Gold Nanoparticles as X-Ray, CT, and Multimodal Imaging Contrast Agents: Formulation, Targeting, and Methodology

Evaluation of spectral photon counting computed tomography K-edge imaging for determination of gold nanoparticle biodistribution in vivo

(2017) Salim Si-Mohamed et al.   Nanoscale

A tumor-specific cleavable nanosystem of PEG-modified C60@Au hybrid aggregates for radio frequency-controlled release, hyperthermia, photodynamic therapy and X-ray imaging

(2016) Jinjin Shi et al.   Acta Biomaterialia

Comparative Effect of Contrast Media Type on the Incidence of Contrast-Induced Nephropathy

(2016) John Eng et al.   ANNALS OF INTERNAL MEDICINE

Labeling monocytes with gold nanoparticles to track their recruitment in atherosclerosis with computed tomography

(2016) Peter Chhour et al.   BIOMATERIALS

Tunable, biodegradable gold nanoparticles as contrast agents for computed tomography and photoacoustic imaging

(2016) Rabee Cheheltani et al.   BIOMATERIALS

Gentamicin-gold nanoparticles conjugate: a contrast agent for X-ray imaging of infectious foci due to Staphylococcus aureus

(2016) Azam Ahangari et al.   IET Nanobiotechnology

Theranostic Application of Mixed Gold and Superparamagnetic Iron Oxide Nanoparticle Micelles in Glioblastoma Multiforme

(2016) Lova Sun et al.   Journal of Biomedical Nanotechnology

Gold silver alloy nanoparticles (GSAN): an imaging probe for breast cancer screening with dual-energy mammography or computed tomography

(2016) Pratap C. Naha et al.   Nanoscale

Au/Polypyrrole@Fe3O4 Nanocomposites for MR/CT Dual-Modal Imaging Guided-Photothermal Therapy: An in Vitro Study

(2015) Wei Feng et al.   ACS Applied Materials & Interfaces

Marriage Strategy of Structure and Composition Designs for Intensifying Ultrasound & MR & CT Trimodal Contrast Imaging

(2015) Kun Zhang et al.   ACS Applied Materials & Interfaces

Radiofrequency-Triggered Tumor-Targeting Delivery System for Theranostics Application

(2015) Lei Wang et al.   ACS Applied Materials & Interfaces

Poly(acrylic acid) Bridged Gadolinium Metal–Organic Framework–Gold Nanoparticle Composites as Contrast Agents for Computed Tomography and Magnetic Resonance Bimodal Imaging

(2015) Chixia Tian et al.   ACS Applied Materials & Interfaces

Contrast-Enhanced X-ray Detection of Microcalcifications in Radiographically Dense Mammary Tissue Using Targeted Gold Nanoparticles

(2015) Lisa E. Cole et al.   ACS Nano

Nanomedicine for Cancer Immunotherapy: Tracking Cancer-Specific T-Cells in Vivo with Gold Nanoparticles and CT Imaging

(2015) Rinat Meir et al.   ACS Nano

Multifunctional Dendrimer-Entrapped Gold Nanoparticles Modified with RGD Peptide for Targeted Computed Tomography/Magnetic Resonance Dual-Modal Imaging of Tumors

(2015) Qian Chen et al.   ANALYTICAL CHEMISTRY

In vivo tumor-targeted dual-modal fluorescence/CT imaging using a nanoprobe co-loaded with an aggregation-induced emission dye and gold nanoparticles

(2015) Jimei Zhang et al.   BIOMATERIALS

Hyaluronic acid-modified Fe3O4@Au core/shell nanostars for multimodal imaging and photothermal therapy of tumors

(2015) Jingchao Li et al.   BIOMATERIALS

Synthesis and application of strawberry-like Fe 3 O 4 -Au nanoparticles as CT-MR dual-modality contrast agents in accurate detection of the progressive liver disease

(2015) Hui Y. Zhao et al.   BIOMATERIALS

Dendrimer-entrapped gold nanoparticles modified with RGD peptide and alpha-tocopheryl succinate enable targeted theranostics of cancer cells

(2015) Jingyi Zhu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Multifunctional hollow gold nanoparticles designed for triple combination therapy and CT imaging

(2015) Jaesook Park et al.   JOURNAL OF CONTROLLED RELEASE

The tumor-targeting core–shell structured DTX-loaded PLGA@Au nanoparticles for chemo-photothermal therapy and X-ray imaging

(2015) Yongwei Hao et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle Loaded Polymeric Microbubbles as Contrast Agents for Multimodal Imaging

(2015) Nutte Teraphongphom et al.   LANGMUIR

Strong Coupling between Plasmonic Gap Modes and Photonic Lattice Modes in DNA-Assembled Gold Nanocube Arrays

(2015) Qing-Yuan Lin et al.   NANO LETTERS

Gold nanoparticles as contrast agents in x-ray imaging and computed tomography

(2015) Lisa E Cole et al.   Nanomedicine

Intravenous Iodinated Contrast Agents Amplify DNA Radiation Damage at CT

(2015) Eike I. Piechowiak et al.   RADIOLOGY

Facile and Scalable Synthesis of Novel Spherical Au Nanocluster Assemblies@Polyacrylic Acid/Calcium Phosphate Nanoparticles for Dual-Modal Imaging-Guided Cancer Chemotherapy

(2015) Lu Li et al.   Small

Dendrimer-Assisted Formation of Fe3O4/Au Nanocomposite Particles for Targeted Dual Mode CT/MR Imaging of Tumors

(2015) Hongdong Cai et al.   Small

Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles

(2015) Jeong-Yeon Kim et al.   Theranostics

Vulnerable Plaque Detection and Quantification with Gold Particle–Enhanced Computed Tomography in Atherosclerotic Mouse Models

(2015) David De Wilde et al.   Molecular Imaging

Fluorescence-Guided Probes of Aptamer-Targeted Gold Nanoparticles with Computed Tomography Imaging Accesses for in Vivo Tumor Resection

(2015) Cheng-Hung Li et al.   Scientific Reports

Synthesis and Characterization of PEGylated Polyethylenimine-Entrapped Gold Nanoparticles for Blood Pool and Tumor CT Imaging

(2014) Benqing Zhou et al.   ACS Applied Materials & Interfaces

Lipid-AuNPs@PDA Nanohybrid for MRI/CT Imaging and Photothermal Therapy of Hepatocellular Carcinoma

(2014) Yongyi Zeng et al.   ACS Applied Materials & Interfaces

Lactobionic Acid-Modified Dendrimer-Entrapped Gold Nanoparticles for Targeted Computed Tomography Imaging of Human Hepatocellular Carcinoma

(2014) Hui Liu et al.   ACS Applied Materials & Interfaces

Selective Uptake and Imaging of Aptamer- and Antibody-Conjugated Hollow Nanospheres Targeted to Epidermal Growth Factor Receptors Overexpressed in Head and Neck Cancer

(2014) Marites Pasuelo Melancon et al.   ACS Nano

Label-Free Au Cluster Used for in Vivo 2D and 3D Computed Tomography of Murine Kidneys

(2014) Yaling Wang et al.   ANALYTICAL CHEMISTRY

Superparamagnetic iron oxide nanoparticles exacerbate the risks of reactive oxygen species-mediated external stresses

(2014) Cheng Luo et al.   ARCHIVES OF TOXICOLOGY

Prussian blue coated gold nanoparticles for simultaneous photoacoustic/CT bimodal imaging and photothermal ablation of cancer

(2014) Lijia Jing et al.   BIOMATERIALS

Silica-Encapsulated Gd3+-Aggregated Gold Nanoclusters for In Vitro and In Vivo Multimodal Cancer Imaging

(2014) Xiaotong Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enhancing multimodality functional and molecular imaging using glucose-coated gold nanoparticles

(2014) G. Feng et al.   CLINICAL RADIOLOGY

Contrast Agents for Photoacoustic and Thermoacoustic Imaging: A Review

(2014) Dan Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Noninvasive detection of macrophages in atherosclerotic lesions by computed tomography enhanced with PEGylated gold nanoparticles

(2014) Xin-Wu Lu et al.   International Journal of Nanomedicine

Applications of Gold Nanoparticles in Optical Biosensors

(2014) Libo Nie et al.   Journal of Biomedical Nanotechnology

Lectin-Conjugated Fe2O3@Au Core@Shell Nanoparticles as Dual Mode Contrast Agents for in Vivo Detection of Tumor

(2014) Xiuxia He et al.   MOLECULAR PHARMACEUTICS

Gold Nanoparticles for Nucleic Acid Delivery

(2014) Ya Ding et al.   MOLECULAR THERAPY

Gold nanoparticle-mediated photothermal therapy: current status and future perspective

(2014) Sekyu Hwang et al.   Nanomedicine

Synthesis of PEGylated low generation dendrimer-entrapped gold nanoparticles for CT imaging applications

(2014) Hui Liu et al.   Nanoscale

Dual-Energy Micro-CT Functional Imaging of Primary Lung Cancer in Mice Using Gold and Iodine Nanoparticle Contrast Agents: A Validation Study

(2014) Jeffrey R. Ashton et al.   PLoS One

Magneto-Plasmonic Au-Fe Alloy Nanoparticles Designed for Multimodal SERS-MRI-CT Imaging

(2014) Vincenzo Amendola et al.   Small

Gold Nanoshelled Liquid Perfluorocarbon Nanocapsules for Combined Dual Modal Ultrasound/CT Imaging and Photothermal Therapy of Cancer

(2014) Hengte Ke et al.   Small

Application of gold nanoparticles in biomedical and drug delivery

(2014) Hadis Daraee et al.   Artificial Cells Nanomedicine and Biotechnology

Facile One-Pot Synthesis of Fe3O4@Au Composite Nanoparticles for Dual-Mode MR/CT Imaging Applications

(2013) Jingchao Li et al.   ACS Applied Materials & Interfaces

Encapsulation of Particle Ensembles in Graphene Nanosacks as a New Route to Multifunctional Materials

(2013) Yantao Chen et al.   ACS Nano

Gold Nanocrystal Labeling Allows Low-Density Lipoprotein Imaging from the Subcellular to Macroscopic Level

(2013) Iris E. Allijn et al.   ACS Nano

Gold Nanoparticles Provide Bright Long-Lasting Vascular Contrast for CT Imaging

(2013) Joyce T. Au et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Facile formation of folic acid-modified dendrimer-stabilized gold–silver alloy nanoparticles for potential cellular computed tomography imaging applications

(2013) Hui Liu et al.   ANALYST

Hyperacute direct thrombus imaging using computed tomography and gold nanoparticles

(2013) Dong-Eog Kim et al.   ANNALS OF NEUROLOGY

Graphene-based magnetic plasmonic nanocomposite for dual bioimaging and photothermal therapy

(2013) Xiaoze Shi et al.   BIOMATERIALS

Graphene oxide modified PLA microcapsules containing gold nanoparticles for ultrasonic/CT bimodal imaging guided photothermal tumor therapy

(2013) Yushen Jin et al.   BIOMATERIALS

Targeted CT/MR dual mode imaging of tumors using multifunctional dendrimer-entrapped gold nanoparticles

(2013) Qian Chen et al.   BIOMATERIALS

Evaluation of EGFR-targeted radioimmuno-gold-nanoparticles as a theranostic agent in a tumor animal model

(2013) Hao-Wen Kao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Gold nanoparticle cluster–plasmon-enhanced fluorescent silica core–shell nanoparticles for X-ray computed tomography–fluorescence dual-mode imaging of tumors

(2013) Koichiro Hayashi et al.   CHEMICAL COMMUNICATIONS

Multifunctional dendrimer-based nanoparticles for in vivo MR/CT dual-modal molecular imaging of breast cancer

(2013) Kangan Li et al.   International Journal of Nanomedicine

Tumor Uptake of Hollow Gold Nanospheres After Intravenous and Intra-arterial Injection: PET/CT Study in a Rabbit VX2 Liver Cancer Model

(2013) Mei Tian et al.   MOLECULAR IMAGING AND BIOLOGY

Gold nanoparticle mediated cancer immunotherapy

(2013) Joao Paulo Mattos Almeida et al.   Nanomedicine-Nanotechnology Biology and Medicine

Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics

(2013) Yang Liu et al.   Nanoscale

Biocompatible Glycol Chitosan-Coated Gold Nanoparticles for Tumor-Targeting CT Imaging

(2013) In-Cheol Sun et al.   PHARMACEUTICAL RESEARCH

In vivocharacterization of tumor vasculature using iodine and gold nanoparticles and dual energy micro-CT

(2013) Darin P Clark et al.   PHYSICS IN MEDICINE AND BIOLOGY

In vivo imaging of T cells loaded with gold nanoparticles: a pilot study

(2013) Hui Li et al.   Radiologia Medica

A Simple Route to Prepare Monodisperse Au NP-Decorated, Dye-doped, Superparamagnetic Nanocomposites for Optical, MR, and CT Trimodal Imaging

(2013) Wenjie Dong et al.   Small

Gadolinium-Conjugated Gold Nanoshells for Multimodal Diagnostic Imaging and Photothermal Cancer Therapy

(2013) Andrew J. Coughlin et al.   Small

Folic acid-conjugated silica capped gold nanoclusters for targeted fluorescence/X-ray computed tomography imaging

(2013) Zhijun Zhou et al.   JOURNAL OF NANOBIOTECHNOLOGY

Therapeutic platforms based on gold nanoparticles and their covalent conjugates with drug molecules

(2012) Leonid Vigderman et al.   ADVANCED DRUG DELIVERY REVIEWS

Multifunctional dendrimer-entrapped gold nanoparticles for dual mode CT/MR imaging applications

(2012) Shihui Wen et al.   BIOMATERIALS

Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma

(2012) Han Wang et al.   BIOMATERIALS

The Osmolality of Nonionic, Iodinated Contrast Agents as an Important Factor for Renal Safety

(2012) Diana C. Lenhard et al.   INVESTIGATIVE RADIOLOGY

Effect of the stability and deformability of self-assembled glycol chitosan nanoparticles on tumor-targeting efficiency

(2012) Jin Hee Na et al.   JOURNAL OF CONTROLLED RELEASE

Second generation gold nanobeacons for robust K-edge imaging with multi-energy CT

(2012) Carsten O. Schirra et al.   JOURNAL OF MATERIALS CHEMISTRY

Syntheses and Characterization of Lisinopril-Coated Gold Nanoparticles as Highly Stable Targeted CT Contrast Agents in Cardiovascular Diseases

(2012) William E. Ghann et al.   LANGMUIR

Gold nanoparticle imaging and radiotherapy of brain tumors in mice

(2012) James F Hainfeld et al.   Nanomedicine

Facile formation of dendrimer-stabilized gold nanoparticles modified with diatrizoic acid for enhanced computed tomography imaging applications

(2012) Chen Peng et al.   Nanoscale

Dual Contrast Agent for Computed Tomography and Magnetic Resonance Hard Tissue Imaging

(2012) Manuela Ventura et al.   TISSUE ENGINEERING PART C-METHODS

Near-Infrared Fluorescent Silica-Coated Gold Nanoparticle Clusters for X-Ray Computed Tomography/Optical Dual Modal Imaging of the Lymphatic System

(2012) Koichiro Hayashi et al.   Advanced Healthcare Materials

Evaluation of the effects of gold nanoparticle shape and size on contrast enhancement in radiological imaging

(2011) Price Jackson et al.   AUSTRALASIAN PHYSICAL & ENGINEERING SCIENCES IN MEDICINE

Computed tomography imaging of cancer cells using acetylated dendrimer-entrapped gold nanoparticles

(2011) Han Wang et al.   BIOMATERIALS

PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography

(2011) Chen Peng et al.   BIOMATERIALS

Micro-CT enables microlocalisation and quantification of Her2-targeted gold nanoparticles within tumour regions

(2011) J F Hainfeld et al.   BRITISH JOURNAL OF RADIOLOGY

Amphiphilic polymer-coated hybrid nanoparticles as CT/MRI dual contrast agents

(2011) Dongkyu Kim et al.   NANOTECHNOLOGY

Mesoporous silica-coated gold nanorods with embedded indocyanine green for dual mode X-ray CT and NIR fluorescence imaging

(2011) Teng Luo et al.   OPTICS EXPRESS

Trimodal Gadolinium-Gold Microcapsules Containing Pancreatic Islet Cells Restore Normoglycemia in Diabetic Mice and Can Be Tracked by Using US, CT, and Positive-Contrast MR Imaging

(2011) Dian R. Arifin et al.   RADIOLOGY

Gold Nanoparticle Contrast in a Phantom and Juvenile Swine

(2010) Evan Boote et al.   ACADEMIC RADIOLOGY

A Drug-Loaded Aptamer−Gold Nanoparticle Bioconjugate for Combined CT Imaging and Therapy of Prostate Cancer

(2010) Dongkyu Kim et al.   ACS Nano

A fluorescent, paramagnetic and PEGylated gold/silica nanoparticle for MRI, CT and fluorescence imaging

(2010) Matti M. van Schooneveld et al.   Contrast Media & Molecular Imaging

The Impact of the Viscosity and Osmolality of Iodine Contrast Agents on Renal Elimination

(2010) Gregor Jost et al.   INVESTIGATIVE RADIOLOGY

AuNP-DG: Deoxyglucose-Labeled Gold Nanoparticles as X-ray Computed Tomography Contrast Agents for Cancer Imaging

(2010) Bulent Aydogan et al.   MOLECULAR IMAGING AND BIOLOGY

Anti-CD4-targeted Gold Nanoparticles Induce Specific Contrast Enhancement of Peripheral Lymph Nodes in X-ray Computed Tomography of Live Mice

(2010) Wolfgang Eck et al.   NANO LETTERS

Functionalized gold nanoparticles: a detailed in vivo multimodal microscopic brain distribution study

(2010) Fernanda Sousa et al.   Nanoscale

Preparation of functionalized gold nanoparticles as a targeted X-ray contrast agent for damaged bone tissue

(2010) Zhenyuan Zhang et al.   Nanoscale

X-ray computed tomography contrast agents prepared by seeded growth of gold nanoparticles in PEGylated dendrimer

(2010) Chie Kojima et al.   NANOTECHNOLOGY

An Effective Strategy for the Synthesis of Biocompatible Gold Nanoparticles Using Cinnamon Phytochemicals for Phantom CT Imaging and Photoacoustic Detection of Cancerous Cells

(2010) Nripen Chanda et al.   PHARMACEUTICAL RESEARCH

A novel functional CT contrast agent for molecular imaging of cancer

(2010) Ji Li et al.   PHYSICS IN MEDICINE AND BIOLOGY

Bombesin functionalized gold nanoparticles show in vitro and in vivo cancer receptor specificity

(2010) N. Chanda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atherosclerotic Plaque Composition: Analysis with Multicolor CT and Targeted Gold Nanoparticles

(2010) David P. Cormode et al.   RADIOLOGY

EMI and the First CT Scanner

(2010) Riley E. Alexander et al.   Journal of the American College of Radiology

Computationally Guided Photothermal Tumor Therapy Using Long-Circulating Gold Nanorod Antennas

(2009) G. von Maltzahn et al.   CANCER RESEARCH

Heparin-Coated Gold Nanoparticles for Liver-Specific CT Imaging

(2009) In-Cheol Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Drug loaded microbubble design for ultrasound triggered delivery

(2009) Ine Lentacker et al.   Soft Matter

Gadolinium Chelate Coated Gold Nanoparticles As Contrast Agents for Both X-ray Computed Tomography and Magnetic Resonance Imaging

(2008) Christophe Alric et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted Gold Nanoparticles Enable Molecular CT Imaging of Cancer

(2008) Rachela Popovtzer et al.   NANO LETTERS

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

(2007) Matthias Nahrendorf et al.   CIRCULATION