regulatory networks controlling extracellular matrix synthesis in intervertebral disk tissues

Cell therapy for the degenerating intervertebral disc

(2017) Wei Tong et al.   Translational Research

RNA-seq analysis of clinical-grade osteochondral allografts reveals activation of early response genes

(2016) Yang Lin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Pathogenesis and treatment of spine disease in the mucopolysaccharidoses

(2016) Sun H. Peck et al.   MOLECULAR GENETICS AND METABOLISM

Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production

(2016) Emily T. Camilleri et al.   Stem Cell Research & Therapy

Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2

(2015) Amel Dudakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining the phenotype of young healthy nucleus pulposus cells: Recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting

(2015) Makarand V. Risbud et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Theo Vos et al.   LANCET

Delayed hypertrophic differentiation of epiphyseal chondrocytes contributes to failed secondary ossification in mucopolysaccharidosis VII dogs

(2015) Sun H. Peck et al.   MOLECULAR GENETICS AND METABOLISM

The global burden of occupationally related low back pain: estimates from the Global Burden of Disease 2010 study

(2014) T Driscoll et al.   ANNALS OF THE RHEUMATIC DISEASES

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing

(2014) Krishna R Kalari et al.   BMC BIOINFORMATICS

MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal stem cells

(2014) Alfonso Eirin et al.   GENE

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Stem Cell Regeneration of Degenerated Intervertebral Discs: Current Status (Update)

(2013) Hamish T. J. Gilbert et al.   Current Pain and Headache Reports

Gene expression profile analysis of human intervertebral disc degeneration

(2013) Kai Chen et al.   GENETICS AND MOLECULAR BIOLOGY

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies

(2013) Lucas A Smolders et al.   ARTHRITIS RESEARCH & THERAPY

Microarray analysis of genes and gene functions in disc degeneration

(2013) YANCHUN TANG et al.   Experimental and Therapeutic Medicine

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Quantitative Proteomic Analysis of Eight Cartilaginous Tissues Reveals Characteristic Differences as well as Similarities between Subgroups

(2012) Patrik Önnerfjord et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of cell surface-specific markers to target human nucleus pulposus cells: Expression of carbonic anhydrase XII varies with age and degeneration

(2011) Karen A. Power et al.   ARTHRITIS AND RHEUMATISM

Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: Role of hypoxia-inducible factor proteins

(2011) Shilpa S. Gogate et al.   ARTHRITIS AND RHEUMATISM

Morphology of the human vertebral endplate

(2011) Azucena G. Rodriguez et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation

(2010) Ben M. Minogue et al.   ARTHRITIS AND RHEUMATISM

Degeneration and regeneration of the intervertebral disc: lessons from development

(2010) L. J. Smith et al.   Disease Models & Mechanisms

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers

(2010) Audrey Gilson et al.   ARTHRITIS RESEARCH & THERAPY

Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes

(2010) Ben M Minogue et al.   ARTHRITIS RESEARCH & THERAPY

Injury-induced sequential transformation of notochordal nucleus pulposus to chondrogenic and fibrocartilaginous phenotype in the mouse

(2009) Fan Yang et al.   JOURNAL OF PATHOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Differential Phenotype of Intervertebral Disc Cells

(2009) Daisuke Sakai et al.   SPINE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc

(2008) Amit Agrawal et al.   ARTHRITIS AND RHEUMATISM

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS