Role of the indoleamine-2,3-dioxygenase/kynurenine pathway of tryptophan metabolism in behavioral alterations in a hepatic encephalopathy rat model

Oren-gedoku-to and its Constituents with Therapeutic Potential in Alzheimer's Disease Inhibit Indoleamine 2, 3-Dioxygenase Activity In Vitro

(2017) Cun-Jing Yu et al.   JOURNAL OF ALZHEIMERS DISEASE

Indoleamine-2,3-dioxygenase mediates neurobehavioral alterations induced by an intracerebroventricular injection of amyloid-β 1-42 peptide in mice

(2016) Leandro Cattelan Souza et al.   BRAIN BEHAVIOR AND IMMUNITY

Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice

(2016) Matthew McMillin et al.   Journal of Neuroinflammation

Reducing Peripheral Inflammation with Infliximab Reduces Neuroinflammation and Improves Cognition in Rats with Hepatic Encephalopathy

(2016) Sherry Dadsetan et al.   Frontiers in Molecular Neuroscience

Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory

(2015) Jillian M. Heisler et al.   BRAIN BEHAVIOR AND IMMUNITY

Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms

(2015) Vicente Hernandez-Rabaza et al.   Journal of Neuroinflammation

Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress

(2015) Ying Xu et al.   NEUROBIOLOGY OF AGING

Morphological changes of cortical pyramidal neurons in hepatic encephalopathy

(2014) Jeng-Rung Chen et al.   BMC NEUROSCIENCE

The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling

(2014) Yingcong Yu et al.   METABOLIC BRAIN DISEASE

Ingestion of Lactobacillus strain reduces anxiety and improves cognitive function in the hyperammonemia rat

(2014) Jia Luo et al.   Science China-Life Sciences

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease

(2013) Amos A. Fatokun et al.   AMINO ACIDS

Gene expression profiling in the cerebral cortex of patients with cirrhosis with and without hepatic encephalopathy

(2013) Boris Görg et al.   HEPATOLOGY

NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice

(2013) Adam K Walker et al.   NEUROPSYCHOPHARMACOLOGY

Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge

(2012) Alexander Salazar et al.   HORMONES AND BEHAVIOR

Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression

(2012) Hyangin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Antidepressant-like effect of trans-resveratrol in chronic stress model: Behavioral and neurochemical evidences

(2012) Yingcong Yu et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Impairment of the Organization of Locomotor and Exploratory Behaviors in Bile Duct-Ligated Rats

(2012) Renata Leke et al.   PLoS One

Effects of opioidergic systems upon anxiolytic-like behaviors induced in cholestatic rats

(2011) Delaram Eslimi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Opposing Biological Functions of Tryptophan Catabolizing Enzymes During Intracellular Infection

(2011) Senad Divanovic et al.   JOURNAL OF INFECTIOUS DISEASES

Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy

(2011) Vicente Felipo et al.   METABOLIC BRAIN DISEASE

New assessment of hepatic encephalopathy

(2010) Juan Córdoba   JOURNAL OF HEPATOLOGY

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

The interaction between high ammonia diet and bile duct ligation in developing rats: assessment by spatial memory and asymmetric dimethylarginine

(2009) Li-Tung Huang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

IL-6 and IL-18 in Blood May Discriminate Cirrhotic Patients With and Without Minimal Hepatic Encephalopathy

(2009) Carmina Montoliu et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior

(2009) J. C. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factor  Signaling during Peripheral Organ Inflammation

(2009) C. D'Mello et al.   JOURNAL OF NEUROSCIENCE

Experimental models of hepatic encephalopathy: ISHEN guidelines

(2009) Roger F. Butterworth et al.   LIVER INTERNATIONAL

Mammillary body alterations and spatial memory impairment in Wistar rats with thioacetamide-induced cirrhosis

(2008) Marta Méndez et al.   BRAIN RESEARCH

Pathogenetic mechanisms of hepatic encephalopathy

(2008) D Haussinger et al.   GUT

Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration

(2008) Caroline André et al.   JOURNAL OF NEUROIMMUNOLOGY

Glutamatergic and gabaergic neurotransmission and neuronal circuits in hepatic encephalopathy

(2008) Omar Cauli et al.   METABOLIC BRAIN DISEASE

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for IFN-γ?

(2008) Thomas J. Connor et al.   NEUROSCIENCE LETTERS

Minimal hepatic encephalopathy matters in daily life

(2008) Jasmohan S Bajaj   WORLD JOURNAL OF GASTROENTEROLOGY

Interleukin-1-induced interleukin-6 synthesis is mediated by the neutral sphingomyelinase/Src kinase pathway in neurones

(2007) N Tsakiri et al.   BRITISH JOURNAL OF PHARMACOLOGY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE