Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?

HSP60 plays a regulatory role in IL-1β-induced microglial inflammation via TLR4-p38 MAPK axis

(2016) Shalini Swaroop et al.   Journal of Neuroinflammation

Tolerization against atherosclerosis using heat shock protein 60

(2015) Cecilia Wick   CELL STRESS & CHAPERONES

The Hsp60 peptide p277 enhances anti-CD3 mediated diabetes remission in non-obese diabetic mice

(2015) Ghanashyam Sarikonda et al.   JOURNAL OF AUTOIMMUNITY

Recent insights into the cellular biology of atherosclerosis

(2015) Ira Tabas et al.   JOURNAL OF CELL BIOLOGY

Autoimmune Aspects of Type 2 Diabetes Mellitus - A Mini-Review

(2014) Bianca K. Itariu et al.   GERONTOLOGY

Immune modulation in humans: implications for type 1 diabetes mellitus

(2014) Bart O. Roep et al.   Nature Reviews Endocrinology

Toll-Like Receptor Activation in Immunity vs. Tolerance in Autoimmune Diabetes

(2014) Elke Gülden et al.   Frontiers in Immunology

Danger Signals in the Initiation of the Inflammatory Response after Myocardial Infarction

(2013) J. J. de Haan et al.   MEDIATORS OF INFLAMMATION

Mitochondrial function and insulin secretion

(2013) Pierre Maechler   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hyperglycaemia and oxidative stress upregulate HSP60 & HSP70 expression in HeLa cells

(2013) Luke Hall et al.   SpringerPlus

Impact of Diabetes on Cardiovascular Disease: An Update

(2013) Alessandra Saldanha de Mattos Matheus et al.   International Journal of Hypertension

Signaling the mitochondrial unfolded protein response

(2012) Mark W. Pellegrino et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Recognition of heat shock protein 60 epitopes in children with type 1 diabetes

(2012) A. A. Verrijn Stuart et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Treatment of autoimmune diabetes in NOD mice by Toll-like receptor 2 tolerance in conjunction with dipeptidyl peptidase 4 inhibition

(2012) D.-H. Kim et al.   DIABETOLOGIA

The Past 200 Years in Diabetes

(2012) Kenneth S. Polonsky   NEW ENGLAND JOURNAL OF MEDICINE

Heat Shock Protein 60 and Immune Inflammatory Responses in Atherosclerosis

(2011) Cecilia Grundtman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Detection of Hsp60 in saliva and serum from type 2 diabetic and non-diabetic control subjects

(2011) Jing Yuan et al.   CELL STRESS & CHAPERONES

Immunological efficacy of heat shock protein 60 peptide DiaPep277TM therapy in clinical type I diabetes

(2010) V. A. L. Huurman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

(2010) M. R. Dasu et al.   DIABETES CARE

Hsp60 Is Actively Secreted by Human Tumor Cells

(2010) Anna M. Merendino et al.   PLoS One

The HSP60 immune system network

(2010) Francisco J. Quintana et al.   TRENDS IN IMMUNOLOGY

Toll-Like Receptors and Diabetes

(2009) F. Susan Wong et al.   Annals of the New York Academy of Sciences

Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants

(2009) Brian Henderson et al.   CELL STRESS & CHAPERONES

Toll-like receptor 4 and inducible nitric oxide synthase gene polymorphisms are associated with Type 2 diabetes

(2009) Renata A. Bagarolli et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Heat shock proteins and immune system

(2009) Min-Fu Tsan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects

(2008) S. M. Reyna et al.   DIABETES

Emerging role of Toll-like receptors in atherosclerosis

(2008) Linda K. Curtiss et al.   JOURNAL OF LIPID RESEARCH

HSP60 as a Target of Anti-Ergotypic Regulatory T Cells

(2008) Francisco J. Quintana et al.   PLoS One