Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

Injury mechanisms in acute intracerebral hemorrhage

(2018) D. Andrew Wilkinson et al.   NEUROPHARMACOLOGY

Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats

(2018) Zhiyi Xie et al.   NEUROPHARMACOLOGY

Understanding melanocortin-4 receptor control of neuronal circuits: Toward novel therapeutics for obesity syndrome

(2018) Sang Hyeon Ju et al.   PHARMACOLOGICAL RESEARCH

Melanocortin 4 Receptor Activation Attenuates Mitochondrial Dysfunction in Skeletal Muscle of Diabetic Rats

(2017) Hao-Hao Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Endogenous hydrogen sulphide attenuates NLRP3 inflammasome-mediated neuroinflammation by suppressing the P2X7 receptor after intracerebral haemorrhage in rats

(2017) Hengli Zhao et al.   Journal of Neuroinflammation

Metformin Attenuates Neurological Deficit after Intracerebral Hemorrhage by Inhibiting Apoptosis, Oxidative Stress and Neuroinflammation in Rats

(2017) Boxiang Qi et al.   NEUROCHEMICAL RESEARCH

Multiple beneficial effects of melanocortin MC4 receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectives

(2017) Daniela Giuliani et al.   PROGRESS IN NEUROBIOLOGY

Platelet-Derived Growth Factor Receptor-β Regulates Vascular Smooth Muscle Cell Phenotypic Transformation and Neuroinflammation After Intracerebral Hemorrhage in Mice

(2016) Peng Yang et al.   CRITICAL CARE MEDICINE

Recombinant Gas6 augments Axl and facilitates immune restoration in an intracerebral hemorrhage mouse model

(2016) Lu-sha Tong et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Upregulation of hepatic melanocortin 4 receptor during rat liver regeneration

(2016) Min Xu et al.   JOURNAL OF SURGICAL RESEARCH

Microglial Polarization and Inflammatory Mediators After Intracerebral Hemorrhage

(2016) Zhen Zhang et al.   MOLECULAR NEUROBIOLOGY

Role of the AMPK signaling pathway in early brain injury after subarachnoid hemorrhage in rats

(2015) Ji-Yang An et al.   ACTA NEUROCHIRURGICA

Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus

(2015) D. Ramírez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage

(2015) Loretta O. Iniaghe et al.   NEUROBIOLOGY OF DISEASE

Melanocortin MC4 receptor agonists alleviate brain damage in abdominal compartment syndrome in the rat

(2015) Dong Liu et al.   NEUROPEPTIDES

Activation of Dopamine D2 Receptor Suppresses Neuroinflammation Through αB-Crystalline by Inhibition of NF-κB Nuclear Translocation in Experimental ICH Mice Model

(2015) Yang Zhang et al.   STROKE

Antithrombin up-regulates AMP-activated protein kinase signalling during myocardial ischaemia/reperfusion injury

(2015) Yina Ma et al.   THROMBOSIS AND HAEMOSTASIS

Neuroimaging in Intracerebral Hemorrhage

(2014) Federica Macellari et al.   STROKE

An Update on Inflammation in the Acute Phase of Intracerebral Hemorrhage

(2014) Sheng Chen et al.   Translational Stroke Research

ACTH protects mature oligodendroglia from excitotoxic and inflammation-related damagein vitro

(2013) Joyce A. Benjamins et al.   GLIA

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK

(2013) Sergey Filippov et al.   JOURNAL OF LIPID RESEARCH

Astrocytes: new targets of melanocortin 4 receptor actions

(2013) Carla Caruso et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Melanocortin-4 Receptor Regulates Hippocampal Synaptic Plasticity through a Protein Kinase A-Dependent Mechanism

(2013) Y. Shen et al.   JOURNAL OF NEUROSCIENCE

Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation

(2013) Yu Zhou et al.   PROGRESS IN NEUROBIOLOGY

Hematology and Inflammatory Signaling of Intracerebral Hemorrhage

(2013) W. C. Ziai   STROKE

Molecular Changes Induced in Rat Liver by Hemorrhage and Effects of Melanocortin Treatment

(2012) Caterina Lonati et al.   ANESTHESIOLOGY

Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation

(2012) Ian P Salt et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Melanocortin 4 receptor stimulation decreases pancreatitis severity in rats by activation of the cholinergic anti-inflammatory pathway*

(2011) Letteria Minutoli et al.   CRITICAL CARE MEDICINE

Protective effects of melanocortins on short-term changes in a rat model of traumatic brain injury*

(2011) Alessandra Bitto et al.   CRITICAL CARE MEDICINE

Melanocortin MC4 receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia

(2011) Luca Spaccapelo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melanocortin receptors in rat liver cells: change of gene expression and intracellular localization during acute-phase response

(2011) Ihtzaz Ahmed Malik et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Activated Microglia Are Less Vulnerable to Hemin Toxicity due to Nitric Oxide-Dependent Inhibition of JNK and p38 MAPK Activation

(2011) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Melanocortins protect against multiple organ dysfunction syndrome in mice

(2010) Alessandra Bitto et al.   BRITISH JOURNAL OF PHARMACOLOGY

Advances in Neuroprotective Strategies: Potential Therapies for Intracerebral Hemorrhage

(2010) Brian Y. Hwang et al.   CEREBROVASCULAR DISEASES

Targeting the melanocortin receptor system for anti-stroke therapy

(2010) Paul M. Holloway et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Central AMPK contributes to sleep homeostasis in mice

(2009) Sachiko Chikahisa et al.   NEUROPHARMACOLOGY

Melanocortin-4 receptor activation inhibits c-Jun N-terminal kinase activity and promotes insulin signaling

(2009) Biaoxin Chai et al.   PEPTIDES

Activation of c-Jun-N-terminal kinase in a rat model of intracerebral hemorrhage: The role of iron

(2008) Shu Wan et al.   NEUROSCIENCE RESEARCH

Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage

(2007) D Giuliani et al.   BRITISH JOURNAL OF PHARMACOLOGY