Protection of Blood Retinal Barrier and Systemic Vasculature by Insulin-Like Growth Factor Binding Protein-3

Novel Protective Properties of IGFBP-3 Result in Enhanced Pericyte Ensheathment, Reduced Microglial Activation, Increased Microglial Apoptosis, and Neuronal Protection after Ischemic Retinal Injury

(2011) Jennifer L. Kielczewski et al.   AMERICAN JOURNAL OF PATHOLOGY

Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways

(2011) Rachid Kacimi et al.   Journal of Inflammation-London

Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Anti-tumor Effects in Breast and Prostate Cancer

(2010) Angela R. Ingermann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies

(2010)   LANCET ONCOLOGY

Increased nitric oxide synthase activity is essential for electromagnetic-pulse-induced blood–retinal barrier breakdown in vivo

(2009) Lianjun Lu et al.   BRAIN RESEARCH

Insulin-Like Growth Factor Binding Protein-3 Mediates Vascular Repair by Enhancing Nitric Oxide Generation

(2009) Jennifer L. Kielczewski et al.   CIRCULATION RESEARCH

Retinopathy of Prematurity: Current Concepts in Molecular Pathogenesis

(2009) Gena Heidary et al.   Seminars in Ophthalmology

IGFBPs contribute to survival of pancreatic cancer cells under severely hypoxic conditions

(2008) Takumi Koga et al.   CANCER LETTERS

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

(2008) Weidong Zhu et al.   NATURE