Article
Green & Sustainable Science & Technology
Hua-Chen Wu, Young-Kwon Park, Jia-Yin Lin, Bui Xuan Thanh, Attasak Jaree, Wei-Hsin Chen, Chia-Hua Lin, Siming You, Kun-Yi Andrew Lin
Summary: This study proposes activated carbon fiber (ACF) as a highly effective catalyst for the conversion of vanillic alcohol (VLA) to vanillic aldehyde (VAE) without using metals and oxidizing agents. The results show that reactive oxygen species derived from ACF-mediated aerobic reactions are responsible for the oxidation of VLA to VAE.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Environmental Sciences
Jie Zhao, Yu Wang, Huihui Liu, Yanlin Wu, Wenbo Dong
Summary: This study investigated the Fenton-like oxidation in a mixed system containing SA and VA in atmospheric aqueous, revealing that the addition of SA increased the HO center· yield and accelerated the oxidation of VA, potentially altering the mass ratio of SA and VA.
Article
Pharmacology & Pharmacy
Neha Sharma, Navneet Khurana, Arunachalam Muthuraman, Puneet Utreja
Summary: In this study, it was found that vanillic acid has anti-Parkinson's effects in rats induced with rotenone, reducing muscle rigidity and motor defects while lowering oxidative stress levels and providing neuroprotection for neurons.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Jana Klein, Robin Kupec, Markus Stoeckl, Siegfried R. Waldvogel
Summary: A new method using electrochemically generated ferrate is presented for the degradation of lignin and lignosulfonate. The method exclusively produces vanillic acid, which used to be considered a by-product. Lignin, as a natural resource, can replace fossil-based chemicals to reduce greenhouse gas emissions and positively impact climate change. By optimizing the reaction parameters, a yield of 7.2% of vanillic acid as a flavoring agent and antioxidant is achieved from a highly abundant bio-based side-stream on a laboratory scale.
ADVANCED SUSTAINABLE SYSTEMS
(2023)
Article
Agricultural Engineering
Fei Wang, Baojie Liu, Wenqing Cao, Lu Liu, Fanyan Zeng, Chengrong Qin, Chen Liang, Caoxing Huang, Shuangquan Yao
Summary: Aromatic acids are used selectively in the separation of hemicellulose, while phenolic acids inhibit lignin condensation. The current study utilizes vanillic acid (VA), which combines the characteristics of aromatic and phenolic acids, for the separation of eucalyptus. Under specific conditions (170°C, 8.0% VA concentration, and 80 min), efficient and selective separation of hemicellulose is achieved. Compared to acetic acid pretreatment, the yield of xylose increased from 78.80% to 88.59% and the yield of lignin decreased from 19.32% to 11.19%. In addition, there was an increase in the β-O-4 content of lignin by 5.78% after pretreatment. This study provides a new starting point for the development of efficient and sustainable commercial technology through organic acid pretreatment.
BIORESOURCE TECHNOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Li-Gong Zou, Yi-Tong Yao, Fu-Fang Wen, Xiao Zhang, Bo-Tao Liu, Da-Wei Li, Yu-Feng Yang, Wei-Dong Yang, Srinivasan Balamurugan, Hong-Ye Li
Summary: The excessive accumulation of catechol in the environment due to its burgeoning commercial applications poses a severe ecological threat. This study investigated the potential of the microalga Crypthecodinium cohnii to degrade catechol and utilize the byproduct as a carbon source. Results showed that catechol significantly increased the growth of C. cohnii and was rapidly catabolized within 60 hours. Transcriptomic analysis identified key genes involved in catechol degradation, and real-time polymerase chain reaction (RT-PCR) analysis revealed a remarkable increase in the transcription of these genes. The study also demonstrated altered primary metabolite content and the ability of C. cohnii to tolerate catechol treatment without adverse effects.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yu Huang, Jiarui Chen, Jin Lin, Jianhua Lin, Xuanwei Chen
Summary: VA@Au-MSN nanoparticles were designed for chemo-photothermal synergistic therapy of orthopedic infections, demonstrating excellent antibacterial activity against Staphylococcus aureus without cytotoxicity to bone cells. The unique properties of the nanoparticles allowed for controlled release of vanillic acid at the site of infection, providing a promising approach for the treatment of orthopedic infections.
Article
Biochemistry & Molecular Biology
Savita D. Girawale, Surya N. Meena, Vinod S. Nandre, Suresh B. Waghmode, Kisan M. Kodam
Summary: This study successfully achieved highly pure synthesis of vanillic acid from vanillin using whole cells of Ochrobactrum anthropi strain T5_1, and further validated the anti-tyrosinase and cytotoxic properties of vanillic acid on B16F1 skin cell line. The study also revealed the possible mechanism underlying the cell toxicity of vanillic acid.
BIOORGANIC & MEDICINAL CHEMISTRY
(2022)
Article
Biotechnology & Applied Microbiology
Rosa Margesin, Georg Volgger, Andreas O. Wagner, Dechao Zhang, Caroline Poyntner
Summary: This study found that Paraburkholderia aromaticivorans AR20-38 is capable of degrading lignin monomers at low and moderate temperatures, with the degradation of ferulic acid resulting in the stable production of high amounts of vanillic acid.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Ifedolapo M. Oke, Limpho M. Ramorobi, Samson S. Mashele, Susanna L. Bonnet, Tshepiso J. Makhafola, Kenneth C. Eze, Anwar E. M. Noreljaleel, Chika Chukwuma
Summary: The study synthesized a new Zn-vanillic acid complex with enhanced antioxidative and antihyperglycaemic properties compared to vanillic acid alone. The complex demonstrated significant bioactivity in cell-based and ex vivo models.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2021)
Article
Food Science & Technology
Jaskiran Kaur, Monica Gulati, Sachin Kumar Singh, Gowthamarajan Kuppusamy, Bhupinder Kapoor, Vijay Mishra, Saurabh Gupta, Mohammed F. Arshad, Omji Porwal, Niraj Kumar Jha, M. V. N. L. Chaitanya, Dinesh Kumar Chellappan, Gaurav Gupta, Piyush Kumar Gupta, Kamal Dua, Rubiya Khursheed, Ankit Awasthi, Leander Corrie
Summary: Vanillic acid exhibits diverse therapeutic effects against cancer, diabetes, obesity, neurodegenerative, cardiovascular, and hepatic diseases. Its derivatives also show potential in treating autoimmune diseases and fungal/bacterial infections. However, its limited oral bioavailability due to rapid metabolism hampers its delivery via conventional formulations. Efforts are required to develop nanoformulations of vanillic acid to overcome these challenges.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Nutrition & Dietetics
Marwa El-Sheikh, Ayman Mesalam, Myeong-Don Joo, Tabinda Sidrat, Ahmed Atef Mesalam, Il-Keun Kong
Summary: This study investigates the biological effects of vanillic acid on early embryo development. The results demonstrate that the supplementation of vanillic acid improves blastocyst development, reduces oxidative stress, promotes fatty acid oxidation, and enhances mitochondrial activity. It also suggests a potential link between vanillic acid and the AKT signaling pathway, indicating its potential application in assisted reproductive technologies to improve human fertility.
Article
Chemistry, Multidisciplinary
Neda Mirikaram, Alvaro Perez-Molina, Sergio Morales-Torres, Amir Salemi, Francisco J. Maldonado-Hodar, Luisa M. Pastrana-Martinez
Summary: ZnO-GO composites prepared by mixing GO with ZnO exhibit enhanced photocatalytic activity in degrading vanillic acid, with the composite containing 5.5 wt.% GO showing the highest efficiency. The presence of GO reduces photocorrosion and improves the stability of the composites during reuse experiments.
Article
Pharmacology & Pharmacy
Shaimaa S. Ibrahim, Hend Abd-Allah
Summary: This study aimed to enhance the delivery of vanillic acid (VA) for the treatment of ocular inflammation using novel surfactant-based elastic vesicular nanocarriers called Spanlastics. The formulation composed of Span 60 and Tween 80 displayed the smallest particle size and good physical stability. In vivo experiments showed that the VA-loaded Spanlastic formulation significantly reduced inflammation compared to the drug suspension.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Biochemistry & Molecular Biology
Eman S. Alamri, Haddad A. El Rabey, Othman R. Alzahrani, Fahad M. Almutairi, Eman S. Attia, Hala M. Bayomy, Renad A. Albalwi, Samar M. Rezk
Summary: This study investigated the hepatoprotective activity of vanillic acid, silymarin, and vanillic acid-loaded silver nanoparticles (AgNPs) against CCl4-induced hepatotoxicity in male rats. The results showed that treatment with vanillic acid-AgNPs and silymarin effectively protected the rats against CCl4-induced liver toxicity.
Article
Chemistry, Analytical
Jing-yan Kang, Yu-jie Zhang, Xing Li, Chen Dong, Hong-yu Liu, Li-jing Miao, Paul J. Low, Zhi-xian Gao, Narayan S. Hosmane, Ai-guo Wu
ANALYTICAL METHODS
(2018)
Article
Chemistry, Multidisciplinary
Xinmei Zhao, Leyong Zeng, Narayan Hosmane, Yan Gong, Aiguo Wu
CHINESE CHEMICAL LETTERS
(2019)
Review
Chemistry, Inorganic & Nuclear
Yinghuai Zhu, Shanmin Gao, Narayan S. Hosmane
INORGANICA CHIMICA ACTA
(2018)
Article
Materials Science, Biomaterials
Okan Icten, Dursun Ali Kose, Stephan J. Matissek, Jason A. Misurelli, Sherine F. Elsawa, Narayan S. Hosmane, Birgul Zumreoglu-Karan
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2018)
Article
Chemistry, Multidisciplinary
Yinghuai Zhu, Narayan S. Hosmane
PURE AND APPLIED CHEMISTRY
(2018)
Article
Biochemistry & Molecular Biology
Yinghuai Zhu, Yongxiang Lin, Narayan S. Hosmane
BIOORGANIC CHEMISTRY
(2019)
Article
Chemistry, Medicinal
Marlon R. Lutz, Sebastian Flieger, Andre Colorina, John Wozny, Narayan S. Hosmane, Daniel P. Becker
Article
Chemistry, Multidisciplinary
Yinghuai Zhu, Parichat Prommana, Narayan S. Hosmane, Paolo Coghi, Chairat Uthaipibull, Yingjun Zhang
Summary: Boron nanoparticles with hydroxyl groups were synthesized in situ and characterized using various analytical techniques. These nanoparticles exhibited good antimalarial activity against Plasmodium falciparum, while showing low toxicity to various cell lines.
Review
Biochemistry & Molecular Biology
Bhaskar C. Das, Nitesh K. Nandwana, Sasmita Das, Varsha Nandwana, Mohammed Adil Shareef, Yogarupa Das, Mariko Saito, Louis M. Weiss, Frankis Almaguel, Narayan S. Hosmane, Todd Evans
Summary: This review introduces current boron-containing drug candidates, including boron-based compounds for the treatment of different diseases. It also describes their synthesis, structure-activity relationship, and associated biological activities.
Article
Biochemistry & Molecular Biology
Martha L. Jimenez-Gonzalez, Juan Pablo F. Rebolledo-Chavez, Marisela Cruz-Ramirez, Rene Antano, Angel Mendoza, Narayan S. Hosmane, Lena Ruiz-Azuara, Jose Luis Hernandez-Lopez, Luis Ortiz-Frade
Summary: In this work, an electrochemical study of the Boron cage monomercaptoundecahydro-closo-dodecaborate [B12H11SH](2-) in solution and in a self-assembled monolayer over a gold electrode was conducted. The study revealed the interaction between the boron cage and the gold surface, formation of a self-assembled monolayer, and the reduction of active sites on the gold surface due to the presence of the boron cage. Bulkier thiols were found to enhance charge accumulation at the electrode-solution interface.
Review
Biochemistry & Molecular Biology
Varsha Nandwana, Nitesh K. Nandwana, Yogarupa Das, Mariko Saito, Tanisha Panda, Sasmita Das, Frankis Almaguel, Narayan S. Hosmane, Bhaskar C. Das
Summary: This review article summarizes the importance of gut microbiota in neurodevelopment and neurodegenerative disorders and discusses breakthroughs in using probiotics, prebiotics, and synbiotics for treating neurological illnesses. It also explores the role of a boron-based diet in memory and neurodegenerative diseases.
Article
Biochemistry & Molecular Biology
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R. Lutz, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham Moran, Prakasha Kempaiah, Narayan Hosmane, Minoru Suzuki, Daniel P. Becker
Summary: New carborane-bearing hydroxamate matrix metalloproteinase (MMP) ligands with nanomolar potency against MMP-2, -9 and -13 have been synthesized for boron neutron capture therapy (BNCT). In vitro studies showed that these new MMP ligands had high tumoricidal effects in the BNCT assay. This study highlights the importance of targeting MMP enzymes overexpressed on the surface of tumor cells for BNCT efficacy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Yinghuai Zhu, Jianghong Cai, Narayan S. Hosmane, Minoru Suzuki, Kazuko Uno, Yingjun Zhang, Mao Takagaki
Summary: Carboxyboranylamino ethanol was prepared with a 75.0% yield through an amine-exchange reaction. It showed lower cytotoxicity and higher anti-tumor efficacy in vitro compared to 4-borono-l-phenylalanine (BPA) and methyl 2-hydroxyl-5-(1'-ortho-carbonylmethyl-1',2',3'-triazol-4'-yl)-benzonate (2). The bio-enhancement was explained using molecular docking calculations.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Hongyu Liu, Zhuangwei Zhou, Yujie Zhang, Ningyi Chen, Jingyan Kang, Guijian Liu, Narayan S. Hosmane, Aiguo Wu
NANOSCALE ADVANCES
(2019)
Article
Chemistry, Inorganic & Nuclear
Guojun Hu, Ziyue Deng, Yanwei Wang, Dan Yuan, Yong Zhang, Yingming Yao
Summary: A series of rare-earth metal complexes were synthesized and used as efficient initiators for the polymerization of trimethylene carbonate (TMC) and (L)-lactide ((L)-LA).
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Van Ha Nguyen, John H. K. Yip
Summary: In this study, eight PtII-azulene complexes were synthesized to investigate the effect of metalation on the electronic structures, spectroscopy, and luminescence of organic chromophores. The results showed that the attachment of Pt substituents to azulene affected the HOMOs, LUMOs, and luminescence properties. The study provides insights into the role of metalation in modifying the properties of organic chromophores.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Moon Kedia, Virender Singh, Bhaskaran Shankar, Malaichamy Sathiyendiran
Summary: This study synthesized two types of neutral binuclear metallocycles using a one-pot solvothermal method and characterized their structures. The analysis revealed that these complexes adopt a binuclear heteroleptic cyclic architecture and belong to phosphine oxide donor (P=O)-based supramolecular coordination cyclic complexes.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Radhey S. Srivastava
Summary: This study demonstrates the effectiveness of zero-valent elements as reductants for the deoxydehydration reaction of polyols catalyzed by ONO-pincer ligated molybdenum dioxo. The insolubility and easy separability of the reductants and their oxidized products during the reaction are emphasized. Additionally, the choice of ligand has an impact on the catalytic performance of the reaction.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Hao Zhou, Yajun Sun, Li Deng, Weiran Yang, Yuehui Li
Summary: Efficient Ru-catalyzed hydrogenation of aldehydes was achieved using carbazole-derived phosphine ligands, with the crucial role of N-H moiety in promoting the catalytic reaction. The method was successfully applied in the Co/Ru-catalyzed hydroformylation process, resulting in the production of long-chain alcohols with excellent yields.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Theodor Danescu, Alexandru Lupan, Radu Silaghi-Dumitrescu, R. Bruce King
Summary: The structures and energies of complexes containing (Me2C2N2P)2Ru2(CO)n and (Me2C2N2P)2Fe2(CO)n have been studied. Low-energy structures are characterized by the presence of bridging diazaphospholyl rings, while higher-energy structures involve different ligand structures.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Savannah C. Kapper, Aamani Ponnekanti, Jonas Schaab, Tian-yi Li, Christine L. Chung, Gael Ung, Peter I. Djurovich, Mark E. Thompson
Summary: Organometallic iridium complexes with two cyclometalated ligands and one bis-oxazoline derived ancillary ligand were studied. These complexes have emission spanning across the visible and near-ultraviolet region, with moderate to high photoluminescence quantum yields. The (ppy)2Ir(BOX-CN) complexes were resolved into Delta- and Lambda-diastereomers based on solubility differences.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Zahra Karimi Sangari, Hossein Naeimi
Summary: In this research, a nanostructured CoCuFe2O4 catalyst was prepared using a brief and useful synthetic strategy. This catalyst was used for synthesizing 1,2,4,5-tetrasubstituted imidazole derivatives under ultrasonic irradiation. The approach offers advantages such as high efficiency, short reaction times, simplicity of the reaction medium, accelerated reaction rates, and easier separation and purification of products.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Rukhsana Gul, Wajid Munir, Ebraheem Abdu Musad Saleh, Shaukat Shujah, Muhammad Sirajuddin, Saira Tabassum, Khalil Ur Rehman, Dilfaraz Khan, Sameerah I. Al-Saeedi, Ehab A. Abdelrahman
Summary: Two new Schiff base ligands were synthesized and used to form copper, nickel, and cobalt complexes. The synthesized compounds were characterized and screened for various biological activities. The metal complexes showed better activities in antibacterial, antifungal, antidiabetic, and antioxidant assays.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Review
Chemistry, Inorganic & Nuclear
Ahsan Nazir, Pengwei Huo, Ameena Tur Rasool
Summary: This review explores the potential of g-C3N4-based S-scheme heterojunctions in addressing environmental issues. It summarizes the mechanism and preparation techniques of S-scheme heterojunctions based on g-C3N4, and presents recent studies on their applications in pollutant removal, CO2 reduction, hydrogen production, and bacterial disinfection. The review concludes with an outlook on future challenges for g-C3N4-based S-scheme heterojunctions.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Francois Mazars, Koffi Senam Etse, Guillermo Zaragoza, Lionel Delaude
Summary: The activity of three Pd-PEPPSI catalyst precursors with N-heterocyclic carbene (NHC) ligands derived from caffeine and theophylline in Mizoroki-Heck reactions was tested. The results showed that the catalysts achieved high conversions and yields, especially in the presence of electron-withdrawing substituents.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Bo-Han Wu, Xue Zhou, Lin Liu, Zheng-Bo Han
Summary: Researching carbon dioxide removal from flue gas and natural gas is crucial. Metal-organic frameworks (MOFs) are commonly used in adsorption due to their high surface area, porosity, and chemical properties. An ultra-microporous MOF CPM-20(Co) with mixed ligand was synthesized using inexpensive ligands. The material exhibited high selectivities and low regenerative energy, making it a promising option for CO2 separation in industries.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2024)