Beta-adrenergic receptor agonist decreases VEGF levels through altered eNOS and PKC signaling in diabetic retina

What have we learnt about the management of diabetic macular edema in the antivascular endothelial growth factor and corticosteroid era?

(2015) Aniruddha Agarwal et al.   CURRENT OPINION IN OPHTHALMOLOGY

Suppression of protein kinase C-ζ attenuates vascular leakage via prevention of tight junction protein decrease in diabetic retinopathy

(2014) Hyun Beom Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

β-adrenergic receptor antagonists inhibit vasculogenesis of embryonic stem cells by downregulation of nitric oxide generation and interference with VEGF signalling

(2014) Fatemeh Sharifpanah et al.   CELL AND TISSUE RESEARCH

New treatments for diabetic retinopathy

(2014) A. Das et al.   DIABETES OBESITY & METABOLISM

Protective Effects of  1/2 Adrenergic Receptor Deletion in a Model of Oxygen-Induced Retinopathy

(2014) M. Dal Monte et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

β-Blockers Promote Angiogenesis in the Mouse Aortic Ring Assay

(2014) Tonino Stati et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

IGFBP-3 inhibits TNF-α production and TNFR-2 signaling to protect against Retinal Endothelial Cell Apoptosis

(2014) Qiuhua Zhang et al.   MICROVASCULAR RESEARCH

Beta3-adrenergic receptors modulate vascular endothelial growth factor release in response to hypoxia through the nitric oxide pathway in mouse retinal explants

(2013) Massimo Dal Monte et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

β2-Adrenergic Receptor Knockout Mice Exhibit A Diabetic Retinopathy Phenotype

(2013) Youde Jiang et al.   PLoS One

PKCζ Mediates Breakdown of Outer Blood-Retinal Barriers in Diabetic Retinopathy

(2013) Samy Omri et al.   PLoS One

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives

(2013) Rafael Simó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood–retinal barrier dysfunction

(2012) Paul M. Titchenell et al.   BIOCHEMICAL JOURNAL

Dehydroepiandrosterone Prevents the Aggregation of Platelets Obtained from Postmenopausal Women with Type 2 Diabetes Mellitus through the Activation of the PKC/eNOS/NO Pathway

(2012) Y. Muñoz et al.   HORMONE AND METABOLIC RESEARCH

Protection of Blood Retinal Barrier and Systemic Vasculature by Insulin-Like Growth Factor Binding Protein-3

(2012) Yagna P. R. Jarajapu et al.   PLoS One

Microglia/Macrophages Migrate through Retinal Epithelium Barrier by a Transcellular Route in Diabetic Retinopathy

(2011) Samy Omri et al.   AMERICAN JOURNAL OF PATHOLOGY

Alterations to the Blood–Retinal Barrier in Diabetes: Cytokines and Reactive Oxygen Species

(2011) Tiffany Frey et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of endothelial nitric oxide synthase (eNOS) in chronic stress-promoted tumour growth

(2011) Antonio Barbieri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

RANDOMIZED TRIAL EVALUATING SHORT-TERM EFFECTS OF INTRAVITREAL RANIBIZUMAB OR TRIAMCINOLONE ACETONIDE ON MACULAR EDEMA AFTER FOCAL/GRID LASER FOR DIABETIC MACULAR EDEMA IN EYES ALSO RECEIVING PANRETINAL PHOTOCOAGULATION

(2011) Joseph Googe et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Inhibition of Protein Kinase C δ Attenuates Blood-Retinal Barrier Breakdown in Diabetic Retinopathy

(2010) Jeong-Hun Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

Translocation of protein kinase C isoforms is involved in propofol-induced endothelial nitric oxide synthase activation

(2010) L. Wang et al.   BRITISH JOURNAL OF ANAESTHESIA

Activation of Protein Kinase C Isoforms and Its Impact on Diabetic Complications

(2010) Pedro Geraldes et al.   CIRCULATION RESEARCH

TNF-  Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

(2010) C. A. Aveleira et al.   DIABETES

Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1α protein-dependent mechanism

(2010) Soon Young Park et al.   INTERNATIONAL JOURNAL OF CANCER

Insulin-Like Growth Factor Binding Protein-3 Mediates Vascular Repair by Enhancing Nitric Oxide Generation

(2009) Jennifer L. Kielczewski et al.   CIRCULATION RESEARCH