The Osmolality of Nonionic, Iodinated Contrast Agents as an Important Factor for Renal Safety

Proof of Principle

(2012) Erdmann Seeliger et al.   INVESTIGATIVE RADIOLOGY

TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis

(2011) Rohan Samarakoon et al.   CELL AND TISSUE RESEARCH

Viscosity of iodinated contrast agents during renal excretion

(2011) Gregor Jost et al.   EUROPEAN JOURNAL OF RADIOLOGY

Changes of Renal Water Diffusion Coefficient After Application of Iodinated Contrast Agents

(2011) Gregor Jost et al.   INVESTIGATIVE RADIOLOGY

Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes

(2011) Eugenia Singer et al.   KIDNEY INTERNATIONAL

The Ngal reporter mouse detects the response of the kidney to injury in real time

(2011) Neal Paragas et al.   NATURE MEDICINE

The Impact of the Viscosity and Osmolality of Iodine Contrast Agents on Renal Elimination

(2010) Gregor Jost et al.   INVESTIGATIVE RADIOLOGY

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies

(2010) Vishal S Vaidya et al.   NATURE BIOTECHNOLOGY

Up to 50-fold Increase in Urine Viscosity with Iso-osmolar Contrast Media in the Rat

(2010) Erdmann Seeliger et al.   RADIOLOGY

Retention of Iodine and Expression of Biomarkers for Renal Damage in the Kidney After Application of Iodinated Contrast Media in Rats

(2009) Gregor Jost et al.   INVESTIGATIVE RADIOLOGY